AZD6482 - ≥98%, high purity , PI3-kinase class I inhibitor, CAS No.1173900-33-8, PI3-kinase class I inhibitor

Item Number

A129523

• Synonyms: 2-[[(1R)-1-[7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid | HY-10344 | 2-({(1R)-1-[7-Methyl-2-(morpholin-4-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl}amino)benzoic acid | InChI=1/C7H15N/c1-8-7-5-3-2-4-6-7/h7-
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Potent and selective inhibitor of PI 3-kinaseβ(PI 3-Kβ) (IC50values are 0.69, 13.6, 47.8 and 136 nM for PI 3-Kβ, PI 3-Kδ, PI 3-Kγand PI 3-Kα, respectively). Selectively inhibitsin vivogrowth of the PTEN-deficient tumor xenografts HCC70 and PC3. Also exhib
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: PI3-kinase class I inhibitor
• Note: 卖完停产，不再备货

Product Description

AZD6482 is a PI3Kβ inhibitor with IC50 of 10 nM, 8-, 87- and 109-fold more selective to PI3Kβ than PI3Kδ, PI3Kα and PI3Kγ.
A PI3K inhibitor and antiplatelet agent.