AZD8330 - ≥98%, high purity , Dual specificity mitogen-activated protein kinase kinase 2 inhibitor, CAS No.869357-68-6, Dual specificity mitogen-activated protein kinase kinase 2 inhibitor

Item Number

A127453

• Synonyms: 2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxopyridine-3-carboxamide | HY-12058 | AKOS005257947 | MLS006011055 | NSC799353 | NSC-799353 | SY152450 | AKOS027420927 | EX-A2349 | SCHEMBL388533 | GTPL8474 | NSC772563 | NSC-772563 | J-
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: AZD8330 potently and strongly inhibits MEK 1/2. AZD8330 has no inhibitory activity against over 200 other kinases including at concentrations up to 10 μM. AZD8330 demonstrates sub-nanomolar potency in mechanistic (pERK) and low to sub-nanomolar potency in
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Dual specificity mitogen-activated protein kinase kinase 2 inhibitor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic,\xa0refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM.
An antineoplastic selective MEK inhibitor