The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
AZD9567 , CAS No.A607895, Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor;Agonist of Progesterone receptor
Basic Description Synonyms AZD9567 | 1893415-00-3 | Mizacorat | AZD-9567 | GGK40O1O85 | AZD 9567 [WHO-DD] | UNII-GGK40O1O85 | AZD 9567 | 2,2-difluoro-N-[(1R,2S)-3-methyl-1-[1-(1-methyl-6-oxopyridin-3-yl)indazol-5-yl]oxy-1-phenylbutan-2-yl]propanamide | Propanamide, N-((1S)-1-((R)-((1-(1,6-dihydro-1- Specifications & Purity Moligand™ Grade Moligand™ Action Type AGONIST Mechanism of action Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor;Agonist of Progesterone receptor
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name 2,2-difluoro-N-[(1R,2S)-3-methyl-1-[1-(1-methyl-6-oxopyridin-3-yl)indazol-5-yl]oxy-1-phenylbutan-2-yl]propanamide INCHI InChI=1S/C27H28F2N4O3/c1-17(2)24(31-26(35)27(3,28)29)25(18-8-6-5-7-9-18)36-21-11-12-22-19(14-21)15-30-33(22)20-10-13-23(34)32(4)16-20/h5-17,24-25H,1-4H3,(H,31,35)/t24-,25+/m0/s1 InChi Key ZQFNDBISEYQVRR-LOSJGSFVSA-N Canonical SMILES CC([C@@H]([C@@H](c1ccccc1)Oc1ccc2c(c1)cnn2c1ccc(=O)n(c1)C)NC(=O)C(F)(F)C)C Isomeric SMILES CC(C)[C@@H]([C@@H](C1=CC=CC=C1)OC2=CC3=C(C=C2)N(N=C3)C4=CN(C(=O)C=C4)C)NC(=O)C(C)(F)F PubChem CID 121248172
References 1. Ripa L, Edman K, Dearman M, Edenro G, Hendrickx R, Ullah V, Chang HF, Lepistö M, Chapman D, Geschwindner S et al. . (2018) Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect Profile.. J Med Chem, 61 (5): (1785-1799). [PMID:29424542 ] [10.1021/op500134e ]
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
