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β-Alanine - 98%, high purity , CAS No.107-95-9, Agonist of MRGPRD

32 Citations
Item Number
A137901
Grouped product items
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A137901-25g
25g
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$9.90
A137901-100g
100g
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$11.90
A137901-250g
250g
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$22.90
A137901-500g
500g
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$41.90
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Endogenous glycine agonist

View related series
Glycine Receptor (All subtypes) Agonist MRGPRD Agonist

Basic Description

SynonymsALANINE, BETA | Alanine, beta- | BETA ALANINE [USP-RS] | EC 203-536-5 | HY-N0230 | omega-Aminopropionate | Q310919 | b-Aminopropanoic acid | .BETA.-ALANINE [MI] | 11P2JDE17B | b-Aminopropionate | 3-Aminopropionsaeure | MFCD00008200 | b-Aminopropanoate | b
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological Mechanismsβ-Alanine is an endogenous glycine agonist, more selective than Taurine (sc-202354). β-Alanine can also distinguish between GATs (GABA transporters) (IC50 values are 19, 58, 5690 and 1320 μ M for hGABA T-1, rGABA T-2, hGABA T-3 and hBGT-1 respectively).Fu
Shipped InNormal
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of MRGPRD
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

β-Alanine has been used as a ligand for the orphan MAS-related receptor.[1] It has also been used in culture media used for certain strains of yeast to test for β-alanine auxotrophy.

Associated Targets(Human)

MRGPRD Tchem Mas-related G-protein coupled receptor member D (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC6A1 Tclin GABA transporter 1 (308 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIN1 Tclin Glutamate (NMDA) receptor subunit zeta 1 (122 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A11 Tchem GABA transporter 3 (176 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC36A1 Tchem Proton-coupled amino acid transporter 1 (102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Slc6a13 GABA transporter 2 (37 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc6a11 GABA transporter 4 (930 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
panC Pantothenate synthetase (234 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 3-aminopropanoic acid
INCHI InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)
InChi Key UCMIRNVEIXFBKS-UHFFFAOYSA-N
Canonical SMILES C(CN)C(=O)O
Isomeric SMILES C(CN)C(=O)O
WGK Germany 3
PubChem CID 239
Molecular Weight 89.09
Beilstein 906793
Reaxy-Rn 906793

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

25 results found

Lot NumberCertificate TypeDateItem
K2317214Certificate of AnalysisNov 24, 2023 A137901
K2317213Certificate of AnalysisNov 24, 2023 A137901
K2317212Certificate of AnalysisNov 24, 2023 A137901
K2317211Certificate of AnalysisNov 24, 2023 A137901
K2317210Certificate of AnalysisNov 24, 2023 A137901
G2326092Certificate of AnalysisAug 10, 2023 A137901
G2326097Certificate of AnalysisAug 08, 2023 A137901
G2326096Certificate of AnalysisAug 08, 2023 A137901
G2326093Certificate of AnalysisAug 08, 2023 A137901
G2326091Certificate of AnalysisAug 08, 2023 A137901
C2323087Certificate of AnalysisMar 28, 2023 A137901
C2323076Certificate of AnalysisMar 28, 2023 A137901
C2323085Certificate of AnalysisMar 25, 2023 A137901
C2323089Certificate of AnalysisMar 25, 2023 A137901
C2323079Certificate of AnalysisMar 25, 2023 A137901
C2323075Certificate of AnalysisMar 25, 2023 A137901
B2327042Certificate of AnalysisMar 04, 2023 A137901
B2315562Certificate of AnalysisFeb 24, 2023 A137901
B2314160Certificate of AnalysisFeb 23, 2023 A137901
G2212074Certificate of AnalysisJul 15, 2022 A137901
A2218138Certificate of AnalysisJan 19, 2022 A137901
A2218158Certificate of AnalysisJan 19, 2022 A137901
A2218143Certificate of AnalysisJan 19, 2022 A137901
B2302292Certificate of AnalysisJan 19, 2022 A137901
A2218144Certificate of AnalysisJan 19, 2022 A137901

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Chemical and Physical Properties

Melt Point(°C)205°C

Safety and Hazards(GHS)

WGK Germany 3
Reaxy-Rn 906793
Merck Index 205

Related Documents

 SDS

 Specification Sheet

Citations of This Product

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