Call +1 (833) 552-7181 or Contact us Earn $25 in coupons on your first order with Aladdin!
Toggle Nav
My Cart
Search
Advanced Search
Menu
Sign In
྾
main product photo

β-Nicotinamide Mononucleotide (NMN) - ≥95%, high purity , CAS No.1094-61-7

14 Citations
  • ≥95%
Item Number
N131850
Grouped product items
SKUSizeAvailabilityPrice Qty
N131850-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$9.90
N131850-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$19.90
N131850-500mg
500mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$29.90
N131850-1g
1g
In stock
$39.90
N131850-5g
5g
In stock
$72.90
N131850-25g
25g
In stock
$216.90
N131850-100g
100g
In stock
$519.90
Add to Wish List Compare
Bulk Order  SDS  DATASHEET

Key NAD+ intermediate

View related series
Oxidoreductase

Basic Description

Synonymsnicotinamide ribonucleotide | NMN zwitterion | beta-Nicotinamide mononucleotide | Nicotinamide ribotide | nicotinamide D-ribonucleotide | nicotinamide mononucleotide | beta-nicotinamide D-ribonucleotide | beta-NMN | nicotinamide nucleotide | NMN
Specifications & Purity≥95%
Biochemical and Physiological MechanismsProduct of the NAMPT reaction and\xa0a key intermediate in the biosynthesis of nicotinamide adenine dinucleotide (NAD + ). Ameliorates glucose intolerance by restoring NAD + levels in high-fat diet (HFD)-induced T2D mice. Enhances hepatic insulin sensitiv
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
Note25mg/200mg 中国和美国售完停产 Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

A product of the eNAMPT reaction and a NAD+ intermediate

β-Nicotinamide mononucleotide (NMN) is used to study binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.

β-Nicotinamide mononucleotide is a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.

Associated Targets(Human)

LDHB Tchem L-lactate dehydrogenase B chain (463 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDH1 Tchem Malate dehydrogenase cytoplasmic (119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GAPDH Tchem Glyceraldehyde-3-phosphate dehydrogenase liver (1284 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

GLUD1 Glutamate dehydrogenase (27 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
panE Ketopantoate reductase (28 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488181949
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488181949
IUPAC Name [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate
INCHI InChI=1S/C11H15N2O8P/c12-10(16)6-2-1-3-13(4-6)11-9(15)8(14)7(21-11)5-20-22(17,18)19/h1-4,7-9,11,14-15H,5H2,(H3-,12,16,17,18,19)/t7-,8-,9-,11-/m1/s1
InChi Key DAYLJWODMCOQEW-TURQNECASA-N
Canonical SMILES C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)[O-])O)O)C(=O)N
Isomeric SMILES C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)[O-])O)O)C(=O)N
WGK Germany 3
PubChem CID 14180
Molecular Weight 334.22
Beilstein 3570187

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

35 results found

Lot NumberCertificate TypeDateItem
K2421511Certificate of AnalysisNov 08, 2024 N131850
K2421508Certificate of AnalysisNov 08, 2024 N131850
K2421504Certificate of AnalysisNov 08, 2024 N131850
K2421499Certificate of AnalysisNov 08, 2024 N131850
H2231896Certificate of AnalysisJun 19, 2024 N131850
H2231705Certificate of AnalysisJun 19, 2024 N131850
H2231626Certificate of AnalysisJun 19, 2024 N131850
J2425770Certificate of AnalysisApr 23, 2024 N131850
J2425769Certificate of AnalysisApr 23, 2024 N131850
J2425643Certificate of AnalysisApr 23, 2024 N131850
L2107071Certificate of AnalysisSep 19, 2023 N131850
L2106810Certificate of AnalysisSep 19, 2023 N131850
L2106693Certificate of AnalysisSep 19, 2023 N131850
G2321649Certificate of AnalysisJun 13, 2023 N131850
I2405021Certificate of AnalysisJun 13, 2023 N131850
G2321642Certificate of AnalysisJun 13, 2023 N131850
G2321634Certificate of AnalysisJun 13, 2023 N131850
G2321628Certificate of AnalysisJun 13, 2023 N131850
G2321302Certificate of AnalysisJun 13, 2023 N131850
G2321285Certificate of AnalysisJun 13, 2023 N131850
G2109284Certificate of AnalysisApr 18, 2023 N131850
G2109283Certificate of AnalysisApr 18, 2023 N131850
G2109282Certificate of AnalysisApr 18, 2023 N131850
B2328602Certificate of AnalysisFeb 16, 2023 N131850
B2328606Certificate of AnalysisFeb 16, 2023 N131850
B2328607Certificate of AnalysisFeb 16, 2023 N131850
B2328608Certificate of AnalysisFeb 16, 2023 N131850
B2328936Certificate of AnalysisFeb 16, 2023 N131850
B2328601Certificate of AnalysisFeb 16, 2023 N131850
H2231700Certificate of AnalysisJun 18, 2022 N131850
H2231625Certificate of AnalysisJun 18, 2022 N131850
H2231624Certificate of AnalysisJun 18, 2022 N131850
C2226312Certificate of AnalysisFeb 17, 2022 N131850
C2226284Certificate of AnalysisFeb 17, 2022 N131850
C2226321Certificate of AnalysisFeb 17, 2022 N131850

Show more⌵

Chemical and Physical Properties

SolubilitySoluble in PBS (10 mg/ml).
Sensitivityheat sensitive
Specific Rotation[α]-24° (C=2,H2O)
Melt Point(°C)166 °C

Safety and Hazards(GHS)

WGK Germany 3
Merck Index 6663

Related Documents

 SDS

 Specification Sheet

Alternative Products

  1. β-Nicotinamide Mononucleotide (NMN) - 10mM in Water, used for , CAS No. , by Aladdin Scientific
    β-Nicotinamide Mononucleotide (NMN)
    • 10mM in Water

    Starting at $182.90

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Jiyan Xu, Xinlu Chen, Shuai Liu, Ziqi Wei, Minhui Xu, Linhao Jiang, Xue Han, Liangyu Peng, Xiaoping Gu, Tianjiao Xia.  (2023)  Nicotinamide mononucleotide pretreatment improves long-term isoflurane anesthesia-induced cognitive impairment in mice.  BEHAVIOURAL BRAIN RESEARCH,    (14): (114738).  [PMID:37931707] [10.1016/j.bbr.2023.114738]
2. Qi Shen, Shi-Jia Zhang, Bin-Hui Xu, Zhi-Yu Chen, Feng Peng, Neng Xiong, Ya-Ping Xue, Yu-Guo Zheng.  (2023)  Semirational engineering of Cytophaga hutchinsonii polyphosphate kinase for developing a cost-effective, robust, and efficient adenosine 5′-triphosphate regeneration system.  APPLIED AND ENVIRONMENTAL MICROBIOLOGY,      [PMID:37902313] [10.1128/aem.01106-23]
3. Ruixue Duan, Yueping Li, Ruru Zhang, Xuelan Hu, Yi wang, Jianfeng Zeng, Mingyuan Gao.  (2023)  Reversing Acute Kidney Injury Through Coordinated Interplay of Anti-inflammation and Iron Supplementation.  ADVANCED MATERIALS,    (2301283).  [PMID:37029662] [10.1002/adma.202301283]
4. Zhuhui Chen, Yue Xiong, Ranran Ma, Pei Chen, Le Duan, Shuying Yang, Ineza Urujeni Gisèle, Linjun You, Deli Xiao.  (2023)  A novel magnetic fluid for ultra-fast and highly efficient extraction of N1-methylnicotinamide in urine samples.  NEW JOURNAL OF CHEMISTRY,  47  (16): (7862-7872).  [PMID:] [10.1039/D3NJ00488K]
5. Wu Yue, Yang Jingjuan, Xu Chengmei, Li Qiuqi, Ma Yage, Zhao Shenglan, Zhuang Jiachen, Shen Fei, Wang Qianqian, Feng Fengqin, Zhang Xi.  (2022)  Sea cucumber (Acaudina leucoprocta) peptides extended the lifespan and enhanced antioxidant capacity via DAF-16/DAF-2/SOD-3/OLD-1/PEPT-1 in Caenorhabditis elegans.  Frontiers in Nutrition,  9    [PMID:36483922] [10.3389/fnut.2022.1065145]
6. Zhongshi Huang, Ning Li, Shiqin Yu, Weiping Zhang, Tianmeng Zhang, Jingwen Zhou.  (2022)  Systematic Engineering of Escherichia coli for Efficient Production of Nicotinamide Mononucleotide From Nicotinamide.  ACS Synthetic Biology,  11  (9): (2979–2988).  [PMID:35977419] [10.1021/acssynbio.2c00100]
7. Jinhui Hu, Ting Wang, Lin Zhou, Shaohua Wei.  (2020)  A ROS responsive nanomedicine with enhanced photodynamic therapy via dual mechanisms: GSH depletion and biosynthesis inhibition.  JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY,  209  (111955).  [PMID:32653858] [10.1016/j.jphotobiol.2020.111955]
8. Zhang Weihong, Wang Dan, Wang Jie-Xin, Pu Yuan, Chen Jian-Feng.  (2020)  High-gravity-assisted emulsification for continuous preparation of waterborne polyurethane nanodispersion with high solids content.  Frontiers of Chemical Science and Engineering,  14  (6): (1087-1099).  [PMID:] [10.1007/s11705-019-1895-z]
9. Guohan Sun, Shiqiao Wang, Jianfeng Zhou, Jianbin Pan, Yanli Tong, Qinghua Mei, Haiyun Zhai.  (2020)  Constructing a simple and sensitive electrochemical sensor for the determination of NMN based on p-m-ABSA film modified glassy carbon electrode.  MICROCHEMICAL JOURNAL,  152  (104438).  [PMID:] [10.1016/j.microc.2019.104438]
10. Dengcheng Huang, Yu Zhou, Yuan Xiang, Meijie Shu, Hongxiang Chen, Bing Yang, Xinghua Liao.  (2018)  Polyurethane/doxorubicin nanoparticles based on electrostatic interactions as pH-sensitive drug delivery carriers.  POLYMER INTERNATIONAL,  67  (9): (1186-1193).  [PMID:] [10.1002/pi.5618]
11. Ma Le, Song Lina, Li Fang, Wang Heng, Liu Baohua.  (2017)  Preparation and properties of poly (propylene carbonate)-based waterborne polyurethane-acrylate composite emulsion.  COLLOID AND POLYMER SCIENCE,  295  (12): (2299-2307).  [PMID:] [10.1007/s00396-017-4198-2]
12. Caideng Yuan, Mengyao Wang, Haitao Li, Zhongwei Wang.  (2017)  Preparation and properties of UV-curable waterborne polyurethane–acrylate emulsion.  JOURNAL OF APPLIED POLYMER SCIENCE,  134  (34): (45208).  [PMID:] [10.1002/app.45208]
13. Di Liu, Guo-Min Wu, Zhen-Wu Kong.  (2016)  Preparation and characterization of a polydimethylsiloxane-modified, epoxy-resin-based polyol dispersion and its crosslinked films.  JOURNAL OF APPLIED POLYMER SCIENCE,  134  (1):   [PMID:] [10.1002/app.44342]
14. Sude Ma, Guolin Song, Ningbo Feng.  (2012)  Preparation and characterization of self-emulsified waterborne nitrocellulose.  CARBOHYDRATE POLYMERS,  89  (36).  [PMID:24750600] [10.1016/j.carbpol.2012.02.029]

References

1. Jiyan Xu, Xinlu Chen, Shuai Liu, Ziqi Wei, Minhui Xu, Linhao Jiang, Xue Han, Liangyu Peng, Xiaoping Gu, Tianjiao Xia.  (2023)  Nicotinamide mononucleotide pretreatment improves long-term isoflurane anesthesia-induced cognitive impairment in mice.  BEHAVIOURAL BRAIN RESEARCH,    (14): (114738).  [PMID:37931707] [10.1016/j.bbr.2023.114738]
2. Qi Shen, Shi-Jia Zhang, Bin-Hui Xu, Zhi-Yu Chen, Feng Peng, Neng Xiong, Ya-Ping Xue, Yu-Guo Zheng.  (2023)  Semirational engineering of Cytophaga hutchinsonii polyphosphate kinase for developing a cost-effective, robust, and efficient adenosine 5′-triphosphate regeneration system.  APPLIED AND ENVIRONMENTAL MICROBIOLOGY,      [PMID:37902313] [10.1128/aem.01106-23]
3. Ruixue Duan, Yueping Li, Ruru Zhang, Xuelan Hu, Yi wang, Jianfeng Zeng, Mingyuan Gao.  (2023)  Reversing Acute Kidney Injury Through Coordinated Interplay of Anti-inflammation and Iron Supplementation.  ADVANCED MATERIALS,    (2301283).  [PMID:37029662] [10.1002/adma.202301283]
4. Zhuhui Chen, Yue Xiong, Ranran Ma, Pei Chen, Le Duan, Shuying Yang, Ineza Urujeni Gisèle, Linjun You, Deli Xiao.  (2023)  A novel magnetic fluid for ultra-fast and highly efficient extraction of N1-methylnicotinamide in urine samples.  NEW JOURNAL OF CHEMISTRY,  47  (16): (7862-7872).  [PMID:] [10.1039/D3NJ00488K]
5. Wu Yue, Yang Jingjuan, Xu Chengmei, Li Qiuqi, Ma Yage, Zhao Shenglan, Zhuang Jiachen, Shen Fei, Wang Qianqian, Feng Fengqin, Zhang Xi.  (2022)  Sea cucumber (Acaudina leucoprocta) peptides extended the lifespan and enhanced antioxidant capacity via DAF-16/DAF-2/SOD-3/OLD-1/PEPT-1 in Caenorhabditis elegans.  Frontiers in Nutrition,  9    [PMID:36483922] [10.3389/fnut.2022.1065145]
6. Zhongshi Huang, Ning Li, Shiqin Yu, Weiping Zhang, Tianmeng Zhang, Jingwen Zhou.  (2022)  Systematic Engineering of Escherichia coli for Efficient Production of Nicotinamide Mononucleotide From Nicotinamide.  ACS Synthetic Biology,  11  (9): (2979–2988).  [PMID:35977419] [10.1021/acssynbio.2c00100]
7. Jinhui Hu, Ting Wang, Lin Zhou, Shaohua Wei.  (2020)  A ROS responsive nanomedicine with enhanced photodynamic therapy via dual mechanisms: GSH depletion and biosynthesis inhibition.  JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY,  209  (111955).  [PMID:32653858] [10.1016/j.jphotobiol.2020.111955]
8. Zhang Weihong, Wang Dan, Wang Jie-Xin, Pu Yuan, Chen Jian-Feng.  (2020)  High-gravity-assisted emulsification for continuous preparation of waterborne polyurethane nanodispersion with high solids content.  Frontiers of Chemical Science and Engineering,  14  (6): (1087-1099).  [PMID:] [10.1007/s11705-019-1895-z]
9. Guohan Sun, Shiqiao Wang, Jianfeng Zhou, Jianbin Pan, Yanli Tong, Qinghua Mei, Haiyun Zhai.  (2020)  Constructing a simple and sensitive electrochemical sensor for the determination of NMN based on p-m-ABSA film modified glassy carbon electrode.  MICROCHEMICAL JOURNAL,  152  (104438).  [PMID:] [10.1016/j.microc.2019.104438]
10. Dengcheng Huang, Yu Zhou, Yuan Xiang, Meijie Shu, Hongxiang Chen, Bing Yang, Xinghua Liao.  (2018)  Polyurethane/doxorubicin nanoparticles based on electrostatic interactions as pH-sensitive drug delivery carriers.  POLYMER INTERNATIONAL,  67  (9): (1186-1193).  [PMID:] [10.1002/pi.5618]
11. Ma Le, Song Lina, Li Fang, Wang Heng, Liu Baohua.  (2017)  Preparation and properties of poly (propylene carbonate)-based waterborne polyurethane-acrylate composite emulsion.  COLLOID AND POLYMER SCIENCE,  295  (12): (2299-2307).  [PMID:] [10.1007/s00396-017-4198-2]
12. Caideng Yuan, Mengyao Wang, Haitao Li, Zhongwei Wang.  (2017)  Preparation and properties of UV-curable waterborne polyurethane–acrylate emulsion.  JOURNAL OF APPLIED POLYMER SCIENCE,  134  (34): (45208).  [PMID:] [10.1002/app.45208]
13. Di Liu, Guo-Min Wu, Zhen-Wu Kong.  (2016)  Preparation and characterization of a polydimethylsiloxane-modified, epoxy-resin-based polyol dispersion and its crosslinked films.  JOURNAL OF APPLIED POLYMER SCIENCE,  134  (1):   [PMID:] [10.1002/app.44342]
14. Sude Ma, Guolin Song, Ningbo Feng.  (2012)  Preparation and characterization of self-emulsified waterborne nitrocellulose.  CARBOHYDRATE POLYMERS,  89  (36).  [PMID:24750600] [10.1016/j.carbpol.2012.02.029]

Solution Calculators

Privacy Policy Website Terms of Use Return policy Terms and Conditions of Sale Cookie Policy Sales Policy
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Copyright © 2023-present Aladdin Scientific Corp . All rights reserved.