Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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S111182-5g | 5g | In stock | $35.90 | |
S111182-25g | 25g | In stock | $68.90 | |
S111182-100g | 100g | In stock | $188.90 | |
S111182-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $755.90 |
Plant sterol. Various pharmacological effects. Antitumor agent
Synonyms | SITO | BSPBio_001049 | Rhamnol | 24-alpha-Ethylcholesterol | 24alpha-Ethylcholesterol | SITOSTEROL (MART.) | Sitosterol, .beta. | (3S,8S,9S,10R,13R,14S,17R)-17-[(1R,4R)-4-ethyl-1,5-dimethyl-hexyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1 |
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Specifications & Purity | ≥75% |
Biochemical and Physiological Mechanisms | β-Sitosterol is a plant sterol that has hypocholesterolemic activity. Only 5% of β-Sitosterol is absorbed by humans. It is hypothesized that the cholesterol-lowering activity is by competing cholesterol for uptake by the cells or by interfering with the e |
Storage Temp | Store at -20°C,Argon charged |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | β-Sitosterol was used to supplement diet of mice to study its effect on body mass accumulation |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol |
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INCHI | InChI=1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-21,23-27,30H,7-9,11-18H2,1-6H3/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1 |
InChi Key | KZJWDPNRJALLNS-VJSFXXLFSA-N |
Canonical SMILES | CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C |
Isomeric SMILES | CC[C@H](CC[C@@H](C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)C(C)C |
WGK Germany | 3 |
RTECS | WJ2600000 |
PubChem CID | 222284 |
Molecular Weight | 414.71 |
Beilstein | 1916165 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
L2410097 | Certificate of Analysis | Sep 28, 2024 | S111182 |
J2421895 | Certificate of Analysis | Sep 28, 2024 | S111182 |
J2421891 | Certificate of Analysis | Sep 28, 2024 | S111182 |
J2421888 | Certificate of Analysis | Sep 28, 2024 | S111182 |
J2421887 | Certificate of Analysis | Sep 28, 2024 | S111182 |
J2421871 | Certificate of Analysis | Sep 28, 2024 | S111182 |
I2319529 | Certificate of Analysis | Sep 04, 2023 | S111182 |
I2319528 | Certificate of Analysis | Sep 04, 2023 | S111182 |
I2319503 | Certificate of Analysis | Sep 04, 2023 | S111182 |
I2319502 | Certificate of Analysis | Sep 04, 2023 | S111182 |
I2319501 | Certificate of Analysis | Sep 04, 2023 | S111182 |
I2319500 | Certificate of Analysis | Sep 04, 2023 | S111182 |
I2311213 | Certificate of Analysis | Aug 14, 2023 | S111182 |
I2311755 | Certificate of Analysis | Aug 14, 2023 | S111182 |
A2306965 | Certificate of Analysis | Dec 02, 2022 | S111182 |
E2308136 | Certificate of Analysis | Dec 02, 2022 | S111182 |
D2328011 | Certificate of Analysis | Dec 02, 2022 | S111182 |
D2312266 | Certificate of Analysis | Dec 02, 2022 | S111182 |
A2307023 | Certificate of Analysis | Dec 02, 2022 | S111182 |
A2307022 | Certificate of Analysis | Dec 02, 2022 | S111182 |
A2307016 | Certificate of Analysis | Dec 02, 2022 | S111182 |
A2307015 | Certificate of Analysis | Dec 02, 2022 | S111182 |
K2228689 | Certificate of Analysis | Nov 04, 2022 | S111182 |
G2222404 | Certificate of Analysis | Jul 26, 2022 | S111182 |
G2219241 | Certificate of Analysis | Jul 21, 2022 | S111182 |
F2121305 | Certificate of Analysis | Jun 26, 2021 | S111182 |
F2121281 | Certificate of Analysis | Jun 26, 2021 | S111182 |
F2121278 | Certificate of Analysis | Jun 26, 2021 | S111182 |
F2121277 | Certificate of Analysis | Jun 26, 2021 | S111182 |
Melt Point(°C) | 139-142℃ |
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WGK Germany | 3 |
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RTECS | WJ2600000 |
Merck Index | 8556 |
Starting at $136.90
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31. Kedong Tai, Michael Rappolt, Xiaoye He, Yang Wei, Shaoxin Zhu, Jingbo Zhang, Like Mao, Yanxiang Gao, Fang Yuan. (2019) Effect of β-sitosterol on the curcumin-loaded liposomes: Vesicle characteristics, physicochemical stability, in vitro release and bioavailability. FOOD CHEMISTRY, 293 (92). [PMID:31151654] [10.1016/j.foodchem.2019.04.077] |
32. Jin-Xiu Liang, Qun-Qun Zhang, Yan-Fei Huang, Han-Qing Pang, Xin-Guang Liu, Wen Gao, Ping Li, Hua Yang. (2019) Comprehensive chemical profiling of monascus-fermented rice product and screening of lipid-lowering compounds other than monacolins. JOURNAL OF ETHNOPHARMACOLOGY, 238 (111879). [PMID:30991138] [10.1016/j.jep.2019.111879] |
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36. Cui Beijiao, Liu Haiyan, Yu Huan, Pang Xiaoya, Yan Hongyuan, Bai Ligai. (2019) Monolithic Material Prepared with Nanodiamond as Monomer for the Enrichment of β-Sitosterol in Edible Oil. Food Analytical Methods, 12 (3): (697-704). [PMID:] [10.1007/s12161-018-1405-9] |
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41. Kedong Tai, Fuguo Liu, Xiaoye He, Peihua Ma, Like Mao, Yanxiang Gao, Fang Yuan. (2018) The effect of sterol derivatives on properties of soybean and egg yolk lecithin liposomes: Stability, structure and membrane characteristics. FOOD RESEARCH INTERNATIONAL, 109 (24). [PMID:29803447] [10.1016/j.foodres.2018.04.014] |
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31. Kedong Tai, Michael Rappolt, Xiaoye He, Yang Wei, Shaoxin Zhu, Jingbo Zhang, Like Mao, Yanxiang Gao, Fang Yuan. (2019) Effect of β-sitosterol on the curcumin-loaded liposomes: Vesicle characteristics, physicochemical stability, in vitro release and bioavailability. FOOD CHEMISTRY, 293 (92). [PMID:31151654] [10.1016/j.foodchem.2019.04.077] |
32. Jin-Xiu Liang, Qun-Qun Zhang, Yan-Fei Huang, Han-Qing Pang, Xin-Guang Liu, Wen Gao, Ping Li, Hua Yang. (2019) Comprehensive chemical profiling of monascus-fermented rice product and screening of lipid-lowering compounds other than monacolins. JOURNAL OF ETHNOPHARMACOLOGY, 238 (111879). [PMID:30991138] [10.1016/j.jep.2019.111879] |
33. Liangxiao Zhang, Sujun Wang, Ruinan Yang, Jin Mao, Jun Jiang, Xiupin Wang, Wen Zhang, Qi Zhang, Peiwu Li. (2019) Simultaneous determination of tocopherols, carotenoids and phytosterols in edible vegetable oil by ultrasound-assisted saponification, LLE and LC-MS/MS. FOOD CHEMISTRY, 289 (313). [PMID:30955618] [10.1016/j.foodchem.2019.03.067] |
34. Bin Guo, Huimin Wang, Danan Lan, Xiaomin Pang, Yiming Li, Haiyan Liu, Hongyuan Yan, Ligai Bai. (2019) Effect of different initiators on temperature-sensitive monolithic columns and application in online enrichment of β-sitosterol. JOURNAL OF APPLIED POLYMER SCIENCE, 136 (25): (47683). [PMID:] [10.1002/app.47683] |
35. Huimin Wang, Haiyan Liu, Bin Guo, Dandan Lan, Xiaomin Pang, Hongyuan Yan, Dandan Han, Huaizhong Guo, Ligai Bai. (2019) A novel poly (NMA-co-DEA-co-EDMA) monolithic column as a sorbent for online solid-phase extraction and its application in the determination of β-sitosterol in plant oil samples. FOOD CHEMISTRY, 278 (594). [PMID:30583417] [10.1016/j.foodchem.2018.11.104] |
36. Cui Beijiao, Liu Haiyan, Yu Huan, Pang Xiaoya, Yan Hongyuan, Bai Ligai. (2019) Monolithic Material Prepared with Nanodiamond as Monomer for the Enrichment of β-Sitosterol in Edible Oil. Food Analytical Methods, 12 (3): (697-704). [PMID:] [10.1007/s12161-018-1405-9] |
37. Wang Huimin, Guo Bin, Pang Xiaoya, Yu Huan, Liu Haiyan, Yan Hongyuan, Han Dandan, Guo Huaizhong, Bai Ligai. (2019) Simultaneous Determination and Enrichment of β-Sitosterol From Edible Oil Samples Using Poly(NMA-ST-co-TAIC-co-EDMA) Monolith as Sorbent with On-line SPE-HPLC. CHROMATOGRAPHIA, 82 (8): (1285-1293). [PMID:] [10.1007/s10337-018-3646-6] |
38. Di Xu, Mengyun Wu, Xue Li, Mingyu Xia, Dongchun Liu, Yinghui Dai, Qing Yu, Bin Wu, Dong Wang. (2018) Cloning, prokaryotic expression and function of the Bufo bufo gargarizans 3β-hydroxysteroid dehydrogenase (3βHSD) gene. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 120 (673). [PMID:30170058] [10.1016/j.ijbiomac.2018.08.165] |
39. Shanshan Wang, Shanshan Wu, Songbai Liu. (2019) Integration of (+)-catechin and β-sitosterol to achieve excellent radical-scavenging activity in emulsions. FOOD CHEMISTRY, 272 (596). [PMID:30309587] [10.1016/j.foodchem.2018.08.098] |
40. Yang Shu, Zhu Minpeng, Wang Na, Cui Xiaotong, Xu Qing, Saleh Ahmed S. M., Duan Yumin, Xiao Zhigang. (2018) Influence of Oil Type on Characteristics of β-Sitosterol and Stearic Acid Based Oleogel. Food Biophysics, 13 (4): (362-373). [PMID:] [10.1007/s11483-018-9542-7] |
41. Kedong Tai, Fuguo Liu, Xiaoye He, Peihua Ma, Like Mao, Yanxiang Gao, Fang Yuan. (2018) The effect of sterol derivatives on properties of soybean and egg yolk lecithin liposomes: Stability, structure and membrane characteristics. FOOD RESEARCH INTERNATIONAL, 109 (24). [PMID:29803447] [10.1016/j.foodres.2018.04.014] |
42. Yang Shu, Li Guode, Saleh Ahmed S. M., Yang Hongli, Wang Na, Wang Peng, Yue Xiqing, Xiao Zhigang. (2017) Functional Characteristics of Oleogel Prepared from Sunflower Oil with β-Sitosterol and Stearic Acid. JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 94 (9): (1153-1164). [PMID:] [10.1007/s11746-017-3026-7] |
43. Xixi Wang, Xueying Li, Xiaoya Jiang, Peipei Dong, Haiyan Liu, Ligai Bai, Hongyuan Yan. (2017) Preparation of a poly(styrene-co-DPHA-co-EDMA) monolith and its application for the separation of small molecules and biomacromolecules by HPLC. TALANTA, 165 (339). [PMID:28153264] [10.1016/j.talanta.2016.12.071] |
44. Li-Juan Han, Lin Li, Lei Zhao, Bing Li, Guo-Qin Liu, Xin-Qi Liu, Xue-De Wang. (2013) Rheological properties of organogels developed by sitosterol and lecithin. FOOD RESEARCH INTERNATIONAL, 53 (42). [PMID:] [10.1016/j.foodres.2013.03.039] |