bay 11-7082|19542-67-7|(E)-3-Tosylacrylonitrile|(E)-3-(p-Toluenesulfonyl)acrylonitrile|Bay 11-7821|BAY-11-7082|BAY11-7082|(E)-3-(4-Methylphenyl)sulfonylprop-2-enenitrile|BAY-11-7821|3-(4-methylphenylsulfonyl)-2-propenenitrile|C10H9NO2S|BAY-117821|3-(p-Tol
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
BAY 11-7082, a potential anti-inflammatory agent, is an irreversible inhibitor of IKK α and phosphorylation of cytokine-inducible IκBα (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-α, NFKBIA; IC50=10 μM). In intact HUVECs,
Storage Temp
Store at 2-8°C,Argon charged
Shipped In
Wet ice
Grade
Moligand™
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
BAY 11-7082 is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM. Also inhibiting components of the ubiquitin system. An anti-inflammatory agent and NFκB inhibitor
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