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BAY-X 1005 - ≥98%(HPLC), high purity , 5-lipoxygenase activating protein inhibitor, CAS No.128253-31-6, 5-lipoxygenase activating protein inhibitor
5-lipoxygenase activating protein (FLAP) inhibitor
Basic Description Synonyms (2R)-2-cyclopentyl-2-[4-(quinolin-2-ylmethoxy)phenyl]acetic acid | (R)-Cyclopentyl-[4-(quinolin-2-ylmethoxy)-phenyl]-acetic acid | BAY-X 1005 | ZEYYDOLCHFETHQ-JOCHJYFZSA-N | (+)-(2R)-CYCLOPENTYL(QUINOLIN-2-YLMETHOXY)ACETIC ACID | Veliflapon (USAN/INN) | 2 Specifications & Purity Moligand™, ≥98%(HPLC) Biochemical and Physiological Mechanisms 5-lipoxygenase activating protein (FLAP) inhibitor. Inhibits the synthesis of leukotrienes B4and C4in animal models; inhibits synthesis of leukotriene B4in A23187-stimulated leukocytes (IC50values are 0.026, 0.039 and 0.22μM for rat, mice and human leukoc Storage Temp Room temperature Shipped In Normal Grade Moligand™ Action Type INHIBITOR Mechanism of action 5-lipoxygenase activating protein inhibitor
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name (2R)-2-cyclopentyl-2-[4-(quinolin-2-ylmethoxy)phenyl]acetic acid INCHI InChI=1S/C23H23NO3/c25-23(26)22(17-6-1-2-7-17)18-10-13-20(14-11-18)27-15-19-12-9-16-5-3-4-8-21(16)24-19/h3-5,8-14,17,22H,1-2,6-7,15H2,(H,25,26)/t22-/m1/s1 InChi Key ZEYYDOLCHFETHQ-JOCHJYFZSA-N Canonical SMILES C1CCC(C1)C(C2=CC=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)C(=O)O Isomeric SMILES C1CCC(C1)[C@H](C2=CC=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)C(=O)O PubChem CID 123723 Molecular Weight 361.43
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 36.14, Max Conc. mM: 100
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H302: Harmful if swallowed
Precautionary Statements P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P301+P317: IF SWALLOWED: Get medical help.
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