(±)-BAYK8644 - ≥98%, high purity , CAS No.71145-03-4, Activator of Ca v1.1;Activator of Ca v1.2;Activator of Ca v1.3;Activator of Ca v1.4

Item Number

B275937

• Synonyms: HMS1791O20 | NCGC00015124-08 | NCGC00260871-01 | Tox21_500186 | BCP15942 | NCGC00015124-07 | SR-01000075305 | GTPL2511 | HMS3371N20 | HMS3886L19 | R(+)-BAY K 8644 | 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Potent L-type Ca 2+ channel activator (EC 50 = 17.3 nM). Centrally active following systemic administration.
• Storage Temp: Store at -20°C,Desiccated
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: ACTIVATOR
• Mechanism of action: Activator of Ca v1.1;Activator of Ca v1.2;Activator of Ca v1.3;Activator of Ca v1.4
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Product Describtion:

Bay K 8644, a dihydropyridine compound, is a specific L-type Ca2+ channel agonist. Bay K 8644 increases Ca2+ influx through sarcolemmal Ca2+ channels by increasing the open time of the channel.