BC-11-38 - 97%, high purity , CAS No.686770-80-9, Inhibitor of phosphodiesterase 11A

Item Number
B275042
Grouped product items
SKUSizeAvailabilityPrice Qty
B275042-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$76.90
B275042-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$89.90
B275042-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$196.90
B275042-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$289.90
B275042-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$486.90
B275042-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$946.90

Potent, selective PDE-11 inhibitor

Basic Description

Specifications & PurityMoligand™, ≥97%
Biochemical and Physiological MechanismsPotent, selective inhibitor phosphodiesterase PDE-11 inhibitor (IC 50 = 0.28 μM). IC 50 s for PDE1-10 are greater than 100 μM. Significantly elevates cAMP levels and cortisol production in H295R human adenocarcinoma cells.
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of phosphodiesterase 11A
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at Room Temperature. The product can be stored for up to 12 months.

Associated Targets(Human)

PDE11A Tchem Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE3A Tclin Phosphodiesterase 3A (3309 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE4A Tclin Phosphodiesterase 4A (1943 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE1B Tclin Phosphodiesterase 1B (178 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE7A Tclin Phosphodiesterase 7A (1104 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE11A Tchem Phosphodiesterase 11A (449 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE9A Tchem Phosphodiesterase 9A (1131 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE10A Tclin Phosphodiesterase 10A (5542 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

PDE2A Phosphodiesterase 2A (77 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE6C Phosphodiesterase 6C (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pde8a Phosphodiesterase 8A (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 3-phenyl-2-propylsulfanyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one
INCHI InChI=1S/C15H16N2OS2/c1-2-9-20-15-16-12-8-10-19-13(12)14(18)17(15)11-6-4-3-5-7-11/h3-7H,2,8-10H2,1H3
InChi Key YHNDCCKFNWDQGW-UHFFFAOYSA-N
Canonical SMILES CCCSC1=NC2=C(C(=O)N1C3=CC=CC=C3)SCC2
Isomeric SMILES CCCSC1=NC2=C(C(=O)N1C3=CC=CC=C3)SCC2
PubChem CID 2052828
Molecular Weight 304.43

Certificates

Certificate of Analysis(COA)

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12 results found

Lot NumberCertificate TypeDateItem
D2419092Certificate of AnalysisJan 29, 2024 B275042
D2419094Certificate of AnalysisJan 29, 2024 B275042
D2419095Certificate of AnalysisJan 29, 2024 B275042
D2419096Certificate of AnalysisJan 29, 2024 B275042
D2419097Certificate of AnalysisJan 29, 2024 B275042
D2419098Certificate of AnalysisJan 29, 2024 B275042
D2419100Certificate of AnalysisJan 29, 2024 B275042
D2419101Certificate of AnalysisJan 29, 2024 B275042
D2419102Certificate of AnalysisJan 29, 2024 B275042
D2419103Certificate of AnalysisJan 29, 2024 B275042
D2419104Certificate of AnalysisJan 29, 2024 B275042
D2419105Certificate of AnalysisJan 29, 2024 B275042

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