Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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B275042-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $76.90 | |
B275042-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $89.90 | |
B275042-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $196.90 | |
B275042-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $289.90 | |
B275042-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $486.90 | |
B275042-250mg | 250mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $946.90 |
Potent, selective PDE-11 inhibitor
Specifications & Purity | Moligand™, ≥97% |
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Biochemical and Physiological Mechanisms | Potent, selective inhibitor phosphodiesterase PDE-11 inhibitor (IC 50 = 0.28 μM). IC 50 s for PDE1-10 are greater than 100 μM. Significantly elevates cAMP levels and cortisol production in H295R human adenocarcinoma cells. |
Storage Temp | Store at 2-8°C,Argon charged |
Shipped In | Wet ice |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of phosphodiesterase 11A |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Store at Room Temperature. The product can be stored for up to 12 months. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 3-phenyl-2-propylsulfanyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one |
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INCHI | InChI=1S/C15H16N2OS2/c1-2-9-20-15-16-12-8-10-19-13(12)14(18)17(15)11-6-4-3-5-7-11/h3-7H,2,8-10H2,1H3 |
InChi Key | YHNDCCKFNWDQGW-UHFFFAOYSA-N |
Canonical SMILES | CCCSC1=NC2=C(C(=O)N1C3=CC=CC=C3)SCC2 |
Isomeric SMILES | CCCSC1=NC2=C(C(=O)N1C3=CC=CC=C3)SCC2 |
PubChem CID | 2052828 |
Molecular Weight | 304.43 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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D2419092 | Certificate of Analysis | Jan 29, 2024 | B275042 |
D2419094 | Certificate of Analysis | Jan 29, 2024 | B275042 |
D2419095 | Certificate of Analysis | Jan 29, 2024 | B275042 |
D2419096 | Certificate of Analysis | Jan 29, 2024 | B275042 |
D2419097 | Certificate of Analysis | Jan 29, 2024 | B275042 |
D2419098 | Certificate of Analysis | Jan 29, 2024 | B275042 |
D2419100 | Certificate of Analysis | Jan 29, 2024 | B275042 |
D2419101 | Certificate of Analysis | Jan 29, 2024 | B275042 |
D2419102 | Certificate of Analysis | Jan 29, 2024 | B275042 |
D2419103 | Certificate of Analysis | Jan 29, 2024 | B275042 |
D2419104 | Certificate of Analysis | Jan 29, 2024 | B275042 |
D2419105 | Certificate of Analysis | Jan 29, 2024 | B275042 |