JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

྾

Home
Bioactive Small Molecules
BCI - 99%, high purity , CAS No.1245792-51-1

Skip to the end of the images gallery

Skip to the beginning of the images gallery

BCI - 99%, high purity , CAS No.1245792-51-1

≥99%

CAS#: 1245792-51-1
Formula: C₂₂H₂₃NO
Molecular Weight: 317.42
PubChem CID: 6419844

Item Number

B412799

Grouped product items
SKU	Size	Availability	Price
B412799-5mg	5mg	In stock	$162.90
B412799-25mg	25mg	In stock	$733.90
B412799-50mg	50mg	In stock	$1,320.90
B412799-100mg	100mg	In stock	$2,376.90

phosphatase Inhibitors

View related series

Metabolic Enzyme/Protease Phosphatase

Basic Description

Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	BCI ((E)-BCI, compound 1) is an allosteric dual specificity phosphatase (DUSP) inhibitor with EC50 of 13.3 μM and 8.0 μM in cells for DUSP6 and DUSP1, respectively.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Information BCI BCI ((E)-BCI, compound 1) is an allosteric dual specificity phosphatase (DUSP) inhibitor with EC50 of 13.3 μM and 8.0 μM in cells for DUSP6 and DUSP1, respectively. Targets DUSP1 (Cell-free assay); DUSP6 (Cell-free assay) 8.0 μM(EC50); 13.3 μM(EC50)

Product Properties

ALogP	4.84
HBD Count	1
Rotatable Bond	3

Associated Targets(Human)

DUSP3 Tchem Dual specificity protein phosphatase 3 (1161 Activities)

Discover Target: DUSP3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DUSP5 Tchem Dual specificity protein phosphatase 5 (23 Activities)

Discover Target: DUSP5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Cdc25b Dual specificity phosphatase Cdc25B (32 Activities)

Discover Target: Cdc25b

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Ptpn1 Protein-tyrosine phosphatase 1B (270 Activities)

Discover Target: Ptpn1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Dusp6 Dual specificity protein phosphatase 6 (459 Activities)

Discover Target: Dusp6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Dusp1 Dual specificity protein phosphatase 1 (15 Activities)

Discover Target: Dusp1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Danio rerio (3092 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(2E)-2-benzylidene-3-(cyclohexylamino)-3H-inden-1-one
INCHI	InChI=1S/C22H23NO/c24-22-19-14-8-7-13-18(19)21(23-17-11-5-2-6-12-17)20(22)15-16-9-3-1-4-10-16/h1,3-4,7-10,13-15,17,21,23H,2,5-6,11-12H2/b20-15+
InChi Key	XJDKPLZUXCIMIS-HMMYKYKNSA-N
Canonical SMILES	C1CCC(CC1)NC2C3=CC=CC=C3C(=O)C2=CC4=CC=CC=C4
Isomeric SMILES	C1CCC(CC1)NC\2C3=CC=CC=C3C(=O)/C2=C/C4=CC=CC=C4
PubChem CID	6419844
Molecular Weight	317.42

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot Number	Certificate Type	Date	Item
I2206397	Certificate of Analysis	Jun 18, 2022	B412799
I2206398	Certificate of Analysis	Jun 18, 2022	B412799
I2206399	Certificate of Analysis	Jun 18, 2022	B412799
I2206400	Certificate of Analysis	Jun 18, 2022	B412799

Chemical and Physical Properties

Solubility	Solubility (25°C) In vitro DMSO: 63 mg/mL (198.47 mM); Ethanol: 20 mg/mL (63.0 mM); Water: Insoluble;
DMSO(mg / mL) Max Solubility	63
DMSO(mM) Max Solubility	198.475206351207
Water(mg / mL) Max Solubility	＜1

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.