BCL6-IN-4 - 98%, high purity , CAS No.2253879-65-9

Item Number

B649293

Grouped product items
SKU	Size	Availability	Price
B649293-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$500.90
B649293-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$850.90
B649293-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,800.90
B649293-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,000.90
B649293-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$4,600.90

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Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	BCL6-IN-4 is a potent B-cell lymphoma 6 (BCL6) inhibitor with an IC 50 of 97 nM. BCL6-IN-4 has anti-tumor activities.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	BCL6-IN-4 is a potent B-cell lymphoma 6 (BCL6) inhibitor with an IC 50 of 97 nM. BCL6-IN-4 has anti-tumor activities In Vitro BCL6-IN-4 (compound 25b) inhibits OCI-Ly1 and OCI-Ly3 cell lines growth with GI 50 values of 2.8 μM and 4.2 μM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 97 nM (BCL6)

Associated Targets(Human)

BCL6 Tchem B-cell lymphoma 6 protein (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SUD4 (402 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BCL6 Tchem B-cell lymphoma 6 protein (838 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OCI-Ly1 (107 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OCI-Ly3 (192 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	5-[[5-chloro-2-(2,2,6,6-tetramethylmorpholin-4-yl)pyrimidin-4-yl]amino]-3-(3-hydroxy-3-methylbutyl)-1-methylbenzimidazol-2-one
INCHI	InChI=1S/C25H35ClN6O3/c1-23(2,34)10-11-32-19-12-16(8-9-18(19)30(7)22(32)33)28-20-17(26)13-27-21(29-20)31-14-24(3,4)35-25(5,6)15-31/h8-9,12-13,34H,10-11,14-15H2,1-7H3,(H,27,28,29)
InChi Key	BGCPLWWYPZAURQ-UHFFFAOYSA-N
Canonical SMILES	CC1(CN(CC(O1)(C)C)C2=NC=C(C(=N2)NC3=CC4=C(C=C3)N(C(=O)N4CCC(C)(C)O)C)Cl)C
Isomeric SMILES	CC1(CN(CC(O1)(C)C)C2=NC=C(C(=N2)NC3=CC4=C(C=C3)N(C(=O)N4CCC(C)(C)O)C)Cl)C
PubChem CID	135386972
Molecular Weight	503.04

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Basic Description