BD 1063 dihydrochloride - 98%, high purity , CAS No.206996-13-6

Item Number

B135582

Grouped product items
SKU	Size	Availability	Price
B135582-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$236.90
B135582-50mg	50mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$426.90
B135582-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$768.90
B135582-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,729.90

Selective σ1ligand, putative antagonist

Basic Description

Synonyms	BD 1063 Dihydrochloride\|206996-13-6\|150208-28-9\|BD1063 dhydrochloride\|1-[2-(3,4-Dichlorophenyl)ethyl]-4-methylpiperazine Dihydrochloride\|BD1063 (dhydrochloride)\|BD1063 2HCl\|BD1063\|1-(3,4-dichlorophenethyl)-4-methylpiperazine dihydrochloride\|1-[2-(3,4-dich
Specifications & Purity	98%
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Product Description	Application： BD 1063 dihydrochloride has been used as a sigma-1 receptor (S1R) antagonist: to study the in vitro and in vivo protective action of S1R against ferroptosis in hepatocellular carcinoma cells in a comparative evaluation of its anti-hyperalgesic action with that of the effects of N-(2-morpholin-4-yl-ethyl)-2-(1-naphthyloxy) acetamide (NMIN) in a chronic constriction injury model (CCI) to study the contribution of sigma receptors inhibition to the neuroprotective effects of memantine against amyloid-beta (Aβ)-induced neurotoxicity in SH-SY5Y cells

Names and Identifiers

IUPAC Name	1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine;dihydrochloride
INCHI	InChI=1S/C13H18Cl2N2.2ClH/c1-16-6-8-17(9-7-16)5-4-11-2-3-12(14)13(15)10-11;;/h2-3,10H,4-9H2,1H3;2*1H
InChi Key	NXFDBTLQOARIMH-UHFFFAOYSA-N
Canonical SMILES	CN1CCN(CC1)CCC2=CC(=C(C=C2)Cl)Cl.Cl.Cl
Isomeric SMILES	CN1CCN(CC1)CCC2=CC(=C(C=C2)Cl)Cl.Cl.Cl
WGK Germany	3
PubChem CID	11617161
Molecular Weight	346.12

Certificates

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4 results found

Lot Number	Certificate Type	Date	Item
I2217172	Certificate of Analysis	Jul 17, 2024	B135582
I2217158	Certificate of Analysis	Jul 17, 2024	B135582
I2217168	Certificate of Analysis	Jul 17, 2024	B135582
I2217144	Certificate of Analysis	Jul 17, 2024	B135582

Solubility

Solvent:water, Max Conc. mg/mL: 34.61, Max Conc. mM: 100；H2O: >15 mg/mL

Sensitivity

Moisture sensitive

Melt Point(°C)

>220°C (dec.)

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H319:Causes serious eye irritation
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help.
WGK Germany	3

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Basic Description