Grouped product items

SKU

Size

Availability

Price

Qty

B303771-100mg

100mg

In stock

$58.90

B303771-500mg

500mg

In stock

$265.90

Basic Description

Synonyms	Aminodeoxykanamycin \| Kanamycin B \| Nebramycin V
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Broad spectrum aminoglycoside antibiotic. Binds to 70S ribosomal subunit. Inhibits protein synthesis. Kanamycin A analog. Shows reversible neuromuscular blocking effects in vivo.
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Bacterial 70S ribosome inhibitor
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Bekanamycin is an aminoglycoside antibiotic extracted from Streptomyces kanamyceticus and inhibits a range of Gram positive and negative bacteria.

Product Properties

ALogP	-7.2

Associated Targets(Human)

A549 (127892 Activities)

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HEK293 (82097 Activities)

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Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

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Lypla1 Lysosomal phospholipase A1 (40 Activities)

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Enterococcus (1748 Activities)

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Aspergillus nidulans (364 Activities)

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Pseudomonas aeruginosa (123386 Activities)

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Burkholderia cepacia (649 Activities)

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Pseudomonas fluorescens (1630 Activities)

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Enterobacter cloacae (7976 Activities)

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Klebsiella pneumoniae (43867 Activities)

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Proteus vulgaris (5823 Activities)

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Providencia rettgeri (925 Activities)

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Salmonella typhimurium (15756 Activities)

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Staphylococcus aureus (210822 Activities)

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Staphylococcus epidermidis (22802 Activities)

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Acinetobacter baumannii (41033 Activities)

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Citrobacter freundii (1864 Activities)

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Klebsiella aerogenes (4963 Activities)

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Escherichia coli (133304 Activities)

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Serratia marcescens (3237 Activities)

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Haemophilus influenzae (8812 Activities)

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Enterococcus faecium (13803 Activities)

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Bacillus subtilis (32866 Activities)

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Listeria monocytogenes (2626 Activities)

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Saccharomyces cerevisiae (19171 Activities)

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Enterococcus faecalis (29875 Activities)

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Mycolicibacterium smegmatis (8003 Activities)

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Candida albicans (78123 Activities)

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Fusarium oxysporum (3998 Activities)

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Rhodotorula mucilaginosa (339 Activities)

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Salmonella enterica (1497 Activities)

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NIH3T3 (5395 Activities)

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fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 (47 Activities)

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Bacillus spizizenii (1898 Activities)

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Fusarium graminearum (1554 Activities)

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SARS-CoV-2 (38078 Activities)

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Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4-diol
INCHI	InChI=1S/C18H37N5O10/c19-2-6-11(26)12(27)9(23)17(30-6)32-15-4(20)1-5(21)16(14(15)29)33-18-13(28)8(22)10(25)7(3-24)31-18/h4-18,24-29H,1-3,19-23H2/t4-,5+,6+,7+,8-,9+,10+,11+,12+,13+,14-,15+,16-,17+,18+/m0/s1
InChi Key	SKKLOUVUUNMCJE-FQSMHNGLSA-N
Canonical SMILES	C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)N)N
Isomeric SMILES	C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)N)N
PubChem CID	439318
Molecular Weight	483.51

Database links

Antibiotic DB	1856
PubChem CID	439318
ChEMBL Ligand	CHEMBL176
ChEBI	CHEBI:28098
DrugBank Ligand	DB13673
DrugCentral Ligand	1520
RCSB PDB Ligand	9CS
CAS Registry No.	4696-76-8

Certificates

Certificate of Analysis(COA)

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Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot Number	Certificate Type	Date	Item
H2131017	Certificate of Analysis	Jun 12, 2024	B303771
G2312296	Certificate of Analysis	Jun 17, 2023	B303771
G2312301	Certificate of Analysis	Jun 17, 2023	B303771
G2312305	Certificate of Analysis	Jun 17, 2023	B303771
G2312314	Certificate of Analysis	Jun 17, 2023	B303771
K2222415	Certificate of Analysis	Mar 22, 2021	B303771

Chemical and Physical Properties

Sensitivity	Moisture sensitive

References

1. Cron MJ, Fardig OB, Johnson DL, Palermiti FM, Schmitz H, Hooper IR. (1958) The chemistry of kanamycin.. Ann N Y Acad Sci, 76 (2): (27-30). [PMID:13595490] [10.1021/op500134e]
2. Price KE. (1986) The potential for discovery and development of improved aminoglycosides.. Am J Med, 80 (6B): (182-9). [PMID:3089002] [10.1021/op500134e]

Solution Calculators

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Bekanamycin - >98%, high purity , Bacterial 70S ribosome inhibitor, CAS No.4696-76-8, Bacterial 70S ribosome inhibitor

Basic Description

Product Properties

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Related Documents

References

Solution Calculators

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Dilution Calculator

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