Bekanamycin - >98%, high purity , Bacterial 70S ribosome inhibitor, CAS No.4696-76-8, Bacterial 70S ribosome inhibitor

Item Number
B303771
Grouped product items
SKUSizeAvailabilityPrice Qty
B303771-100mg
100mg
In stock
$58.90
B303771-500mg
500mg
In stock
$265.90

Broad spectrum aminoglycoside antibiotic

View related series
Antibiotic Bacterial

Basic Description

Synonymsbekanamycin | Kanamycin B | 4696-76-8 | Nebramycin V | Aminodeoxykanamycin | nebramycin factor 5 | Bekanamycin [INN] | 2'-Amino-2'-deoxykanamycin | Klebcil | NK 1006 | NK-1006 | 15JT14C3GI | DTXSID8023185 | CHEBI:28098 | Bekanamycin (INN) | (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsBroad spectrum aminoglycoside antibiotic. Binds to 70S ribosomal subunit. Inhibits protein synthesis. Kanamycin A analog. Shows reversible neuromuscular blocking effects in vivo.
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionBacterial 70S ribosome inhibitor
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Bekanamycin is an aminoglycoside antibiotic extracted from Streptomyces kanamyceticus and inhibits a range of Gram positive and negative bacteria.

Product Properties

ALogP-7.2

Associated Targets(Human)

A549 127892 Activities

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HEK293 82097 Activities

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Associated Targets(non-human)

Histone deacetylase 6 222 Activities

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Lysosomal phospholipase A1 40 Activities

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Enterococcus 1748 Activities

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Aspergillus nidulans 364 Activities

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Pseudomonas aeruginosa 123386 Activities

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Burkholderia cepacia 649 Activities

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Pseudomonas fluorescens 1630 Activities

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Enterobacter cloacae 7976 Activities

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Klebsiella pneumoniae 43867 Activities

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Proteus vulgaris 5823 Activities

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Providencia rettgeri 925 Activities

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Salmonella typhimurium 15756 Activities

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Staphylococcus aureus 210822 Activities

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Staphylococcus epidermidis 22802 Activities

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Acinetobacter baumannii 41033 Activities

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Citrobacter freundii 1864 Activities

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Klebsiella aerogenes 4963 Activities

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Escherichia coli 133304 Activities

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Serratia marcescens 3237 Activities

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Haemophilus influenzae 8812 Activities

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Enterococcus faecium 13803 Activities

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Bacillus subtilis 32866 Activities

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Listeria monocytogenes 2626 Activities

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Saccharomyces cerevisiae 19171 Activities

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Enterococcus faecalis 29875 Activities

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Mycolicibacterium smegmatis 8003 Activities

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Candida albicans 78123 Activities

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Fusarium oxysporum 3998 Activities

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Rhodotorula mucilaginosa 339 Activities

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Salmonella enterica 1497 Activities

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NIH3T3 5395 Activities

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3-oxoacyl-[acyl-carrier-protein] synthase 3 47 Activities

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Bacillus spizizenii 1898 Activities

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Fusarium graminearum 1554 Activities

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SARS-CoV-2 38078 Activities

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Bacillus amyloliquefaciens 102 Activities

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Names and Identifiers

IUPAC Name (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4-diol
INCHI InChI=1S/C18H37N5O10/c19-2-6-11(26)12(27)9(23)17(30-6)32-15-4(20)1-5(21)16(14(15)29)33-18-13(28)8(22)10(25)7(3-24)31-18/h4-18,24-29H,1-3,19-23H2/t4-,5+,6+,7+,8-,9+,10+,11+,12+,13+,14-,15+,16-,17+,18+/m0/s1
InChi Key SKKLOUVUUNMCJE-FQSMHNGLSA-N
Canonical SMILES C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)N)N
Isomeric SMILES C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)N)N
PubChem CID 439318
Molecular Weight 483.51

Certificates

Certificate of Analysis(COA)

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6 results found

Lot NumberCertificate TypeDateItem
H2131017Certificate of AnalysisJun 12, 2024 B303771
G2312296Certificate of AnalysisJun 17, 2023 B303771
G2312301Certificate of AnalysisJun 17, 2023 B303771
G2312305Certificate of AnalysisJun 17, 2023 B303771
G2312314Certificate of AnalysisJun 17, 2023 B303771
K2222415Certificate of AnalysisMar 22, 2021 B303771

Chemical and Physical Properties

SensitivityMoisture sensitive

Related Documents

References

1. Cron MJ, Fardig OB, Johnson DL, Palermiti FM, Schmitz H, Hooper IR.  (1958)  The chemistry of kanamycin..  Ann N Y Acad Sci,  76  (2): (27-30).  [PMID:13595490]
2. Price KE.  (1986)  The potential for discovery and development of improved aminoglycosides..  Am J Med,  80  (6B): (182-9).  [PMID:3089002]

Solution Calculators