Bemarituzumab (anti-FGFR2) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to FGFR2, >95%, high purity, Human IgG1, Antibody of Fc fragment of IgG receptor IIIa;Antibody of fibroblast growth factor receptor 2

Features and benefits
  • Short Overview:

    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

  • Application: ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
  • Species reactivity(Reacts with): Cynomolgus monkey,Human,Mouse
  • Isotype: Human IgG1
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
Item Number
Ab170514
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab170514-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
Ab170514-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$240.90
Ab170514-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$588.90
Ab170514-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$987.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product NameBemarituzumab (anti-FGFR2) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to FGFR2, >95%, high purity, Human IgG1
SynonymsEC 2.7.10.1 | FGFR-2 | Keratinocyte growth factor receptor | KGFR | K-sam
Specifications & PurityExactAb™, Validated, Carrier Free, Low Endotoxin, Azide Free, Recombinant, ≥95%(SDS-PAGE&SEC)
SpecificityFGFR2
ApplicationELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Positive ControlLot by Lot
ConjugationUnconjugated
GradeAzide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action TypeANTAGONIST
Mechanism of actionAntibody of Fc fragment of IgG receptor IIIa;Antibody of fibroblast growth factor receptor 2
Product Description

Bemarituzumab (anti-FGFR2) is a recombinant monoclonal antibody against FGFR2b (a FGF receptor). Bemarituzumab blocks fibroblast growth factors from binding and activating FGFR2b. Bemarituzumab has the potential for cancer research.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Antibody TypePrimary antibody
ClonalityRecombinant
IsotypeHuman IgG1
Light Chain Typekappa
SDS-PAGE26.5 kDa (Light Chain) & 50.6 kDa (Heavy Chain), under reducing conditions; 171.4 kDa, under non-reducing conditions.
Purity>95%
SourceCHO supernatant
FormLiquid
Storage TempStore at -80°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
CAS1952272-74-0

Images

Bemarituzumab (anti-FGFR2) (Ab170514) - SEC
The purity of Bemarituzumab (anti-FGFR2) (Ab170514) is more than 95% verified by HPLC.

Bemarituzumab (anti-FGFR2) (Ab170514) - ELISA
Immobilized hu-FGFR2-β-IIIb-ECD-His 2 μg/mL can bind Bemarituzumab (anti-FGFR2) (Ab170514) with the EC₅₀ of 13.35 ng/mL.


Associated Targets(Human)

FGFR2 Tclin Fibroblast growth factor receptor 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FCGR3A Tclin Low affinity immunoglobulin gamma Fc region receptor III-A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FGFR2 Tclin Fibroblast growth factor receptor 2 (3405 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FCGR3A Tclin Low affinity immunoglobulin gamma Fc region receptor III-A (0 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FGFR2 Tclin Cereblon/FGFR2 (3 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Certificates

Certificate of Analysis(COA)

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Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
ZJ23F0901133Certificate of AnalysisSep 24, 2023 Ab170514
ZJ23F0901132Certificate of AnalysisSep 24, 2023 Ab170514

Related Documents

References

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