Benserazide hydrochloride - 98%, high purity , CAS No.14919-77-8

Item Number

B101489

• Synonyms: HMS1570L18 | CHEBI:31262 | SB44383 | SCHEMBL364720 | Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide, hydrochloride (1:1) | SR-01000003044 | CAS-14919-77-8 | FT-0760799 | 2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride | 2-
• Specifications & Purity: ≥98%
• Biochemical and Physiological Mechanisms: Benserazide can block HK2 enzymatic activity in vitro. It is used along with levodopa to treat Parkinson′s disease.Peripherally acting DOPA decarboxylase inhibitor. Increases the cerebral availability of L-DOPA. Increases GDNF levels in infarction sites.
• Storage Temp: Store at 2-8°C,Argon charged
• Shipped In: Wet ice
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Benserazide is a peripheral decarboxylase inhibitor

Benserazide has been used:

· to inhibit dopa-decarboxylase

· to induce dyskinesia

· to test on purified bacterial TDCs to assess the extent to which it could affect bacterial decarboxylases

· as a peripheral dopa decarboxylase inhibitor to treat mice