Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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B423602-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 |
Synonyms | benzbromarone | 3562-84-3 | Benzbromaron | Desuric | Urinorm | Normurat | Uricovac | Minuric | Exurate | Hipurik | Azubromaron | Narcaricin | L 2214-Labaz | MJ 10061 | Uroleap (TN) | Methanone, (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)- | Uroleap | 3,5-Dibromo-4-hydroxyphenyl- |
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Specifications & Purity | 10mM in DMSO |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
ALogP | 5.7 |
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IUPAC Name | (3,5-dibromo-4-hydroxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone |
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INCHI | InChI=1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3 |
InChi Key | WHQCHUCQKNIQEC-UHFFFAOYSA-N |
Canonical SMILES | CCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)Br)O)Br |
Isomeric SMILES | CCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)Br)O)Br |
WGK Germany | 3 |
RTECS | OB1804200 |
PubChem CID | 2333 |
Molecular Weight | 424.08 |
Reaxy-Rn | 273668 |
Enter Lot Number to search for COA:
Melt Point(°C) | 152 °C |
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Pictogram(s) | GHS06, GHS08, GHS09 |
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Signal | Danger |
Hazard Statements | H301:Toxic if swallowed H411:Toxic to aquatic life with long lasting effects H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P391:Collect spillage. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P318:if exposed or concerned, get medical advice. |
WGK Germany | 3 |
RTECS | OB1804200 |
Reaxy-Rn | 273668 |
Merck Index | 1065 |
1. Lin Xiang, Yuting Huang, Rong Li, Yexing Tao, Ting Wu, Siyi Pan, Xiaoyun Xu. (2023) Artemisia selengensis Turcz. leaves extract ameliorates hyperuricemia in mice by inhibiting hepatic xanthine oxidase activity, modulating renal uric acid transporters, and improving metabolic disorders. Food Bioscience, (102639). [PMID:] |
2. Jian Gao, Hao Yin, Yanqun Dong, Xintong Wang, Yani Liu, KeWei Wang. (2023) A Novel Role of Uricosuric Agent Benzbromarone in BK Channel Activation and Reduction of Airway Smooth Muscle Contraction. MOLECULAR PHARMACOLOGY, 103 (4): (241-254). [PMID:36669879] |
3. Tianqiao Yong, Danling Liang, Chun Xiao, Longhua Huang, Shaodan Chen, Yizhen Xie, Xiong Gao, Qingping Wu, Huiping Hu, Xiangmin Li, Yuancao Liu, Manjun Cai. (2022) Hypouricemic effect of 2,4-dihydroxybenzoic acid methyl ester in hyperuricemic mice through inhibiting XOD and down-regulating URAT1. BIOMEDICINE & PHARMACOTHERAPY, 153 (113303). [PMID:35750011] |
4. Ze-Rui Sun, Hua-Rong Liu, Di Hu, Mao-Si Fan, Ming-Yue Wang, Meng-Fei An, Yun-Li Zhao, Ze-Min Xiang, Jun Sheng. (2021) Ellagic Acid Exerts Beneficial Effects on Hyperuricemia by Inhibiting Xanthine Oxidase and NLRP3 Inflammasome Activation. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 69 (43): (12741–12752). [PMID:34672194] |
1. Lin Xiang, Yuting Huang, Rong Li, Yexing Tao, Ting Wu, Siyi Pan, Xiaoyun Xu. (2023) Artemisia selengensis Turcz. leaves extract ameliorates hyperuricemia in mice by inhibiting hepatic xanthine oxidase activity, modulating renal uric acid transporters, and improving metabolic disorders. Food Bioscience, (102639). [PMID:] |
2. Jian Gao, Hao Yin, Yanqun Dong, Xintong Wang, Yani Liu, KeWei Wang. (2023) A Novel Role of Uricosuric Agent Benzbromarone in BK Channel Activation and Reduction of Airway Smooth Muscle Contraction. MOLECULAR PHARMACOLOGY, 103 (4): (241-254). [PMID:36669879] |
3. Tianqiao Yong, Danling Liang, Chun Xiao, Longhua Huang, Shaodan Chen, Yizhen Xie, Xiong Gao, Qingping Wu, Huiping Hu, Xiangmin Li, Yuancao Liu, Manjun Cai. (2022) Hypouricemic effect of 2,4-dihydroxybenzoic acid methyl ester in hyperuricemic mice through inhibiting XOD and down-regulating URAT1. BIOMEDICINE & PHARMACOTHERAPY, 153 (113303). [PMID:35750011] |
4. Ze-Rui Sun, Hua-Rong Liu, Di Hu, Mao-Si Fan, Ming-Yue Wang, Meng-Fei An, Yun-Li Zhao, Ze-Min Xiang, Jun Sheng. (2021) Ellagic Acid Exerts Beneficial Effects on Hyperuricemia by Inhibiting Xanthine Oxidase and NLRP3 Inflammasome Activation. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 69 (43): (12741–12752). [PMID:34672194] |