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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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B607993-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $46.90 | |
B607993-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $79.90 | |
B607993-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $159.90 | |
B607993-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $246.90 | |
B607993-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $359.90 |
Synonyms | 5-(benzenesulfonamido)-1,3,4-thiadiazole-2-sulfonamide | BDBM10886 | 2-N-benzene-1,3,4-thiadiazole-2,5-disulfonamide | AS-78505 | HY-118467 | 1,3,4-Thiadiazole-2-sulfonamide, 5-benzenesulfonamido- | 2-benzenesulfonamido-1,3,4-thiadiazole-5-sulfonamide | D |
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Specifications & Purity | Moligand™, ≥98% |
Storage Temp | Store at 2-8°C,Protected from light |
Shipped In | Wet ice |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of carbonic anhydrase 1;Inhibitor of carbonic anhydrase 12 |
Product Description | Benzolamide (CL11366) is a potent carbonic anhydrase (CA) inhibitor, with Kis of 15 nM, 9 nM, 94 nM and 78 nM for hCA I, hCA II, EcoCAγ and VchCAγ, respectively. Benzolamide also inhibits CAS3, with a Ki of 54 nM. Benzolamide can be used for the research of glaucoma and seizures |
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IUPAC Name | 5-(benzenesulfonamido)-1,3,4-thiadiazole-2-sulfonamide |
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INCHI | InChI=1S/C8H8N4O4S3/c9-18(13,14)8-11-10-7(17-8)12-19(15,16)6-4-2-1-3-5-6/h1-5H,(H,10,12)(H2,9,13,14) |
InChi Key | PWDGTQXZLNDOKS-UHFFFAOYSA-N |
Canonical SMILES | C1=CC=C(C=C1)S(=O)(=O)NC2=NN=C(S2)S(=O)(=O)N |
Isomeric SMILES | C1=CC=C(C=C1)S(=O)(=O)NC2=NN=C(S2)S(=O)(=O)N |
PubChem CID | 18794 |
Molecular Weight | 320.37 |
PubChem CID | 18794 |
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ChEMBL Ligand | CHEMBL73962 |
CAS Registry No. | 3368-13-6 |
RCSB PDB Ligand | D8W |
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Solubility | DMSO: 250 mg/mL (780.35 mM) |
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Sensitivity | light sensitive |