JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

྾

Home
Applications
Targets
Enzymes
Peptidases and proteinases
benzyl N-[(2S)-1-[[4-[3-(6-aminopurin-9-yl)propylamino]-3,4-dioxo-1-phenylbutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate , CAS No.B609316, Inhibitor of calpain 2

Skip to the end of the images gallery

Skip to the beginning of the images gallery

benzyl N-[(2S)-1-[[4-[3-(6-aminopurin-9-yl)propylamino]-3,4-dioxo-1-phenylbutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate , CAS No.B609316, Inhibitor of calpain 2

Moligand™

PubChem CID: 46930721

Item Number

B609316

Grouped product items
SKU	Size	Availability	Price	Qty
B609316-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$700.90
B609316-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

calpain 2 Inhibitor

Basic Description

Synonyms	Cbz-Leu-D,L-Phe-CONH-(CH(2))(3)-adenin-9-yl;compound 5a
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of calpain 2

Associated Targets(Human)

CAPN2 Tchem Calpain-2 catalytic subunit (0 Activities)

Discover Target: CAPN2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CTSB Tchem Cathepsin B (3822 Activities)

Discover Target: CTSB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CAPN2 Tchem Calpain 2 (185 Activities)

Discover Target: CAPN2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

CAPN1 Calpain 1 (219 Activities)

Discover Target: CAPN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	benzyl N-[(2S)-1-[[4-[3-(6-aminopurin-9-yl)propylamino]-3,4-dioxo-1-phenylbutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate
INCHI	InChI=1S/C32H38N8O5/c1-21(2)16-25(39-32(44)45-18-23-12-7-4-8-13-23)30(42)38-24(17-22-10-5-3-6-11-22)27(41)31(43)34-14-9-15-40-20-37-26-28(33)35-19-36-29(26)40/h3-8,10-13,19-21,24-25H,9,14-18H2,1-2H3,(H,34,43)(H,38,42)(H,39,44)(H2,33,35,36)/t24?,25-/m0/s1
InChi Key	OVLNPOAZKHQAAD-BBMPLOMVSA-N
Canonical SMILES	CC(C[C@@H](C(=O)NC(C(=O)C(=O)NCCCn1cnc2c1ncnc2N)Cc1ccccc1)NC(=O)OCc1ccccc1)C
Isomeric SMILES	CC(C)C[C@@H](C(=O)NC(CC1=CC=CC=C1)C(=O)C(=O)NCCCN2C=NC3=C(N=CN=C32)N)NC(=O)OCC4=CC=CC=C4
PubChem CID	46930721

Database links

PubChem CID	46930721
ChEMBL Ligand	CHEMBL1240872

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

References

1. Ovat A, Li ZZ, Hampton CY, Asress SA, Fernández FM, Glass JD, Powers JC. (2010) Peptidyl alpha-ketoamides with nucleobases, methylpiperazine, and dimethylaminoalkyl substituents as calpain inhibitors.. J Med Chem, 53 (17): (6326-36). [PMID:20690647]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.