Bestatin - ≥97%, high purity , CAS No.58970-76-6, Inhibitor of Leucine aminopeptidase 3;Inhibitor of Leukotriene A 4 hydrolase

Item Number

B165318

• Synonyms: (3-Amino-2-hydroxy-4-phenylbutanoyl)-L-leucine | UBENIMEX [WHO-DD] | 4-methyl-pyrimidin-2-ylamine | L-Leucine, N-[(2S,3R)-3-amino-2-hydroxy-1-oxo-4-phenylbutyl]- | KBioGR_000273 | N-[(2S,3R)-3-Amino-2-hydroxy-1-oxo-4-phenylbutyl]-L-leucine | SMR000059165
• Specifications & Purity: Moligand™, ≥97%
• Biochemical and Physiological Mechanisms: Potent, competitive aminopeptidase inhibitor (IC 50 values are 20 and 60 nM for leucine aminopeptidase and aminopeptidase B, respectively). Inhibits leukotriene A 4 hydrolase and tumor cell proliferation. Shows immunomodulatory effects in vivo.
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Inhibitor of Leucine aminopeptidase 3;Inhibitor of Leukotriene A 4 hydrolase
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

A competitive inhibitor of aminopeptidases, especially aminopeptidase B, leucine aminopeptidase and tripeptide aminopeptidase. Not an inhibitor of carboxypeptidases.