beta-Secretase Inhibitor II (Z-VLL-CHO) - ≥95%, high purity , CAS No.263563-09-3

Item Number

S276273

• Synonyms: benzylN-[(2S)-3-methyl-1-[[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxobutan-2-yl]carbamate
• Specifications & Purity: ≥95%
• Biochemical and Physiological Mechanisms: Cell-permeable, reversible β-secretase inhibitor. Corresponds to the VNL-DA cleavage site on APP. Inhibits Aβ formation (IC 50 values are 0.7 and 2.5 µM for Aβtotal and Aβ1-42 respectively). Shows neuroprotective effects.
• Storage Temp: Protected from light,Store at -20°C,Desiccated
• Shipped In: Ice chest + Ice pads
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.