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Betaxolol - ≥98%, high purity , CAS No.63659-18-7, Antagonist of β 1-adrenoceptor;Antagonist of β 2-adrenoceptor
Basic Description
| Synonyms | 1-{4-[2-(Cyclopropylmethoxy)ethyl]phenoxy}-3-[(propan-2-yl)amino]propan-2-ol | NCGC00015159-04 | C75987 | D07526 | NCGC00015159-06 | C07AB05 | GTPL549 | HMS3884L05 | AS-14125 | SCHEMBL23530 | (.+/-.)-1-[p-[2-(Cyclopropylmethoxy)ethyl]phenoxy]-3-(isopropyl |
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| Specifications & Purity | Moligand™, ≥98% |
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| Biochemical and Physiological Mechanisms | Betaxolol is a cardioselective β1-adrenergic blocker, as well as an antihypertensive and an antiglaucoma |
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| Storage Temp | Store at -20°C |
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| Shipped In | Ice chest + Ice pads |
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| Grade | Moligand™ |
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| Action Type | ANTAGONIST |
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| Mechanism of action | Antagonist of β 1-adrenoceptor;Antagonist of β 2-adrenoceptor |
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| Note | 250mg、10mg卖完停产，不再备货 |
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| Product Description | Betaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma |
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Associated Targets(Human)
Associated Targets(non-human)
Names and Identifiers
| Pubchem Sid | 488179698 |
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| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179698 |
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| IUPAC Name | 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol |
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| INCHI | InChI=1S/C18H29NO3/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3 |
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| InChi Key | NWIUTZDMDHAVTP-UHFFFAOYSA-N |
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| Canonical SMILES | CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O |
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| Isomeric SMILES | CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O |
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| PubChem CID | 2369 |
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| Molecular Weight | 307.43 |
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Chemical and Physical Properties
| Solubility | Soluble in Acetone and Chloroform |
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| Melt Point(°C) | 61-63°C |
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Safety and Hazards(GHS)
| Pictogram(s) | GHS08, GHS07 |
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| Signal | Warning |
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| Hazard Statements | H412:Harmful to aquatic life with long lasting effects H302:Harmful if swallowed H361:Suspected of damaging fertility or the unborn child |
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| Precautionary Statements | P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. |
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