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Bezafibrate - ≥98%, high purity , Peroxisome proliferator-activated receptor agonist, CAS No.41859-67-0, Peroxisome proliferator-activated receptor agonist

12 Citations

Moligand™

≥98%

CAS#: 41859-67-0
Formula: C₁₉H₂₀ClNO₄
Molecular Weight: 361.82
EC Number: 255-567-9
MDL number: MFCD00078970
PubChem CID: 39042

Item Number

B129520

Grouped product items
SKU	Size	Availability	Price
B129520-1g	1g	In stock	$25.90
B129520-5g	5g	In stock	$98.90
B129520-10g	10g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$177.90
B129520-25g	25g	In stock	$217.90
B129520-100g	100g	In stock	$783.90
B129520-500g	500g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,524.90

Pan-PPAR agonist

View related series

Peroxisome proliferator-activated receptor-α Agonist

Basic Description

Synonyms	Bezafibrate [USAN:INN:BAN:JAN] \| Difaterol \| MLS001148205 \| Opera_ID_376 \| PEM \| 2-[P-[2-P-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPIONIC ACID \| Bezalip Retard \| BM15075 \| BM-15075 \| KBio2_007059 \| Regadrin B \| BEZAFIBRATE (EP MONOGRAPH) \| Bezamerck \| P
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Bezafibrate is a peroxisome proliferator and hypolipidaemic agent that is a derivative of clofibrate. Shown to be effective in preventing mammary tumors induced by radiation together with DES, possibly by reducing prolactin and triglyceride concentrations
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Peroxisome proliferator-activated receptor agonist
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Bezafibrate is the first clinically tested dual and pan-PPAR co-agonism. A peroxisome proliferator and hypolipidaemic agent.

Product Properties

ALogP	3.8

Associated Targets(Human)

PPARA Tclin Peroxisome proliferator-activated receptor alpha (1 Activities)

Discover Target: PPARA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PDE5A Tclin Phosphodiesterase 5A (5113 Activities)

Discover Target: PDE5A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)

Discover Target: EGFR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CA2 Tclin Carbonic anhydrase II (17698 Activities)

Discover Target: CA2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ESR1 Tclin Estrogen receptor alpha (17718 Activities)

Discover Target: ESR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HMGCR Tclin HMG-CoA reductase (2475 Activities)

Discover Target: HMGCR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

Discover Target: NR3C1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

INSR Tclin Insulin receptor (5558 Activities)

Discover Target: INSR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PGR Tclin Progesterone receptor (8562 Activities)

Discover Target: PGR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)

Discover Target: ADRB2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)

Discover Target: CHRM2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)

Discover Target: ADRB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)

Discover Target: HTR1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)

Discover Target: ADRA2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

Discover Target: CHRM1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACE Tclin Angiotensin-converting enzyme (1423 Activities)

Discover Target: ACE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD2 Tclin Dopamine D2 receptor (23596 Activities)

Discover Target: DRD2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)

Discover Target: GABRA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAOA Tclin Monoamine oxidase A (11911 Activities)

Discover Target: MAOA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)

Discover Target: CNR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD1 Tclin Dopamine D1 receptor (9720 Activities)

Discover Target: DRD1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD4 Tchem Dopamine D4 receptor (7907 Activities)

Discover Target: DRD4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)

Discover Target: PTGS1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A2 Tclin Norepinephrine transporter (10102 Activities)

Discover Target: SLC6A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HRH2 Tclin Histamine H2 receptor (5428 Activities)

Discover Target: HRH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)

Discover Target: ADRA1D

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)

Discover Target: HTR1B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)

Discover Target: HTR2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)

Discover Target: HTR2C

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AVPR2 Tclin Vasopressin V2 receptor (2912 Activities)

Discover Target: AVPR2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADORA1 Tclin Adenosine A1 receptor (17603 Activities)

Discover Target: ADORA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)

Discover Target: AGTR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CALCR Tclin Calcitonin receptor (2215 Activities)

Discover Target: CALCR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A4 Tclin Serotonin transporter (12625 Activities)

Discover Target: SLC6A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)

Discover Target: ADRA1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)

Discover Target: PTGS2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HRH1 Tclin Histamine H1 receptor (7573 Activities)

Discover Target: HRH1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)

Discover Target: ADRA1B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRM1 Tclin Mu opioid receptor (19785 Activities)

Discover Target: OPRM1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD3 Tclin Dopamine D3 receptor (14368 Activities)

Discover Target: DRD3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)

Discover Target: PPARG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)

Discover Target: AVPR1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRD1 Tclin Delta opioid receptor (15096 Activities)

Discover Target: OPRD1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRK1 Tclin Kappa opioid receptor (16155 Activities)

Discover Target: OPRK1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR3A Tclin Serotonin 3a (5-HT3a) receptor (3366 Activities)

Discover Target: HTR3A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A3 Tclin Dopamine transporter (10535 Activities)

Discover Target: SLC6A3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GRIN1 Tclin Glutamate (NMDA) receptor subunit zeta 1 (122 Activities)

Discover Target: GRIN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PPARA Tclin Peroxisome proliferator-activated receptor alpha (9197 Activities)

Discover Target: PPARA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KCNH2 Tclin HERG (29587 Activities)

Discover Target: KCNH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)

Discover Target: Agtr2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mc4r Melanocortin receptor 4 (1205 Activities)

Discover Target: Mc4r

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Ltc4s Leukotriene C4 synthase (1 Activities)

Discover Target: Ltc4s

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Sigmar1 Sigma opioid receptor (160 Activities)

Discover Target: Sigmar1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Ttr Transthyretin (14 Activities)

Discover Target: Ttr

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Npy1r Neuropeptide Y receptor type 1 (8 Activities)

Discover Target: Npy1r

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cckar Cholecystokinin A receptor (90 Activities)

Discover Target: Cckar

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pde4d Phosphodiesterase 4D (4 Activities)

Discover Target: Pde4d

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Ppard Peroxisome proliferator-activated receptor delta (358 Activities)

Discover Target: Ppard

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nos2 Nitric oxide synthase, inducible (3573 Activities)

Discover Target: Nos2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mapk1 MAP kinase ERK2 (650 Activities)

Discover Target: Mapk1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mmp9 Matrix metalloproteinase 9 (38 Activities)

Discover Target: Mmp9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Saccharomyces cerevisiae (19171 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Luciferin 4-monooxygenase (66902 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasma (328 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)

Discover Target: ffp

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Glra2 Glycine receptor (1745 Activities)

Discover Target: Glra2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic acid
INCHI	InChI=1S/C19H20ClNO4/c1-19(2,18(23)24)25-16-9-3-13(4-10-16)11-12-21-17(22)14-5-7-15(20)8-6-14/h3-10H,11-12H2,1-2H3,(H,21,22)(H,23,24)
InChi Key	IIBYAHWJQTYFKB-UHFFFAOYSA-N
Canonical SMILES	CC(C)(C(=O)O)OC1=CC=C(C=C1)CCNC(=O)C2=CC=C(C=C2)Cl
Isomeric SMILES	CC(C)(C(=O)O)OC1=CC=C(C=C1)CCNC(=O)C2=CC=C(C=C2)Cl
WGK Germany	1
RTECS	UE8755000
PubChem CID	39042
Molecular Weight	361.82
Reaxy-Rn	4267656

Database links

PubChem CID	39042
DrugBank Ligand	DB01393
CAS Registry No.	41859-67-0
ChEBI	CHEBI:47612
ChEMBL Ligand	CHEMBL264374
BindingDB Ligand	28701
Wikipedia	Bezafibrate
NURSA Ligand	10.1621/N2ZUHQHU9O
RCSB PDB Ligand	PEM
PEP	bezafibrate
DrugCentral Ligand	362

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot Number	Certificate Type	Date	Item
I2209211	Certificate of Analysis	Jun 05, 2024	B129520
I2209212	Certificate of Analysis	Jun 05, 2024	B129520
I2209213	Certificate of Analysis	Jun 05, 2024	B129520
I2209214	Certificate of Analysis	Jun 05, 2024	B129520
L1713093	Certificate of Analysis	May 11, 2023	B129520
K1708028	Certificate of Analysis	Apr 14, 2023	B129520
D2114443	Certificate of Analysis	Jan 17, 2023	B129520
D2114447	Certificate of Analysis	Jan 17, 2023	B129520
D2114450	Certificate of Analysis	Jan 17, 2023	B129520
I2319044	Certificate of Analysis	Jul 22, 2022	B129520

Chemical and Physical Properties

Solubility	Soluble in DMSO (50 mg/ml), water (partly), methanol, ethanol (~3 mg/ml), and DMF (~30 mg/ml).
Melt Point(°C)	183-186°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice.
WGK Germany	1
RTECS	UE8755000
Reaxy-Rn	4267656
Merck Index	1195

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Huimin Zhou, Zhiwei Qiu, Jin Zeng, Ruobin Dai, Zhiwei Wang. (2023) Ultra-permeable polyamide nanofiltration membrane modified by hydrophilic-hydrophobic alternated lignocellulosic nanofibrils for efficient water reuse. JOURNAL OF MEMBRANE SCIENCE, 688 (15): (122125). [PMID:10677542] [10.1016/j.memsci.2023.122125]
2. Xuecong Qian, Shilong Wang, Haijun Cheng, Ziye Jia, Da Wang, Yandong Xie, Jinhao Duan, Yu Tian, Jun Ma. (2023) Mn(II) oxidation by the UV/chlorine system under near-neutral pH conditions: The important role of ClO· and ClO2. WATER RESEARCH, 246 (28): (120673). [PMID:37844341] [10.1016/j.watres.2023.120673]
3. Mingming Qi, Hui Zhong, Zhaoyan Cheng, Shujie Chen, Han Xiao, Jing Shang, Li Chen, Jianbo Sun. (2023) Discovery of NAFLD-Improving Agents by Promoting the Degradation of Keap1. JOURNAL OF MEDICINAL CHEMISTRY, [PMID:37386884] [10.1021/acs.jmedchem.3c00822]
4. Tianhua He, Nikita Lykov, Xu Luo, Huiling Wang, Zhanxiang Du, Ziyi Chen, Shitian Chen, Lin Zhu, Ye Zhao, Chimeng Tzeng. (2023) Protective Effects of Lactobacillus gasseri against High-Cholesterol Diet-Induced Fatty Liver and Regulation of Host Gene Expression Profiles. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (3): (2053). [PMID:36768377] [10.3390/ijms24032053]
5. Ji Ma, Yang Deng, Tingting Yang, Maoru Li, Jing Shang. (2023) Esculetin Alleviates Nonalcoholic Fatty Liver Disease on High-Cholesterol-Diet-Induced Larval Zebrafish and FFA-Induced BRL-3A Hepatocyte. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (2): (1593). [PMID:36675107] [10.3390/ijms24021593]
6. Hui Su, Xudan Dou, Dandan Xu, Li Feng, Yongze Liu, Ziwen Du, Liqiu Zhang. (2022) Fe0-loaded superfine powdered activated carbon prepared by ball milling for synergistic adsorption and persulfate activation to remove aqueous carbamazepine. CHEMOSPHERE, 293 (133665). [PMID:35051510] [10.1016/j.chemosphere.2022.133665]
7. Xiangyu Chen, Juanjuan Yao, Hongsen Dong, Mingjian Hong, Naiyun Gao, Zhi Zhang, Wenchao Jiang. (2021) Enhanced bezafibrate degradation and power generation via the simultaneous PMS activation in visible light photocatalytic fuel cell. WATER RESEARCH, 207 (117800). [PMID:34741902] [10.1016/j.watres.2021.117800]
8. Yang Deng, Ji Ma, Xin Weng, Yuqin Wang, Maoru Li, Tingting Yang, Zhiyang Dou, Zhiqi Yin, Jing Shang. (2021) Kaempferol-3-O-Glucuronide Ameliorates Non-Alcoholic Steatohepatitis in High-Cholesterol-Diet-Induced Larval Zebrafish and HepG2 Cell Models via Regulating Oxidation Stress. Life-Basel, 11 (5): (445). [PMID:34069176] [10.3390/life11050445]
9. Yang Guo, Erzhuo Zhao, Jun Wang, Xiaoyuan Zhang, Haiou Huang, Gang Yu, Yujue Wang. (2020) Comparison of emerging contaminant abatement by conventional ozonation, catalytic ozonation, O3/H2O2 and electro-peroxone processes. JOURNAL OF HAZARDOUS MATERIALS, 389 (121829). [PMID:31836369] [10.1016/j.jhazmat.2019.121829]
10. Nadeem Muhammad, Dandan Guo, Yun Zhang, Azeem Intisar, Qamar Subhani, Muhammad Abdul Qadir, Hairong Cui. (2019) Online clean-up setup for the determination of non-fluorescent acidic pharmaceutical drugs in complex biological samples. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1126-1127 (121708). [PMID:31437773] [10.1016/j.jchromb.2019.06.035]
11. Ji Ma, Hongli Yin, Maoru Li, Yang Deng, Owais Ahmad, Guohong Qin, Qiangqiang He, Jiajing Li, Kai Gao, Junyi Zhu, Bing Wang, Susu Wu, Tao Wang, Jing Shang. (2019) A Comprehensive Study of High Cholesterol Diet-Induced Larval Zebrafish Model: A Short-Time In Vivo Screening Method for Non-Alcoholic Fatty Liver Disease Drugs. International Journal of Biological Sciences, 15 (5): ( 973–983). [PMID:31182918] [10.7150/ijbs.30013]
12. Shen Chang-shuai, Zhou Cai-rong. (2016) Investigation of the thermal decomposition kinetics of bezafibrate. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 126 (2): (959-967). [PMID:] [10.1007/s10973-016-5565-9]

References

1. Huimin Zhou, Zhiwei Qiu, Jin Zeng, Ruobin Dai, Zhiwei Wang. (2023) Ultra-permeable polyamide nanofiltration membrane modified by hydrophilic-hydrophobic alternated lignocellulosic nanofibrils for efficient water reuse. JOURNAL OF MEMBRANE SCIENCE, 688 (15): (122125). [PMID:10677542] [10.1016/j.memsci.2023.122125]
2. Xuecong Qian, Shilong Wang, Haijun Cheng, Ziye Jia, Da Wang, Yandong Xie, Jinhao Duan, Yu Tian, Jun Ma. (2023) Mn(II) oxidation by the UV/chlorine system under near-neutral pH conditions: The important role of ClO· and ClO2. WATER RESEARCH, 246 (28): (120673). [PMID:37844341] [10.1016/j.watres.2023.120673]
3. Mingming Qi, Hui Zhong, Zhaoyan Cheng, Shujie Chen, Han Xiao, Jing Shang, Li Chen, Jianbo Sun. (2023) Discovery of NAFLD-Improving Agents by Promoting the Degradation of Keap1. JOURNAL OF MEDICINAL CHEMISTRY, [PMID:37386884] [10.1021/acs.jmedchem.3c00822]
4. Tianhua He, Nikita Lykov, Xu Luo, Huiling Wang, Zhanxiang Du, Ziyi Chen, Shitian Chen, Lin Zhu, Ye Zhao, Chimeng Tzeng. (2023) Protective Effects of Lactobacillus gasseri against High-Cholesterol Diet-Induced Fatty Liver and Regulation of Host Gene Expression Profiles. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (3): (2053). [PMID:36768377] [10.3390/ijms24032053]
5. Ji Ma, Yang Deng, Tingting Yang, Maoru Li, Jing Shang. (2023) Esculetin Alleviates Nonalcoholic Fatty Liver Disease on High-Cholesterol-Diet-Induced Larval Zebrafish and FFA-Induced BRL-3A Hepatocyte. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (2): (1593). [PMID:36675107] [10.3390/ijms24021593]
6. Hui Su, Xudan Dou, Dandan Xu, Li Feng, Yongze Liu, Ziwen Du, Liqiu Zhang. (2022) Fe0-loaded superfine powdered activated carbon prepared by ball milling for synergistic adsorption and persulfate activation to remove aqueous carbamazepine. CHEMOSPHERE, 293 (133665). [PMID:35051510] [10.1016/j.chemosphere.2022.133665]
7. Xiangyu Chen, Juanjuan Yao, Hongsen Dong, Mingjian Hong, Naiyun Gao, Zhi Zhang, Wenchao Jiang. (2021) Enhanced bezafibrate degradation and power generation via the simultaneous PMS activation in visible light photocatalytic fuel cell. WATER RESEARCH, 207 (117800). [PMID:34741902] [10.1016/j.watres.2021.117800]
8. Yang Deng, Ji Ma, Xin Weng, Yuqin Wang, Maoru Li, Tingting Yang, Zhiyang Dou, Zhiqi Yin, Jing Shang. (2021) Kaempferol-3-O-Glucuronide Ameliorates Non-Alcoholic Steatohepatitis in High-Cholesterol-Diet-Induced Larval Zebrafish and HepG2 Cell Models via Regulating Oxidation Stress. Life-Basel, 11 (5): (445). [PMID:34069176] [10.3390/life11050445]
9. Yang Guo, Erzhuo Zhao, Jun Wang, Xiaoyuan Zhang, Haiou Huang, Gang Yu, Yujue Wang. (2020) Comparison of emerging contaminant abatement by conventional ozonation, catalytic ozonation, O3/H2O2 and electro-peroxone processes. JOURNAL OF HAZARDOUS MATERIALS, 389 (121829). [PMID:31836369] [10.1016/j.jhazmat.2019.121829]
10. Nadeem Muhammad, Dandan Guo, Yun Zhang, Azeem Intisar, Qamar Subhani, Muhammad Abdul Qadir, Hairong Cui. (2019) Online clean-up setup for the determination of non-fluorescent acidic pharmaceutical drugs in complex biological samples. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1126-1127 (121708). [PMID:31437773] [10.1016/j.jchromb.2019.06.035]
11. Ji Ma, Hongli Yin, Maoru Li, Yang Deng, Owais Ahmad, Guohong Qin, Qiangqiang He, Jiajing Li, Kai Gao, Junyi Zhu, Bing Wang, Susu Wu, Tao Wang, Jing Shang. (2019) A Comprehensive Study of High Cholesterol Diet-Induced Larval Zebrafish Model: A Short-Time In Vivo Screening Method for Non-Alcoholic Fatty Liver Disease Drugs. International Journal of Biological Sciences, 15 (5): ( 973–983). [PMID:31182918] [10.7150/ijbs.30013]
12. Shen Chang-shuai, Zhou Cai-rong. (2016) Investigation of the thermal decomposition kinetics of bezafibrate. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 126 (2): (959-967). [PMID:] [10.1007/s10973-016-5565-9]

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Bezafibrate - ≥98%, high purity , Peroxisome proliferator-activated receptor agonist, CAS No.41859-67-0, Peroxisome proliferator-activated receptor agonist

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