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BGP 15 - 10mM in DMSO, high purity , CAS No.66611-37-8

Item Number

B425352

Grouped product items
SKU	Size	Availability	Price	Qty
B425352-1ml	1ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$214.90

PARP inhibitor; cytoprotectant

Basic Description

Synonyms	BGP-15 \| 66611-37-8 \| N-(2-Hydroxy-3-(piperidin-1-yl)propoxy)nicotinimidamide dihydrochloride \| 3-Pyridinecarboximidamide, N-(2-hydroxy-3-(1-piperidinyl)propoxy)-, hydrochloride (1:2) \| RLN2GTG4YS \| N'-(2-hydroxy-3-piperidin-1-ylpropoxy)pyridine-3-carboximidamide;d
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	PARP inhibitor (IC50= 120 μM). Displays cytoprotective effects in various disease models: decreases ROS levels, lipid peroxidation and single-strand DNA breaks in isolated reperfused rat hearts; improves mitochondrial function and protects against neurona
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads

SARS-CoV-2 (38078 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

IUPAC Name	N'-(2-hydroxy-3-piperidin-1-ylpropoxy)pyridine-3-carboximidamide;dihydrochloride
INCHI	InChI=1S/C14H22N4O2.2ClH/c15-14(12-5-4-6-16-9-12)17-20-11-13(19)10-18-7-2-1-3-8-18;;/h4-6,9,13,19H,1-3,7-8,10-11H2,(H2,15,17);2*1H
InChi Key	ISGGVCWFTPTHIX-UHFFFAOYSA-N
Canonical SMILES	C1CCN(CC1)CC(CON=C(C2=CN=CC=C2)N)O.Cl.Cl
Isomeric SMILES	C1CCN(CC1)CC(CO/N=C(/C2=CN=CC=C2)\N)O.Cl.Cl
Alternate CAS	459809-32-6
PubChem CID	9884807
Molecular Weight	351.27

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Sensitivity	Moisture sensitive.

Pictogram(s)	GHS06
Signal	Danger
Hazard Statements	H301:Toxic if swallowed
Precautionary Statements	P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately.

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