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BI 6015 - ≥98%(HPLC), high purity , CAS No.93987-29-2, Antagonist of Hepatocyte nuclear factor-4-α
Hepatocyte nuclear factor 4α (HNF4α) antagonist
Basic Description Synonyms BI6015 | bi-6015 | GTPL6695 | 2-methyl-1-(2-methyl-5-nitrobenzenesulfonyl)-1H-1,3-benzodiazole | HY-108469 | EX-A7599 | 2-methyl-1-[(2-methyl-5-nitrophenyl)sulfonyl]-1H-benzimidazole | Q27075218 | Z276545864 | 2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbe Specifications & Purity Moligand™, ≥98%(HPLC) Biochemical and Physiological Mechanisms Hepatocyte nuclear factor 4α(HNF4α) antagonist. Represses expression of known HNF4αtarget genes. Decreases HNF4αDNA binding. Exhibits cytotoxic activity in a range of tumor cell lines, including human hepatocellular carcinoma. Storage Temp Protected from light,Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type ANTAGONIST Mechanism of action Antagonist of Hepatocyte nuclear factor-4-α
Associated Targets(Human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name 2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbenzimidazole INCHI InChI=1S/C15H13N3O4S/c1-10-7-8-12(18(19)20)9-15(10)23(21,22)17-11(2)16-13-5-3-4-6-14(13)17/h3-9H,1-2H3 InChi Key ILVCPQPMRPHZSG-UHFFFAOYSA-N Canonical SMILES CC1=C(C=C(C=C1)[N+](=O)[O-])S(=O)(=O)N2C(=NC3=CC=CC=C32)C Isomeric SMILES CC1=C(C=C(C=C1)[N+](=O)[O-])S(=O)(=O)N2C(=NC3=CC=CC=C32)C PubChem CID 3269393 Molecular Weight 331.35
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 6.63, Max Conc. mM: 20 Sensitivity light sensitive
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K2229496