Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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B129316-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $28.90 | |
B129316-5g | 5g | In stock | $86.90 | |
B129316-25g | 25g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $389.90 | |
B129316-100g | 100g | In stock | $1,400.90 | |
B129316-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $6,302.90 |
Synonyms | Bifonazol | Bifonazolum | DL-338 | 1-[phenyl-(4-phenylphenyl)methyl]imidazole | MRF-0000274 | NCGC00018254-05 | NCGC00089815-04 | Bay H-4502 | HMS2093B09 | HMS2232J24 | Mycospor (TN) | 1-[biphenyl-4-yl(phenyl)methyl]imidazole | EINECS 262-336-6 | NSC75895 |
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Specifications & Purity | ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Bifonazole is an imidazole antifungal agent and calmodulin antagonist. It causes a reduction in glycolysis and ATP levels in B16 melanoma cells. Bifonazole is an inhibitor of C14orf1. |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Action Type | INHIBITOR |
Mechanism of action | HMG-CoA reductase inhibitor |
Product Description | Bifonazole is an antifungal agent and a prostatic aromatase activity inhibitor with IC50 of 1.6 μM. |
ALogP | 4.8 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 1-[phenyl-(4-phenylphenyl)methyl]imidazole |
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INCHI | InChI=1S/C22H18N2/c1-3-7-18(8-4-1)19-11-13-21(14-12-19)22(24-16-15-23-17-24)20-9-5-2-6-10-20/h1-17,22H |
InChi Key | OCAPBUJLXMYKEJ-UHFFFAOYSA-N |
Canonical SMILES | C1=CC=C(C=C1)C2=CC=C(C=C2)C(C3=CC=CC=C3)N4C=CN=C4 |
Isomeric SMILES | C1=CC=C(C=C1)C2=CC=C(C=C2)C(C3=CC=CC=C3)N4C=CN=C4 |
WGK Germany | 3 |
RTECS | NI3517000 |
PubChem CID | 2378 |
Molecular Weight | 310.39 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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J2211844 | Certificate of Analysis | Jul 17, 2024 | B129316 |
J2211846 | Certificate of Analysis | Jul 17, 2024 | B129316 |
J2211852 | Certificate of Analysis | Jul 17, 2024 | B129316 |
J2211853 | Certificate of Analysis | Jul 17, 2024 | B129316 |
E1520118 | Certificate of Analysis | Dec 07, 2022 | B129316 |
D2422089 | Certificate of Analysis | Jul 23, 2022 | B129316 |
A2210080 | Certificate of Analysis | Jan 12, 2022 | B129316 |
C2223071 | Certificate of Analysis | Jan 12, 2022 | B129316 |
Solubility | Soluble in DMSO (62 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), ethanol (20 mg/ml at 25 °C), alcohols, and DMF. |
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Melt Point(°C) | 149 °C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H302:Harmful if swallowed |
Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
WGK Germany | 3 |
RTECS | NI3517000 |
Merck Index | 1213 |
1. Susu Lin, Bingbing Ma, Qilin Gao, Jian Yang, Gang Lai, Runhao Lin, Bingxian Yang, Bing-Nan Han, Lian-Hua Xu. (2022) The 16α-Hydroxylation of Progesterone by Cytochrome P450 107X1 from Streptomyces avermitilis. CHEMISTRY & BIODIVERSITY, 19 (5): (e202200177). [PMID:35426465] |
1. Susu Lin, Bingbing Ma, Qilin Gao, Jian Yang, Gang Lai, Runhao Lin, Bingxian Yang, Bing-Nan Han, Lian-Hua Xu. (2022) The 16α-Hydroxylation of Progesterone by Cytochrome P450 107X1 from Streptomyces avermitilis. CHEMISTRY & BIODIVERSITY, 19 (5): (e202200177). [PMID:35426465] |