Click Here for 5% Off Your First Aladdin Purchase!

Biotin - meets USP testing specifications, high purity , CAS No.58-85-5

  • PharmPure™
  • USP
Item Number
B476742
Grouped product items
SKUSizeAvailabilityPrice Qty
B476742-500mg
500mg
In stock
$265.90
B476742-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$2,226.90
B476742-25g
25g
In stock
$7,295.90

Basic Description

Synonymsbiotin|d-biotin|58-85-5|vitamin H|Vitamin B7|Bioepiderm|coenzyme R|Bios II|Factor S|D(+)-Biotin|Biodermatin|D-(+)-Biotin|(+)-Biotin|Biotine|Biotinum|Injacom H|Biotina|Meribin|Factor S (vitamin)|Lutavit H2|Ritatin|CCRIS 3932|HSDB 346|3H-Biotin|MFCD00005541
Specifications & PurityPharmPure™, USP
Biochemical and Physiological MechanismsEssential vitamin that is important for amino acid and energy metabolism, and fatty acid synthesis. It is a prosthetic group in four mammalian carboxylase families and facilitates the binding and transfer of carbon dioxide.
Storage TempStore at 2-8°C
Shipped InWet ice
GradePharmPure™, USP

Associated Targets

CUX1 Tbio Homeobox protein cut-like 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CNR1 Tclin Cannabinoid receptor 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DRD1 Tclin D(1A) dopamine receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DRD2 Tclin D(2) dopamine receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ESR1 Tclin Estrogen receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR3C1 Tclin Glucocorticoid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AVPR1A Tclin Vasopressin V1a receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HRH1 Tclin Histamine H1 receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC6A2 Tclin Sodium-dependent noradrenaline transporter 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC6A3 Tclin Sodium-dependent dopamine transporter 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC6A4 Tclin Sodium-dependent serotonin transporter 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PDE4D Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PDE3A Tclin cGMP-inhibited 3',5'-cyclic phosphodiesterase A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGS2 Tclin Prostaglandin G/H synthase 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CACNA1C Tclin Voltage-dependent L-type calcium channel subunit alpha-1C 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DRD3 Tclin D(3) dopamine receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRM3 Tclin Muscarinic acetylcholine receptor M3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA2B Tclin Alpha-2B adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRM2 Tclin Muscarinic acetylcholine receptor M2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA2C Tclin Alpha-2C adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR2A Tclin 5-hydroxytryptamine receptor 2A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADORA2A Tclin Adenosine receptor A2a 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABL1 Tclin Tyrosine-protein kinase ABL1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRM1 Tclin Muscarinic acetylcholine receptor M1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA2A Tclin Alpha-2A adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRB1 Tclin Beta-1 adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA1A Tclin Alpha-1A adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AR Tclin Androgen receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR2C Tclin 5-hydroxytryptamine receptor 2C 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADORA1 Tclin Adenosine receptor A1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR1A Tclin 5-hydroxytryptamine receptor 1A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADORA3 Tchem Adenosine receptor A3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR3A Tclin 5-hydroxytryptamine receptor 3A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR2B Tclin 5-hydroxytryptamine receptor 2B 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TBXA2R Tclin Thromboxane A2 receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

OPRD1 Tclin Delta-type opioid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

OPRK1 Tclin Kappa-type opioid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

OPRM1 Tclin Mu-type opioid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KDM4A Tchem Lysine-specific demethylase 4A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MLNR Tchem Motilin receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid
INCHI InChI=1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1
InChi Key YBJHBAHKTGYVGT-ZKWXMUAHSA-N
Canonical SMILES [H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2
Isomeric SMILES C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)O)NC(=O)N2
WGK Germany 1
RTECS XJ9088200
PubChem CID 171548
Molecular Weight 244.31
Beilstein 86838

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot NumberCertificate TypeDateItem
F2310767Certificate of AnalysisJun 21, 2023 B476742
F2310769Certificate of AnalysisJun 14, 2023 B476742
F2310768Certificate of AnalysisJun 13, 2023 B476742

Chemical and Physical Properties

Specific Rotation[α]90.5 ° (C=2, 0.1mol/L NaOH)
Melt Point(°C)232-233°C

Safety and Hazards(GHS)

WGK Germany 1
RTECS XJ9088200

Related Documents

References

1. Tong L.  (2013)  Structure and function of biotin-dependent carboxylases..  Cell Mol Life Sci,  70  (5): (863-91).  [PMID:22869039]
2. Lietzan AD, St Maurice M.  (2014)  Functionally diverse biotin-dependent enzymes with oxaloacetate decarboxylase activity..  Arch Biochem Biophys,  544  (3): (75-86).  [PMID:24184447]
3. L P Thuy,L Sweetman,W L Nyhan.  (1991-10-31)  A new immunochemical assay for biotin..  Clinica chimica acta; international journal of clinical chemistry,  202  ((3)): (191-197).  [PMID:1814646]
4. S Schenker,Z Q Hu,R F Johnson,Y Yang,T Frosto,B D Elliott,G I Henderson,D M Mock.  (1993-06-01)  Human placental biotin transport: normal characteristics and effect of ethanol..  Alcoholism, clinical and experimental research,  17  ((3)): (566-575).  [PMID:8333586]
5. L P Thuy,J Belmont,W L Nyhan.  (1999-04-24)  Prenatal diagnosis and treatment of holocarboxylase synthetase deficiency..  Prenatal diagnosis,  19  ((2)): (108-112).  [PMID:10215065]
6. E Livaniou,J O Nyalala,M Anagnostouli,C Papageorgiou,G P Evangelatos,D S Ithakissios.  (2000-03-04)  Determination of biotin levels in cerebrospinal fluid samples..  Journal of pharmaceutical and biomedical analysis,  21  ((4)): (875-879).  [PMID:10701954]
7. D M Mock,J O Nyalala,R M Raguseo.  (2001-08-02)  A direct streptavidin-binding assay does not accurately quantitate biotin in human urine..  The Journal of nutrition,  131  ((8)): (2208-2214).  [PMID:11481419]
8. Roy A Gravel,Monica A Narang.  (2005-07-05)  Molecular genetics of biotin metabolism: old vitamin, new science..  The Journal of nutritional biochemistry,  16  ((7)): (428-431).  [PMID:15992684]
9. Jon-Paul Bingham,Shumin Bian,Zhi-Yong Tan,Zoltan Takacs,Edward Moczydlowski.  (2006-05-18)  Synthesis of a biotin derivative of iberiotoxin: binding interactions with streptavidin and the BK Ca2+-activated K+ channel expressed in a human cell line..  Bioconjugate chemistry,  17  ((3)): (689-699).  [PMID:16704206]
10. D Wang,C R Stockard,L Harkins,P Lott,C Salih,K Yuan,D Buchsbaum,A Hashim,M Zayzafoon,R W Hardy,O Hameed,W Grizzle,G P Siegal.  (2008-10-11)  Immunohistochemistry in the evaluation of neovascularization in tumor xenografts..  Biotechnic & histochemistry : official publication of the Biological Stain Commission,  83  ((3-4)): (179-189).  [PMID:18846440]
11. Chawin Ounkomol,Hongtao Xie,Paul A Dayton,Volkmar Heinrich.  (2009-02-03)  Versatile horizontal force probe for mechanical tests on pipette-held cells, particles, and membrane capsules..  Biophysical journal,  96  ((3)): (1218-1231).  [PMID:19186156]
12. Arun Sreekumar,Laila M Poisson,Thekkelnaycke M Rajendiran,Amjad P Khan,Qi Cao,Jindan Yu,Bharathi Laxman,Rohit Mehra,Robert J Lonigro,Yong Li,Mukesh K Nyati,Aarif Ahsan,Shanker Kalyana-Sundaram,Bo Han,Xuhong Cao,Jaeman Byun,Gilbert S Omenn,Debashis Ghosh,Subramaniam Pennathur,Danny C Alexander,Alvin Berger,Jeffrey R Shuster,John T Wei,Sooryanarayana Varambally,Christopher Beecher,Arul M Chinnaiyan.  (2009-02-13)  Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression..  Nature,  457  ((7231)): (910-914).  [PMID:19212411]
13. T I El-Hajj,P E Karam,M A Mikati.  (2009-03-19)  Biotin-responsive basal ganglia disease: case report and review of the literature..  Neuropediatrics,  39  ((5)): (268-271).  [PMID:19294600]
14. Janos Zempleni,Subhashinee S K Wijeratne,Yousef I Hassan.  (2009-03-26)  Biotin..  BioFactors (Oxford, England),  35  ((1)): (36-46).  [PMID:19319844]
15. Juha A E Määttä,Satu H Helppolainen,Vesa P Hytönen,Mark S Johnson,Markku S Kulomaa,Tomi T Airenne,Henri R Nordlund.  (2009-10-01)  Structural and functional characteristics of xenavidin, the first frog avidin from Xenopus tropicalis..  BMC structural biology,  (63-63).  [PMID:19788720]
16. Hanna P Lesch,Minna U Kaikkonen,Jere T Pikkarainen,Seppo Ylä-Herttuala.  (2010-03-18)  Avidin-biotin technology in targeted therapy..  Expert opinion on drug delivery,  ((5)): (551-564).  [PMID:20233034]
17. Nigel Greene,Lilia Fisk,Russell T Naven,Reine R Note,Mukesh L Patel,Dennis J Pelletier.  (2010-06-18)  Developing structure-activity relationships for the prediction of hepatotoxicity..  Chemical research in toxicology,  23  ((7)): (1215-1222).  [PMID:20553011]
18. Israel S Fernández,Akio Yamashita,Ernesto Arias-Palomo,Yumi Bamba,Ruben A Bartolomé,M Angeles Canales,Joaquín Teixidó,Shigeo Ohno,Oscar Llorca.  (2010-09-08)  Characterization of SMG-9, an essential component of the nonsense-mediated mRNA decay SMG1C complex..  Nucleic acids research,  39  ((1)): (347-358).  [PMID:20817927]
19. Sean Ekins,Antony J Williams,Jinghai J Xu.  (2010-09-17)  A predictive ligand-based Bayesian model for human drug-induced liver injury..  Drug metabolism and disposition: the biological fate of chemicals,  38  ((12)): (2302-2308).  [PMID:20843939]
20. Shuichi Nakanishi,Hiroyuki Tanaka,Kazuhito Hioki,Kohei Yamada,Munetaka Kunishima.  (2010-10-16)  Labeling study of avidin by modular method for affinity labeling (MoAL)..  Bioorganic & medicinal chemistry letters,  20  ((23)): (7050-7053).  [PMID:20947347]
21. Yuxi Feng,Yumei Wang,Li Li,Liang Wu,Sigrid Hoffmann,Norbert Gretz,Hans-Peter Hammes.  (2011-03-08)  Gene expression profiling of vasoregression in the retina--involvement of microglial cells..  PloS one,  ((2)): (e16865-e16865).  [PMID:21379381]
22. John E Cronan,Steven Lin.  (2011-03-26)  Synthesis of the α,ω-dicarboxylic acid precursor of biotin by the canonical fatty acid biosynthetic pathway..  Current opinion in chemical biology,  15  ((3)): (407-413).  [PMID:21435937]
23. Steven Lin,John E Cronan.  (2011-03-26)  Closing in on complete pathways of biotin biosynthesis..  Molecular bioSystems,  ((6)): (1811-1821).  [PMID:21437340]
24. B Chen,C Wang,Y M Wang,J X Liu.  (2011-06-28)  Effect of biotin on milk performance of dairy cattle: a meta-analysis..  Journal of dairy science,  94  ((7)): (3537-3546).  [PMID:21700041]
25. Bo Zhong,Rati Lama,Kerri M Smith,Yan Xu,Bin Su.  (2011-08-03)  Design and synthesis of a biotinylated probe of COX-2 inhibitor nimesulide analog JCC76..  Bioorganic & medicinal chemistry letters,  21  ((18)): (5324-5327).  [PMID:21807508]
26. Janos Zempleni,Daniel Camara Teixeira,Toshinobu Kuroishi,Elizabeth L Cordonier,Scott Baier.  (2011-08-30)  Biotin requirements for DNA damage prevention..  Mutation research,  733  ((1-2)): (58-60).  [PMID:21871906]
27. Abdussalam Adina-Zada,Tonya N Zeczycki,Martin St Maurice,Sarawut Jitrapakdee,W Wallace Cleland,Paul V Attwood.  (2012-05-24)  Allosteric regulation of the biotin-dependent enzyme pyruvate carboxylase by acetyl-CoA..  Biochemical Society transactions,  40  ((3)): (567-572).  [PMID:22616868]
28. Grover L Waldrop,Hazel M Holden,Martin St Maurice.  (2012-09-13)  The enzymes of biotin dependent CO₂ metabolism: what structures reveal about their reaction mechanisms..  Protein science : a publication of the Protein Society,  21  ((11)): (1597-1619).  [PMID:22969052]
29. Jun-ichi Maruyama,Shohei Yamaoka,Ichiro Matsuo,Nobuhiro Tsutsumi,Katsuhiko Kitamoto.  (2012-10-18)  A newly discovered function of peroxisomes: involvement in biotin biosynthesis..  Plant signaling & behavior,  ((12)): (1589-1593).  [PMID:23073000]
30. José Antonio Nieto Rodríguez.  (2013-03-27)  [New approaches in the treatment of deep vein thrombosis]..  Medicina clinica,  139 Suppl 2  (19-23).  [PMID:23498068]
31. Timothy Sanchez,Zvonimir Dogic.  (2013-03-19)  Engineering oscillating microtubule bundles..  Methods in enzymology,  524  (205-224).  [PMID:23498742]
32. K Dzitko,B Dziadek,J Gatkowska,H Długońska.  (2013-03-19)  Toxoplasma gondii binds sheep prolactin..  Experimental parasitology,  134  ((2)): (216-219).  [PMID:23499881]
33. P Prandoni,F Dalla Valle,C Piovella,D Tormene,R Pesavento.  (2013-03-22)  New anticoagulants for the treatment of venous thromboembolism..  Minerva medica,  104  ((2)): (131-139).  [PMID:23514989]
34. Ria M Cooke,Rajendra Mistry,R A John Challiss,Volko A Straub.  (2013-03-29)  Nitric oxide synthesis and cGMP production is important for neurite growth and synapse remodeling after axotomy..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  33  ((13)): (5626-5637).  [PMID:23536077]
35. Ling-Xiao Deng,Ping Deng,Yiwen Ruan,Zao Cheng Xu,Nai-Kui Liu,Xuejun Wen,George M Smith,Xiao-Ming Xu.  (2013-03-29)  A novel growth-promoting pathway formed by GDNF-overexpressing Schwann cells promotes propriospinal axonal regeneration, synapse formation, and partial recovery of function after spinal cord injury..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  33  ((13)): (5655-5667).  [PMID:23536080]
36. Wei Xu,Yiu Chung Tse,Frederick A Dobie,Michel Baudry,Ann Marie Craig,Tak Pan Wong,Yu Tian Wang.  (2013-03-29)  Simultaneous monitoring of presynaptic transmitter release and postsynaptic receptor trafficking reveals an enhancement of presynaptic activity in metabotropic glutamate receptor-mediated long-term depression..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  33  ((13)): (5867-5877).  [PMID:23536098]
37. Lezanne Ooi,Sylvain Gigout,Louisa Pettinger,Nikita Gamper.  (2013-04-05)  Triple cysteine module within M-type K+ channels mediates reciprocal channel modulation by nitric oxide and reactive oxygen species..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  33  ((14)): (6041-6046).  [PMID:23554485]
38. Tuan V Bui,Turgay Akay,Osama Loubani,Thomas S Hnasko,Thomas M Jessell,Robert M Brownstone.  (2013-04-16)  Circuits for grasping: spinal dI3 interneurons mediate cutaneous control of motor behavior..  Neuron,  78  ((1)): (191-204).  [PMID:23583114]
39. Belén Pérez-Dueñas,Mercedes Serrano,Mónica Rebollo,Jordi Muchart,Eva Gargallo,Celine Dupuits,Rafael Artuch.  (2013-04-17)  Reversible lactic acidosis in a newborn with thiamine transporter-2 deficiency..  Pediatrics,  131  ((5)): (e1670-e1675).  [PMID:23589815]
40. James A Corson,Alev Erisir.  (2013-05-04)  Monosynaptic convergence of chorda tympani and glossopharyngeal afferents onto ascending relay neurons in the nucleus of the solitary tract: a high-resolution confocal and correlative electron microscopy approach..  The Journal of comparative neurology,  521  ((13)): (2907-2926).  [PMID:23640852]
41. Georgia Thodi,Kleopatra H Schulpis,Elina Molou,Vassiliki Georgiou,Yannis L Loukas,Yannis Dotsikas,Konstantinos Papadopoulos,Sofia Biti.  (2013-05-07)  High incidence of partial biotinidase deficiency cases in newborns of Greek origin..  Gene,  524  ((2)): (361-362).  [PMID:23644139]
42. Claude Robert,Laurence Bourgeais,Charles-Daniel Arreto,Miguel Condes-Lara,Rodrigo Noseda,Thérèse Jay,Luis Villanueva.  (2013-05-17)  Paraventricular hypothalamic regulation of trigeminovascular mechanisms involved in headaches..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  33  ((20)): (8827-8840).  [PMID:23678125]
43. Tazu Aoki,Masae Kinoshita,Ryo Aoki,Masakazu Agetsuma,Hidenori Aizawa,Masako Yamazaki,Mikako Takahoko,Ryunosuke Amo,Akiko Arata,Shin-ichi Higashijima,Takashi Tsuboi,Hitoshi Okamoto.  (2013-05-21)  Imaging of neural ensemble for the retrieval of a learned behavioral program..  Neuron,  78  ((5)): (881-894).  [PMID:23684786]
44. Elenia Cinelli,Brita Robertson,Donatella Mutolo,Sten Grillner,Tito Pantaleo,Fulvia Bongianni.  (2013-05-24)  Neuronal mechanisms of respiratory pattern generation are evolutionary conserved..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  33  ((21)): (9104-9112).  [PMID:23699521]
45. Sari Pihlasalo,Jenny Granberg,Pekka Hänninen,Jouko Peltonen,Harri Härmä.  (2013-05-25)  Luminescence stability improvement in liposome-based homogeneous luminescence resonance energy transfer..  Analytical biochemistry,  440  ((1)): (6-8).  [PMID:23702341]
46. Ye Yao,Linjun Chen,Wei Wei,Xiaohui Deng,Liyuan Ma,Siguo Hao.  (2013-05-28)  Tumor cell-derived exosome-targeted dendritic cells stimulate stronger CD8+ CTL responses and antitumor immunities..  Biochemical and biophysical research communications,  436  ((1)): (60-65).  [PMID:23707941]
47. Isabel Márquez-Sillero,Soledad Cárdenas,Miguel Valcárcel.  (2013-06-04)  Determination of water-soluble vitamins in infant milk and dietary supplement using a liquid chromatography on-line coupled to a corona-charged aerosol detector..  Journal of chromatography. A,  1313  (253-258).  [PMID:23726354]
48. Majid Alfadhel,Makki Almuntashri,Raafat H Jadah,Fahad A Bashiri,Muhammad Talal Al Rifai,Hisham Al Shalaan,Mohammed Al Balwi,Ahmed Al Rumayan,Wafaa Eyaid,Waleed Al-Twaijri.  (2013-06-08)  Biotin-responsive basal ganglia disease should be renamed biotin-thiamine-responsive basal ganglia disease: a retrospective review of the clinical, radiological and molecular findings of 18 new cases..  Orphanet journal of rare diseases,  (83-83).  [PMID:23742248]
49. Pascal Loyer,Wahib Bedhouche,Zhi Wei Huang,Sandrine Cammas-Marion.  (2013-06-12)  Degradable and biocompatible nanoparticles decorated with cyclic RGD peptide for efficient drug delivery to hepatoma cells in vitro..  International journal of pharmaceutics,  454  ((2)): (727-737).  [PMID:23747504]
50. Kai Zhang,Ke Wang,Minhao Xie,Lan Xu,Xue Zhu,Shiyang Pan,Qun Zhang,Biao Huang.  (2013-06-19)  A new method for the detection of adenosine based on time-resolved fluorescence sensor..  Biosensors & bioelectronics,  49  (226-230).  [PMID:23770393]
51. A Abd El-Wahab,D Radko,J Kamphues.  (2013-06-19)  High dietary levels of biotin and zinc to improve health of foot pads in broilers exposed experimentally to litter with critical moisture content..  Poultry science,  92  ((7)): (1774-1782).  [PMID:23776264]
52. Marco R Celio,Alexandre Babalian,Quan Hue Ha,Simone Eichenberger,Laurence Clément,Christiane Marti,Clifford B Saper.  (2013-06-22)  Efferent connections of the parvalbumin-positive (PV1) nucleus in the lateral hypothalamus of rodents..  The Journal of comparative neurology,  521  ((14)): (3133-3153).  [PMID:23787784]
53. Konstantinos Ampatzis,Jianren Song,Jessica Ausborn,Abdeljabbar El Manira.  (2013-06-28)  Pattern of innervation and recruitment of different classes of motoneurons in adult zebrafish..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  33  ((26)): (10875-10886).  [PMID:23804107]
54. Wei Ren,Hongmei Liu,Wenxia Yang,Yunlong Fan,Lang Yang,Yucong Wang,Chenghui Liu,Zhengping Li.  (2013-06-29)  A cytometric bead assay for sensitive DNA detection based on enzyme-free signal amplification of hybridization chain reaction..  Biosensors & bioelectronics,  49  (380-386).  [PMID:23807231]
55. Friedrich Finkenwirth,Franziska Kirsch,Thomas Eitinger.  (2013-07-10)  Solitary BioY proteins mediate biotin transport into recombinant Escherichia coli..  Journal of bacteriology,  195  ((18)): (4105-4111).  [PMID:23836870]
56. Dae-Sung Lee,Jin-Seung Park,Eun Jung Lee,Hyun Jin Kim,Jeewon Lee.  (2013-07-16)  A protein nanofiber hydrogel for sensitive immunoassays..  The Analyst,  138  ((17)): (4786-4794).  [PMID:23853778]
57. Poorni R Adikaram,Dorothy Beckett.  (2013-07-31)  Protein:protein interactions in control of a transcriptional switch..  Journal of molecular biology,  425  ((22)): (4584-4594).  [PMID:23896299]
58. Christoph Hirschhäuser,Juraj Velcicky,Daniel Schlawe,Erik Hessler,André Majdalani,Jörg-Martin Neudörfl,Aram Prokop,Thomas Wieder,Hans-Günther Schmalz.  (2013-08-13)  Nucleoside analogues with a 1,3-diene-Fe(CO)3 substructure: stereoselective synthesis, configurational assignment, and apoptosis-inducing activity..  Chemistry (Weinheim an der Bergstrasse, Germany),  19  ((39)): (13017-13029).  [PMID:23934861]
59. Elena de Juan-Franco,J M Rodríguez-Frade,M Mellado,Laura M Lechuga.  (2013-08-21)  Implementation of a SPR immunosensor for the simultaneous detection of the 22K and 20K hGH isoforms in human serum samples..  Talanta,  114  (268-275).  [PMID:23953470]
60. Christopher Eginton,Dorothy Beckett.  (2013-08-30)  A large solvent isotope effect on protein association thermodynamics..  Biochemistry,  52  ((38)): (6595-6600).  [PMID:23984950]
61. J Xue,J Zempleni.  (2013-09-07)  Epigenetic synergies between biotin and folate in the regulation of pro-inflammatory cytokines and repeats..  Scandinavian journal of immunology,  78  ((5)): (419-425).  [PMID:24007195]
62. Frédéric Bretzner,Robert M Brownstone.  (2013-09-13)  Lhx3-Chx10 reticulospinal neurons in locomotor circuits..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  33  ((37)): (14681-14692).  [PMID:24027269]
63. Stuart Trenholm,Amanda J McLaughlin,David J Schwab,Gautam B Awatramani.  (2013-09-13)  Dynamic tuning of electrical and chemical synaptic transmission in a network of motion coding retinal neurons..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  33  ((37)): (14927-14938).  [PMID:24027292]
64. Christopher M Dundas,Daniel Demonte,Sheldon Park.  (2013-09-24)  Streptavidin-biotin technology: improvements and innovations in chemical and biological applications..  Applied microbiology and biotechnology,  97  ((21)): (9343-9353).  [PMID:24057405]
65. Andrew L Garfoot,Olga Zemska,Chad A Rappleye.  (2013-11-06)  Histoplasma capsulatum depends on de novo vitamin biosynthesis for intraphagosomal proliferation..  Infection and immunity,  82  ((1)): (393-404).  [PMID:24191299]
66. Yu-Chu Chang,James U Bowie.  (2013-12-25)  Measuring membrane protein stability under native conditions..  Proceedings of the National Academy of Sciences of the United States of America,  111  ((1)): (219-224).  [PMID:24367094]
67. Carolina Pereira Tavares,Javier Vernal,Ricardo Alexandre Delena,Lorenzo Lamattina,Raul Cassia,Hernán Terenzi.  (2014-03-04)  S-nitrosylation influences the structure and DNA binding activity of AtMYB30 transcription factor from Arabidopsis thaliana..  Biochimica et biophysica acta,  1844  ((4)): (810-817).  [PMID:24583075]
68. D Vukosavljevic,J L Hutter,E J Helmerhorst,Y Xiao,W Custodio,F C Zaidan,F G Oppenheim,W L Siqueira.  (2014-03-05)  Nanoscale adhesion forces between enamel pellicle proteins and hydroxyapatite..  Journal of dental research,  93  ((5)): (514-519).  [PMID:24591293]
69. Konstantina Papadia,Eleni Markoutsa,Sophia G Antimisiaris.  (2014-04-17)  A simplified method to attach antibodies on liposomes by biotin-streptavidin affinity for rapid and economical screening of targeted liposomes..  Journal of biomedical nanotechnology,  10  ((5)): (871-876).  [PMID:24734540]
70. Carmen Smarandache-Wellmann,Swantje Grätsch.  (2014-04-18)  Mechanisms of coordination in distributed neural circuits: encoding coordinating information..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  34  ((16)): (5627-5639).  [PMID:24741053]
71. Yoshikazu Ogawa,Takayoshi Kiba,Kikuo Nakano,Keiichi Fujiwara,Hitoshi Taniguchi,Atsuko Hosokawa,Toshihisa Nakashima,Shizue Kimoto,Sayoko Kajiume,Yuuko Okada,Yasunori Ichiba.  (2014-04-20)  [Prospective study of biotin treatment in patients with erythema due to gefitinib or erlotinib]..  Gan to kagaku ryoho. Cancer & chemotherapy,  41  ((4)): (517-522).  [PMID:24743373]
72. Jacob G Vineberg,Edison S Zuniga,Anushree Kamath,Ying-Jen Chen,Joshua D Seitz,Iwao Ojima.  (2014-06-06)  Design, synthesis, and biological evaluations of tumor-targeting dual-warhead conjugates for a taxoid-camptothecin combination chemotherapy..  Journal of medicinal chemistry,  57  ((13)): (5777-5791).  [PMID:24901491]
73. Naruo Nikoh,Takahiro Hosokawa,Minoru Moriyama,Kenshiro Oshima,Masahira Hattori,Takema Fukatsu.  (2014-07-02)  Evolutionary origin of insect-Wolbachia nutritional mutualism..  Proceedings of the National Academy of Sciences of the United States of America,  111  ((28)): (10257-10262).  [PMID:24982177]
74. R Pellicano,D G Ribaldone,G M Saracco,N Leone,C De Angelis,A Arrigoni,E Morello,N Sapone,F Cisarò,M Astegiano.  (2014-11-12)  Benefit of supplements in functional dyspepsia after treatment of Helicobacter pylori..  Minerva gastroenterologica e dietologica,  60  ((4)): (263-268).  [PMID:25384804]
75. Kazuki Ohno,Kosaku Okuda,Takashi Uehara.  (2014-12-03)  Endogenous S-sulfhydration of PTEN helps protect against modification by nitric oxide..  Biochemical and biophysical research communications,  456  ((1)): (245-249).  [PMID:25446078]
76. Haifa Chtourou,Ines Dahmen,Ahlem Jebali,Fatma Karray,Ilem Hassairi,Slim Abdelkafi,Habib Ayadi,Sami Sayadi,Abdelhafidh Dhouib.  (2015-02-27)  Characterization of Amphora sp., a newly isolated diatom wild strain, potentially usable for biodiesel production..  Bioprocess and biosystems engineering,  38  ((7)): (1381-1392).  [PMID:25716001]
77. Rebecca Mardach,Janos Zempleni,Barry Wolf,Martin J Cannon,Michael L Jennings,Sally Cress,Jane Boylan,Susan Roth,Stephen Cederbaum,Donald M Mock.  (2002-06-19)  Biotin dependency due to a defect in biotin transport..  The Journal of clinical investigation,  109  ((12)): (1617-1623).  [PMID:12070309]
78. Alyse M DeHaan,Natalie M Wolters,Evan T Keller,Kathleen M Woods Ignatoski.  (2009-01-15)  EGFR ligand switch in late stage prostate cancer contributes to changes in cell signaling and bone remodeling..  The Prostate,  69  ((5)): (528-537).  [PMID:19143022]
79. Adam D Lietzan,Martin St Maurice.  (2013-05-24)  A substrate-induced biotin binding pocket in the carboxyltransferase domain of pyruvate carboxylase..  The Journal of biological chemistry,  288  ((27)): (19915-19925).  [PMID:23698000]
80. Zhichao Liu,Qiang Shi,Don Ding,Reagan Kelly,Hong Fang,Weida Tong.  (2011-12-24)  Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps)..  PLoS computational biology,  ((12)): (e1002310-e1002310).  [PMID:22194678]
81. Christina M Van Itallie,Angel Aponte,Amber Jean Tietgens,Marjan Gucek,Karin Fredriksson,James Melvin Anderson.  (2013-04-05)  The N and C termini of ZO-1 are surrounded by distinct proteins and functional protein networks..  The Journal of biological chemistry,  288  ((19)): (13775-13788).  [PMID:23553632]

Solution Calculators