Grouped product items

SKU

Size

Availability

Price

Qty

B101527-100ml

100ml

Available within 8-12 weeks(?)

$26.90

B101527-250ml

250ml

Available within 4-8 weeks(?)

$54.90

B101527-500ml

500ml

In stock

$86.90

Basic Description

Synonyms	Bis(tetrakis(hydroxymethyl)phosphonium)sulfate (salt) \| TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULFATE \| 5I8RSL9E6S \| Octakis(hydroxymethyl)phosphonium sulfate \| THPS
Specifications & Purity	75% in water
Shipped In	Normal

Associated Targets(Human)

RORC Tchem Nuclear receptor ROR-gamma (0 Activities)

Discover Target: RORC

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

VDR Tclin Vitamin D3 receptor (0 Activities)

Discover Target: VDR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AR Tclin Androgen receptor (0 Activities)

Discover Target: AR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TP53 Tchem Cellular tumor antigen p53 (0 Activities)

Discover Target: TP53

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)

Discover Target: NFE2L2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

VDR Tclin Vitamin D receptor (26531 Activities)

Discover Target: VDR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GBA1 Tclin Beta-glucocerebrosidase (14647 Activities)

Discover Target: GBA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TP53 Tchem Cellular tumor antigen p53 (48468 Activities)

Discover Target: TP53

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Lymphoblastoid cell (5959 Activities)

Discover Target:

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	tetrakis(hydroxymethyl)phosphanium;sulfate
INCHI	InChI=1S/2C4H12O4P.H2O4S/c25-1-9(2-6,3-7)4-8;1-5(2,3)4/h25-8H,1-4H2;(H2,1,2,3,4)/q2*+1;/p-2
InChi Key	YIEDHPBKGZGLIK-UHFFFAOYSA-L
Canonical SMILES	C(O)[P+](CO)(CO)CO.C(O)[P+](CO)(CO)CO.[O-]S(=O)(=O)[O-]
Isomeric SMILES	C(O)[P+](CO)(CO)CO.C(O)[P+](CO)(CO)CO.[O-]S(=O)(=O)[O-]
WGK Germany	3
RTECS	TA2570000
PubChem CID	41478
UN Number	2922
Packing Group	I
Molecular Weight	406.28
Beilstein	8521357
Reaxy-Rn	6458412

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

13 results found

Lot Number	Certificate Type	Date	Item
E2421179	Certificate of Analysis	May 13, 2024	B101527
E2421180	Certificate of Analysis	May 13, 2024	B101527
E2421183	Certificate of Analysis	May 13, 2024	B101527
E2421189	Certificate of Analysis	May 13, 2024	B101527
E2421413	Certificate of Analysis	May 13, 2024	B101527
E2421414	Certificate of Analysis	May 13, 2024	B101527
G2416055	Certificate of Analysis	May 13, 2024	B101527
L1911005	Certificate of Analysis	Sep 08, 2023	B101527
H2224011	Certificate of Analysis	Jul 26, 2022	B101527
H2224012	Certificate of Analysis	Jul 26, 2022	B101527
H2224013	Certificate of Analysis	Jul 26, 2022	B101527
H2224014	Certificate of Analysis	Jul 26, 2022	B101527
H2224015	Certificate of Analysis	Jul 26, 2022	B101527

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Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08, GHS05
Signal	Danger
Hazard Statements	H301:Toxic if swallowed H331:Toxic if inhaled H373:Causes damage to organs through prolonged or repeated exposure H302:Harmful if swallowed H318:Causes serious eye damage H317:May cause an allergic skin reaction H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects H360:May damage fertility or the unborn child H340:May cause genetic defects H361:Suspected of damaging fertility or the unborn child H301+H331:Toxic if swallowed or if inhaled
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P281:Use personal protective equipment as required. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P316:Get emergency medical help immediately. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	TA2570000
Reaxy-Rn	6458412
Class	8, 6.1

Alternative Products

Citations of This Product

1. Fengguo Tian, Jianzhi Qiao, Wentian Zheng, Yang Lei, Shengtao Jiang, Yanbiao Liu. (2023) Flow-through electrochemical organophosphorus degradation and phosphorus recovery: The essential role of chlorine radical. ENVIRONMENTAL RESEARCH, 236 (116867). [PMID:37573819]
2. Lilong Zhou, Shenghao Wang, Zhengjie Li, Xuepu Cao, Runjing Liu, Jimmy Yun. (2023) Simultaneously removal of phosphorous and COD for purification of organophosphorus wastewater by catalytic ozonation over CaO. Journal of Water Process Engineering, 51 (103397). [PMID:]
3. Erli Yang, Hong Yang, Zhenqiang Ning, Yanfeng Fang, Mengyuan Chen, Yongjun Zheng, Wenhua Xu, Guoqiu Wu, Yuanjian Zhang, Yanfei Shen. (2022) Construction of Carbon Dots with Wavelength-Tunable Electrochemiluminescence and Enhanced Efficiency. ANALYTICAL CHEMISTRY, 94 (47): (16510–16518). [PMID:36374940]
4. Jiang Ouyang, Qingyue Bu, Na Tao, Mingkai Chen, Haijun Liu, Jun Zhou, Jinggong Liu, Bo Deng, Na Kong, Xingcai Zhang, Tianfeng Chen, Yihai Cao, Wei Tao. (2022) A facile and general method for synthesis of antibiotic-free protein-based hydrogel: Wound dressing for the eradication of drug-resistant bacteria and biofilms. Bioactive Materials, 18 (446). [PMID:35415296]
5. Guofeng Ye, Siqi Huo, Cheng Wang, Qiu Shi, Lingfeng Yu, Zhitian Liu, Zhengping Fang, Hao Wang. (2021) A novel hyperbranched phosphorus-boron polymer for transparent, flame-retardant, smoke-suppressive, robust yet tough epoxy resins. COMPOSITES PART B-ENGINEERING, 227 (109395). [PMID:]

References

1. D J Ball,S R Wood,D I Vernon,J Griffiths,T M Dubbelman,S B Brown. (1998-11-20) The characterisation of three substituted zinc phthalocyanines of differing charge for use in photodynamic therapy. A comparative study of their aggregation and photosensitising ability in relation to mTHPC and polyhaematoporphyrin.. Journal of photochemistry and photobiology. B, Biology, 45 ((1)): (28-35). [PMID:9819897]
2. R L Prosst,H C Wolfsen,J Gahlen. (2003-12-04) Photodynamic therapy for esophageal diseases: a clinical update.. Endoscopy, 35 ((12)): (1059-1068). [PMID:14648421]
3. S Sánchez-Fortún,M T Llorente,A Castaño. (2005-05-17) Genotoxic effects of selected biocides on RTG-2 fish cells by means of a modified Fast Micromethod Assay.. Aquatic toxicology (Amsterdam, Netherlands), 73 ((1)): (55-64). [PMID:15892992]
4. A J Venning,B Hill,S Brindha,B J Healy,C Baldock. (2005-08-04) Investigation of the PAGAT polymer gel dosimeter using magnetic resonance imaging.. Physics in medicine and biology, 50 ((16)): (3875-3888). [PMID:16077233]
5. María Carmen Bartolomé,Sebastián Sánchez-Fortún. (2006-02-01) Effects of selected biocides used in the disinfection of cooling towers on toxicity and bioaccumulation in Artemia larvae.. Environmental toxicology and chemistry, 24 ((12)): (3137-3142). [PMID:16445096]
6. P E Antoniou,P Bousbouras,R Sandaltzopoulos,E Kaldoudi. (2008-03-28) Investigating the potential of polymer gel dosimetry for interventional radiology: first results.. Physics in medicine and biology, 53 ((8)): (N127-N136). [PMID:18364553]
7. Tobias Kiesslich,Daniel Neureiter,Beate Alinger,Gerhard L Jansky,Juergen Berlanda,Vahagn Mkrtchyan,Matthias Ocker,Kristjan Plaetzer,Frieder Berr. (2010-04-02) Uptake and phototoxicity of meso-tetrahydroxyphenyl chlorine are highly variable in human biliary tract cancer cell lines and correlate with markers of differentiation and proliferation.. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 9 ((5)): (734-743). [PMID:20358123]
8. Jian-dong Wang,Zhi-wei Quan,Jun Shen,Xue-ping Zhou,Fang-hong Luo,Sheng-yu Wang,Jiang-hua Yan,Dong Yang. (2011-05-27) [Pharmacokinetics of photosensitizer m-THPC in rat models of liver cancer via orthotropic implantation using Walker-256].. Zhonghua wai ke za zhi [Chinese journal of surgery], 49 ((4)): (341-345). [PMID:21612701]
9. Urmimala Maitra,Barun Das,Nitesh Kumar,Athinarayanan Sundaresan,C N R Rao. (2011-07-12) Ferromagnetism exhibited by nanoparticles of noble metals.. Chemphyschem : a European journal of chemical physics and physical chemistry, 12 ((12)): (2322-2327). [PMID:21744458]
10. Baris Karakullukcu,Stephen Chad Kanick,Jan Bonne Aans,Henricus Jcm Sterenborg,I Bing Tan,Arjen Amelink,Dominic J Robinson. (2011-08-24) Clinical feasibility of monitoring m-THPC mediated photodynamic therapy by means of fluorescence differential path-length spectroscopy.. Journal of biophotonics, 4 ((10)): (740-751). [PMID:21861297]
11. Cindy Chung,Kyle J Lampe,Sarah C Heilshorn. (2012-11-16) Tetrakis(hydroxymethyl) phosphonium chloride as a covalent cross-linking agent for cell encapsulation within protein-based hydrogels.. Biomacromolecules, 13 ((12)): (3912-3916). [PMID:23151175]
12. Yao Yuan,Bin Yu,Yongqian Shi,Long Mao,Jianda Xie,Haifeng Pan,Yuejun Liu,Wei Wang. (2020-01-08) Insight into Hyper-Branched Aluminum Phosphonate in Combination with Multiple Phosphorus Synergies for Fire-Safe Epoxy Resin Composites.. Polymers, 12 ((1)): [PMID:31906381]
13. . (1990-01-01) Tetrakis(hydroxymethyl) phosphonium salts.. IARC monographs on the evaluation of carcinogenic risks to humans, 48 (95-107). [PMID:2197466]
14. T H Connor,J Meyne,M S Legator. (1980-08-01) The mutagenic evaluation of tetrakis (hydroxymethyl) phosphonium sulfate using a combined testing protocol approach.. Journal of environmental pathology and toxicology, 4 ((1)): (145-158). [PMID:7003047]
15. B Latkowski,M Gryczyński,A Murlewska. (1995-01-01) [Use of sensitizers and photo laser for diagnosis and treatment of malignant tumors].. Otolaryngologia polska = The Polish otolaryngology, 49 Suppl 20 (205-208). [PMID:9454137]
16. S G Bown,A Z Rogowska. (1999-06-23) New photosensitizers for photodynamic therapy in gastroenterology.. Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 13 ((5)): (389-392). [PMID:10377468]
17. . (1999-09-07) Tetrakis(hydroxymethyl)phosphonium salts.. IARC monographs on the evaluation of carcinogenic risks to humans, 71 Pt 3 (1529-1532). [PMID:10476439]
18. Christian Bayreder,Dietmar Georg,Ewald Moser,Andreas Berg. (2006-08-11) Basic investigations on the performance of a normoxic polymer gel with tetrakis-hydroxy-methyl-phosphonium chloride as an oxygen scavenger: reproducibility, accuracy, stability, and dose rate dependence.. Medical physics, 33 ((7)): (2506-2518). [PMID:16898454]
19. Fengguo Tian, Jianzhi Qiao, Wentian Zheng, Yang Lei, Shengtao Jiang, Yanbiao Liu. (2023) Flow-through electrochemical organophosphorus degradation and phosphorus recovery: The essential role of chlorine radical. ENVIRONMENTAL RESEARCH, 236 (116867). [PMID:37573819]
20. Lilong Zhou, Shenghao Wang, Zhengjie Li, Xuepu Cao, Runjing Liu, Jimmy Yun. (2023) Simultaneously removal of phosphorous and COD for purification of organophosphorus wastewater by catalytic ozonation over CaO. Journal of Water Process Engineering, 51 (103397). [PMID:]
21. Erli Yang, Hong Yang, Zhenqiang Ning, Yanfeng Fang, Mengyuan Chen, Yongjun Zheng, Wenhua Xu, Guoqiu Wu, Yuanjian Zhang, Yanfei Shen. (2022) Construction of Carbon Dots with Wavelength-Tunable Electrochemiluminescence and Enhanced Efficiency. ANALYTICAL CHEMISTRY, 94 (47): (16510–16518). [PMID:36374940]
22. Jiang Ouyang, Qingyue Bu, Na Tao, Mingkai Chen, Haijun Liu, Jun Zhou, Jinggong Liu, Bo Deng, Na Kong, Xingcai Zhang, Tianfeng Chen, Yihai Cao, Wei Tao. (2022) A facile and general method for synthesis of antibiotic-free protein-based hydrogel: Wound dressing for the eradication of drug-resistant bacteria and biofilms. Bioactive Materials, 18 (446). [PMID:35415296]
23. Guofeng Ye, Siqi Huo, Cheng Wang, Qiu Shi, Lingfeng Yu, Zhitian Liu, Zhengping Fang, Hao Wang. (2021) A novel hyperbranched phosphorus-boron polymer for transparent, flame-retardant, smoke-suppressive, robust yet tough epoxy resins. COMPOSITES PART B-ENGINEERING, 227 (109395). [PMID:]

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Bis[tetrakis(hydroxymethyl)phosphonium] sulfate solution - 75% in water, high purity , CAS No.55566-30-8