Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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B129453-1g | 1g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $21.90 | |
B129453-5g | 5g | In stock | $82.90 | |
B129453-25g | 25g | In stock | $373.90 | |
B129453-100g | 100g | In stock | $1,344.90 | |
B129453-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $6,050.90 |
Na + /K + -ATPase inhibitor
Synonyms | LACO | Neolax | UNII-10X0709Y6I | Womans Laxative | CCRIS 8864 | SMR000058226 | Stadalax | Bisacodyl Laxative | Deficol | MFCD00038039 | The Magic Bullet | Carters Little Pills | Di-(4-acetoxyphenyl)-2-pyridylmethane | Sanvacual | BISACODYL (EP MONOGRAPH) |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Bisacodyl is a hygroscopic diphenol which has been implicated in the inhibition of (Na+K)ATPase, the increase of mucosal PGE2, and the activation of adenyl cyclase in rat intestine studies.Na + /K + -ATPase inhibitor. Increases mucosal PG2E levels. Stimul |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Bisacodyl (INN) is a stimulant laxative drug that works directly on the colon to produce a bowel movement. application: Bisacodyl is used in the inhibition of (Na+K)ATPase, the increase of mucosal PGE2, and the activation of adenyl cyclase in rat intestine studies. It is used as a laxative drug. It is typically prescribed for relief of constipation. |
ALogP | 3.8 |
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IUPAC Name | [4-[(4-acetyloxyphenyl)-pyridin-2-ylmethyl]phenyl] acetate |
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INCHI | InChI=1S/C22H19NO4/c1-15(24)26-19-10-6-17(7-11-19)22(21-5-3-4-14-23-21)18-8-12-20(13-9-18)27-16(2)25/h3-14,22H,1-2H3 |
InChi Key | KHOITXIGCFIULA-UHFFFAOYSA-N |
Canonical SMILES | CC(=O)OC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC(=O)C)C3=CC=CC=N3 |
Isomeric SMILES | CC(=O)OC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC(=O)C)C3=CC=CC=N3 |
WGK Germany | 3 |
RTECS | SM8750000 |
PubChem CID | 2391 |
Molecular Weight | 361.39 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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K2201082 | Certificate of Analysis | Aug 22, 2024 | B129453 |
K2201083 | Certificate of Analysis | Aug 22, 2024 | B129453 |
K2201187 | Certificate of Analysis | Aug 22, 2024 | B129453 |
K2201188 | Certificate of Analysis | Aug 22, 2024 | B129453 |
E1504022 | Certificate of Analysis | Dec 07, 2022 | B129453 |
Solubility | Soluble in alcohol (slightly), ether (slightly), chloroform, and acetone. Insoluble in water. |
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Sensitivity | Heat sensitive |
Melt Point(°C) | 134 °C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | SM8750000 |
Merck Index | 1242 |
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