Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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B113845-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $9.90 | |
B113845-25mg | 25mg | In stock | $25.90 | |
B113845-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $83.90 | |
B113845-500mg | 500mg | In stock | $378.90 |
Cell-permeable, adenine-thymine selective DNA fluorescent stain. DNA minor groove-directed agent.
Synonyms | Hoechst 33342 | 23491-52-3 | Bisbenzimide | Hoe 33342 | Bisbenzimide ethoxide | 2'-(4-Ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole | 2,5'-Bi-1H-benzimidazole, 2'-(4-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)- | 99KZS6CNZX | 2'-(4-ethoxyphenyl)-5 |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Cell permeable: yes ,Product does not compete with ATP ,Reversible: no ,Primary Target ,Adenine-thymine-specific fluorescent stain |
Storage Temp | Protected from light,Store at -20°C |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Cell-permeable, adenine-thymine-specific fluorescent stain. Useful for staining DNA, chromosomes, and nuclei for fluorescence microscopy and flow cytometry applications. Useful for the simultaneous study of the cell cycle and apoptosis in unfixed cells. Induces cell differentiation. H 33342 and the related compound H 33258 (Cat. No. 382061) have been used in conjunction with RNA aptamers in the 5′ untranslated region (UTR) to control expression of transfected gene constructs. Exhibits a 10-fold greater cell-permeability than H 33258. Cell-permeable adenine-thymidine specific fluorescent stain. Useful for staining DNA, chromosomes or nuclei for fluorescence microscopy and flow cytometry applications. DNA-bound dye has an excitation maximum of 358 nm and an emission maximum of 460 nm. Useful for the simultaneous study of the cell cycle and apoptosis in unfixed cells. Induces cell differentiation. H33342 and the related compound H33258 (Cat. No. 382061) have been used in conjunction with RNA aptamers in the 5′ untranslated region (UTR) to control expression of transfected gene constructs. Exhibits a 10 fold greater cell-permeability than H 33258. |
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IUPAC Name | 2-(4-ethoxyphenyl)-6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazole |
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INCHI | InChI=1S/C27H28N6O/c1-3-34-21-8-4-18(5-9-21)26-28-22-10-6-19(16-24(22)30-26)27-29-23-11-7-20(17-25(23)31-27)33-14-12-32(2)13-15-33/h4-11,16-17H,3,12-15H2,1-2H3,(H,28,30)(H,29,31) |
InChi Key | PRDFBSVERLRRMY-UHFFFAOYSA-N |
Canonical SMILES | CCOC1=CC=C(C=C1)C2=NC3=C(N2)C=C(C=C3)C4=NC5=C(N4)C=C(C=C5)N6CCN(CC6)C |
Isomeric SMILES | CCOC1=CC=C(C=C1)C2=NC3=C(N2)C=C(C=C3)C4=NC5=C(N4)C=C(C=C5)N6CCN(CC6)C |
WGK Germany | 3 |
Alternate CAS | 875756-97-1 |
PubChem CID | 1464 |
Molecular Weight | 561.93(anhydrous basis) |
Beilstein | 1234011 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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C2004089 | Certificate of Analysis | Dec 12, 2023 | B113845 |
F2228081 | Certificate of Analysis | Jun 09, 2022 | B113845 |
F2228099 | Certificate of Analysis | Jun 09, 2022 | B113845 |
F2228100 | Certificate of Analysis | Jun 09, 2022 | B113845 |
H2426085 | Certificate of Analysis | Nov 08, 2021 | B113845 |
Solubility | H2O: 20 mg/mL,phosphate buffer: precipitates |
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Sensitivity | light sensitive |
Pictogram(s) | GHS08, GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H335:May cause respiratory irritation H341:Suspected of causing genetic defects H302:Harmful if swallowed |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P281:Use personal protective equipment as required. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
1. Cheng Shen, Yachao Li, Zenan Zeng, Yiming Liu, Yini Xu, Kefurong Deng, Beiling Guo, Dongzhe Zou, Liguo Liu, Xiaoyu Liang, Xianghui Xu. (2023) Systemic Administration with Bacteria-Inspired Nanosystems for Targeted Oncolytic Therapy and Antitumor Immunomodulation. ACS Nano, 17 (24): (25638–25655). [PMID:38064380] |
2. Zihan He, Haoying Song, Jingjing Cheng, Wenxiu Qiu, Junjie Hu, Zhenpeng Qiu, Qi Wang, Cong Chang, Guohua Zheng, Yan Meng. (2023) Selenium Nanoparticles Stabilized by β-Glucan Nanotubes from Black Fungus and Their Effects on the Proliferation, Apoptosis, and Cell Cycle of HepG2 Cells. ACS Omega, [PMID:38075754] |
3. Yao Yuying, Wang Yeru, Zhu Jingru, Guo Zhiqiang, Li Zongqiang, Li Qianru, Liu Su, Wang Yu, Yu Jinghua, Huang Jiadong. (2023) A spatially-controlled DNA triangular prism nanomachine for AND-gated intracellular imaging of ATP in acidic microenvironment. MICROCHIMICA ACTA, 190 (11): (1-9). [PMID:37837554] |
4. Lianxue Zhang, Jianxiang Huang, Damiano Buratto, Panli Han, Zaixing Yang, Ruhong Zhou. (2023) A pH-responsive nanoparticle delivery system containing dihydralazine and doxorubicin-based prodrug for enhancing antitumor efficacy. Aggregate, 5 (1): (e434). [PMID:16580887] |
5. Gang Liu, Mingyu Liu, Xiujing Li, Xiaorong Ye, Kaiming Cao, Yangzhong Liu, Yue Yu. (2023) Peroxide-Simulating and GSH-Depleting Nanozyme for Enhanced Chemodynamic/Photodynamic Therapy via Induction of Multisource ROS. ACS Applied Materials & Interfaces, 15 (41): (47955–47968). [PMID:37812458] |
6. Liang Liang, Jin Ren, Jun Dai, Jianyun Liu, Lifang Zhang, Donglin Li, Chao Yang, Jingmou Yu. (2023) Layered double hydroxides - poloxamer 188 nanocomposites based on exfoliation reassembling for improved cellular uptake and controlled delivery of methotrexate. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, [PMID:37577952] |
7. Xin Wang, Jinshuang Hu, Hua Wei, Zihan Li, Jian Liu, Jie Zhang, Shenghong Yang. (2023) Ultra-fast solvent-free protocol remodels the large-scale synthesis of carbon dots for nucleolus-targeting and white light-emitting diodes. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 649 (785). [PMID:37385043] |
8. Jingmou Yu, Liangliang Wang, Yun Ling, Xin Xiao, Juntao Gong, Hongguang Jin, Jing Xu, Pu Chen, Xin Xie, Lei Zhang. (2023) Peptide-modified bioresponsive chondroitin sulfate micelles for targeted doxorubicin delivery in triple-negative breast cancer. COLLOIDS AND SURFACES B-BIOINTERFACES, 227 (113381). [PMID:37257299] |
9. Zheng Hua, Xuedi Zhang, Yannan Chen, Ronggang Liu, Yu Li, Jiaxuan Li, Donghong Liu, Mingqian Tan. (2023) A bifunctional hepatocyte-mitochondrion targeting nanosystem for effective astaxanthin delivery to the liver. FOOD CHEMISTRY, 424 (136439). [PMID:37245472] |
10. Rui Chang, Rongrong Fu, Yujiao Huang, Jibing Zhang, Changshun Feng, Rui Wang, Hui Yan, Guangyong Li, Xiaohong Chu, Fengjiao Yuan, Dianlong Jia, Jun Li. (2023) Codelivery of TRAIL and Mitomycin C via Liposomes Shows Improved Antitumor Effect on TRAIL-Resistant Tumors. MOLECULAR PHARMACEUTICS, [PMID:37134184] |
11. Yong Wang, Jia-Ying Ji, Kai Guo, Tao Zhang, Xin-Cao Zhong, Ze-Ming Zhuang, Yu-Fan Zhong, Xiao-Ying Lin, Yong-Zhong Du, Jian Chen, Wei Qiang Tan. (2023) Gene liposome nanocomplex-loaded dermal substitute promotes diabetic chronic wound healing and angiogenesis in rat. BIOMEDICINE & PHARMACOTHERAPY, 163 (114794). [PMID:37121150] |
12. Xuelian Wang, Hongye Cai, Xinyu Huang, Zhuhang Lu, Luxi Zhang, Junjie Hu, Daizhi Tian, Jiyu Fu, Guizhi Zhang, Yan Meng, Guohua Zheng, Cong Chang. (2023) Formulation and evaluation of a two-stage targeted liposome coated with hyaluronic acid for improving lung cancer chemotherapy and overcoming multidrug resistance. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 34 (14): (1928-1951). [PMID:37060335] |
13. Zhang Yufei, Cheng Qian, Xue Yuhao, Yao Kai, Syeda Madiha Zahra, Xu Jian, Wu Jianheng, Wang Zhenjie, Tang Longguang, Mu Qingchun. (2023) LAT1 targeted brain delivery of temozolomide and sorafenib for effective glioma therapy. Nano Research, (1-9). [PMID:] |
14. Yanan Li, Weikang Liang, Chenghua Li. (2023) Exogenous adenosine and/or guanosine enhances tetracycline sensitivity of persister cells. MICROBIOLOGICAL RESEARCH, 270 (127321). [PMID:36773473] |
15. Delong Hou, Yong Xu, Jun Yan, Qi Zeng, Zhonghui Wang, Yi Chen. (2023) Intracellularly Self-Assembled 2D Materials Induce Apoptotic Cell Death by Impeding Cytosolic Transport. ACS Nano, 17 (3): (3055–3063). [PMID:36688625] |
16. Jingmou Yu, Liangliang Wang, Xin Xie, Wenjing Zhu, Zhineng Lei, Linghui Lv, Hongling Yu, Jing Xu, Jin Ren. (2023) Multifunctional Nanoparticles Codelivering Doxorubicin and Amorphous Calcium Carbonate Preloaded with Indocyanine Green for Enhanced Chemo-Photothermal Cancer Therapy. International Journal of Nanomedicine, [PMID:36700147] |
17. Lu Lu, Hongyuan Chen, Longkun Wang, Lin Zhao, Yanna Cheng, Aijun Wang, Fengshan Wang, Xinke Zhang. (2023) A Dual Receptor Targeting- and BBB Penetrating- Peptide Functionalized Polyethyleneimine Nanocomplex for Secretory Endostatin Gene Delivery to Malignant Glioma. International Journal of Nanomedicine, [PMID:33209022] |
18. Hongyan Cui, Ming Zhang, Liuwei Zhang, Haidong Li, Yue Wang, Yan Zhao, Qixian Chen, Jingyun Wang. (2023) pH-responsive organic/inorganic hybrid nanocolloids for transcellular delivery of ribonucleolytic payloads toward targeted anti-glioma therapy. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 634 (388). [PMID:36542969] |
19. Ren Jin, Liang Liang, Yang Yongqing, Liu Xiang, Li Weidong, Liu Wenbo, Wang Yali, Yu Jingmou. (2023) Assembling drug-loaded-layered double hydroxide nanohybrids with poloxamer 188 for improved cellular uptake and in vitro efficacy. JOURNAL OF MATERIALS RESEARCH, 38 (2): (337-349). [PMID:] |
20. Zheng Hua, Xuedi Zhang, Xue Zhao, Bei-Wei Zhu, Donghong Liu, Mingqian Tan. (2023) Hepatic-targeted delivery of astaxanthin for enhanced scavenging free radical scavenge and preventing mitochondrial depolarization. FOOD CHEMISTRY, 406 (135036). [PMID:36459794] |
21. Xin Wang, Jinshuang Hu, Boxuan Yao, Hua Wei, Caiyun Zhang, Jiarui Zhou, Jian Liu, Shenghong Yang. (2023) Bridging environmental and biological monitoring: Constructing platform for hexavalent chromium detection and cancer-cells screening based on red fluorescent carbonized polymer dots. CHEMICAL ENGINEERING JOURNAL, 451 (138524). [PMID:] |
22. Hongyan Cui, Liuwei Zhang, Shuang Zeng, Yu Wang, Zhen Li, Jingyun Wang, Qixian Chen. (2022) Charge-Reversible Pro-Ribonuclease Enveloped in Virus-like Synthetic Nanocapsules for Systemic Treatment of Intractable Glioma. ACS Applied Materials & Interfaces, 14 (27): (30493–30506). [PMID:35657733] |
23. Huijuan Zhang, Qingqing He, Jingjing Wang, Yaping Wang, Xiangyang Xuan, Mingli Sui, Zhenzhong Zhang, Lin Hou. (2022) Biomimetic micelles to accurately regulate the inflammatory microenvironment for glomerulonephritis treatment. PHARMACOLOGICAL RESEARCH, 181 (106263). [PMID:35597383] |
24. Jianhua He, Xiaoju Zhou, Fengfei Xu, Hongliang He, Shuangyan Ma, Xinyue Liu, Mengyuan Zhang, Wenli Zhang, Jianping Liu. (2022) Anchoring β-CD on simvastatin-loaded rHDL for selective cholesterol crystals dissolution and enhanced anti-inflammatory effects in macrophage/foam cells. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 174 (144). [PMID:35447349] |
25. Jianhua He, Wenli Zhang, Xiaoju Zhou, Fengfei Xu, Jiahui Zou, Qiqi Zhang, Yi Zhao, Hongliang He, Hu Yang, Jianping Liu. (2023) Reactive oxygen species (ROS)-responsive size-reducible nanoassemblies for deeper atherosclerotic plaque penetration and enhanced macrophage-targeted drug delivery. Bioactive Materials, 19 (115). [PMID:35475030] |
26. Xiangrong Tian, Li Ruan, Shengwang Zhou, Lin Wu, Jin Cao, Xueyong Qi, Xin Zhang, Song Shen. (2022) Appropriate Size of Fe3O4 Nanoparticles for Cancer Therapy by Ferroptosis. ACS Applied Bio Materials, 5 (4): (1692–1699). [PMID:35297253] |
27. Xinming Zhang, Ruijuan Lv, Lixia Chen, Ruimeng Sun, Yang Zhang, Rongtian Sheng, Ting Du, Yuhan Li, Yanfei Qi. (2022) A Multifunctional Janus Electrospun Nanofiber Dressing with Biofluid Draining, Monitoring, and Antibacterial Properties for Wound Healing. ACS Applied Materials & Interfaces, 14 (11): (12984–13000). [PMID:35266385] |
28. Qing Hu, Jiayi Yao, Xiaoqin Wang, Yanfang Wang, Xiaoling Fu, Ju Ma, Han Lin, Jiaqi Xu, Longhua Shen, Xiangbin Yu. (2022) Combinational Chemoimmunotherapy for Breast Cancer by Codelivery of Doxorubicin and PD-L1 siRNA Using a PAMAM-Incorporated Liposomal Nanoplatform. ACS Applied Materials & Interfaces, 14 (7): (8782–8792). [PMID:35138103] |
29. Yang Zhang, Lixia Chen, Ruimeng Sun, Ruijuan Lv, Ting Du, Yuhan Li, Xinming Zhang, Rongtian Sheng, Yanfei Qi. (2022) Multienzymatic Antioxidant Activity of Manganese-Based Nanoparticles for Protection against Oxidative Cell Damage. ACS Biomaterials Science & Engineering, 8 (2): (638–648). [PMID:35076222] |
30. Duo Liang, Wentao Su, Xue Zhao, Jiaxuan Li, Zheng Hua, Song Miao, Mingqian Tan. (2022) Microfluidic Fabrication of pH-Responsive Nanoparticles for Encapsulation and Colon-Target Release of Fucoxanthin. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70 (1): (124–135). [PMID:34963047] |
31. Lixia Chen, Yang Zhang, Xinming Zhang, Ruijuan Lv, Rongtian Sheng, Ruimeng Sun, Ting Du, Yuhan Li, Yanfei Qi. (2022) A GdW10@PDA-CAT Sensitizer with High-Z Effect and Self-Supplied Oxygen for Hypoxic-Tumor Radiotherapy. MOLECULES, 27 (1): (128). [PMID:35011360] |
32. Cui Zixin, Zhang Miaomiao, Geng Songmei, Niu Xinwu, Wang Xiaopeng, Zhu Yanyan, Ye Feng, Liu Chengcheng. (2021) Antifungal Effect of Antimicrobial Photodynamic Therapy Mediated by Haematoporphyrin Monomethyl Ether and Aloe Emodin on Malassezia furfur. Frontiers in Microbiology, 12 [PMID:34867868] |
33. Qin Wang, Kai-Ni Wei, Shu-Zhen Huang, Qing Tang, Zhu Tao, Ying Huang. (2021) “Turn-Off” Supramolecular Fluorescence Array Sensor for Heavy Metal Ion Identification. ACS Omega, 6 (46): (31229–31235). [PMID:34841166] |
34. Guijie Wei, Jianhua Chen, Ziqi Jing, Yanyi Li, Zhihui Li, Wei Zheng, Xiurui Sun, Wenwen Zhao, Zhe Zhang, Xue Wang, Hongcui Han, Chu Li, Yujie Zhang, Pengkai Ma. (2022) Glucose transporter 1 (GLUT1)-targeting and hypoxia-activated mitochondria-specific chemo-thermal therapy via a glycosylated poly(amido amine)/celastrol (PAMAM/Cel) complex. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 608 (1355). [PMID:34742058] |
1. Fahkrajang W et al.. (2021) Bovine respiratory coronavirus enhances bacterial adherence by upregulating expression of cellular receptors on bovine respiratory epithelial cells.. Vet Microbiol, 255 (109017). [PMID:33639390] |
2. Sudaryatma PE et al.. (2020) Bovine Respiratory Syncytial Virus Decreased Pasteurella multocida Adherence by Downregulating the Expression of Intercellular Adhesion Molecule-1 on the Surface of Upper Respiratory Epithelial Cells.. Vet Microbiol, 246 (108748). [PMID:32605748] |
3. Sudaryatma PE et al.. (2019) Co-infection of epithelial cells established from the upper and lower bovine respiratory tract with bovine respiratory syncytial virus and bacteria.. Vet Microbiol, 235 (80-85). [PMID:31282382] |
4. McCulloch A et al.. (2020) Endothelialized silicone aneurysm models for in vitro evaluation of flow diverters.. J Neurointerv Surg, [PMID:33106319] |
5. Lorenzoni M et al.. (2022) ETS-related gene (ERG) undermines genome stability in mouse prostate progenitors via Gsk3β dependent Nkx3.1 degradation.. Cancer Lett, 534 (215612). [PMID:35259458] |
6. Cambuli F et al.. (2022) Intra-epithelial non-canonical Activin A signaling safeguards prostate progenitor quiescence.. EMBO Rep, 23 (5): (e54049). [PMID:35253958] |
7. Pazinato FM et al.. (2019) Immunolocalization of Leptin and its Receptor (ObR-b) in Equine Placenta at Term and Plasma Level Measurement in the Late Gestation.. J Equine Vet Sci, 78 (1-5). [PMID:31203970] |
8. Dos Santos CJ et al.. (2018) Impact of human cytomegalovirus on glioblastoma cell viability and chemotherapy treatment.. J Gen Virol, 99 (9): (1274-1285). [PMID:30045780] |
9. Tian NX et al.. (2018) KChIP3 N-Terminal 31-50 Fragment Mediates Its Association with TRPV1 and Alleviates Inflammatory Hyperalgesia in Rats.. J Neurosci, 38 (7): (1756-1773). [PMID:29335353] |
10. Ming-Yan Y et al.. (2019) Liraglutide inhibits the apoptosis of human nucleus pulposus cells induced by high glucose through PI3K/Akt/caspase-3 signaling pathway.. Biosci Rep, 39 (8): [PMID:31383790] |
11. Rodríguez-Nuevo A et al.. (2022) Oocytes maintain ROS-free mitochondrial metabolism by suppressing complex I.. Nature, 607 (7920): (756-761). [PMID:35859172] |
12. Kumar M et al.. (2020) Quinacrine inhibits GSTA1 activity and induces apoptosis through G1/S arrest and generation of ROS in human non-small cell lung cancer cell lines.. Oncotarget, 11 (18): (1603-1617). [PMID:32405336] |
13. Cheng Shen, Yachao Li, Zenan Zeng, Yiming Liu, Yini Xu, Kefurong Deng, Beiling Guo, Dongzhe Zou, Liguo Liu, Xiaoyu Liang, Xianghui Xu. (2023) Systemic Administration with Bacteria-Inspired Nanosystems for Targeted Oncolytic Therapy and Antitumor Immunomodulation. ACS Nano, 17 (24): (25638–25655). [PMID:38064380] |
14. Zihan He, Haoying Song, Jingjing Cheng, Wenxiu Qiu, Junjie Hu, Zhenpeng Qiu, Qi Wang, Cong Chang, Guohua Zheng, Yan Meng. (2023) Selenium Nanoparticles Stabilized by β-Glucan Nanotubes from Black Fungus and Their Effects on the Proliferation, Apoptosis, and Cell Cycle of HepG2 Cells. ACS Omega, [PMID:38075754] |
15. Yao Yuying, Wang Yeru, Zhu Jingru, Guo Zhiqiang, Li Zongqiang, Li Qianru, Liu Su, Wang Yu, Yu Jinghua, Huang Jiadong. (2023) A spatially-controlled DNA triangular prism nanomachine for AND-gated intracellular imaging of ATP in acidic microenvironment. MICROCHIMICA ACTA, 190 (11): (1-9). [PMID:37837554] |
16. Lianxue Zhang, Jianxiang Huang, Damiano Buratto, Panli Han, Zaixing Yang, Ruhong Zhou. (2023) A pH-responsive nanoparticle delivery system containing dihydralazine and doxorubicin-based prodrug for enhancing antitumor efficacy. Aggregate, 5 (1): (e434). [PMID:16580887] |
17. Gang Liu, Mingyu Liu, Xiujing Li, Xiaorong Ye, Kaiming Cao, Yangzhong Liu, Yue Yu. (2023) Peroxide-Simulating and GSH-Depleting Nanozyme for Enhanced Chemodynamic/Photodynamic Therapy via Induction of Multisource ROS. ACS Applied Materials & Interfaces, 15 (41): (47955–47968). [PMID:37812458] |
18. Liang Liang, Jin Ren, Jun Dai, Jianyun Liu, Lifang Zhang, Donglin Li, Chao Yang, Jingmou Yu. (2023) Layered double hydroxides - poloxamer 188 nanocomposites based on exfoliation reassembling for improved cellular uptake and controlled delivery of methotrexate. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, [PMID:37577952] |
19. Xin Wang, Jinshuang Hu, Hua Wei, Zihan Li, Jian Liu, Jie Zhang, Shenghong Yang. (2023) Ultra-fast solvent-free protocol remodels the large-scale synthesis of carbon dots for nucleolus-targeting and white light-emitting diodes. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 649 (785). [PMID:37385043] |
20. Jingmou Yu, Liangliang Wang, Yun Ling, Xin Xiao, Juntao Gong, Hongguang Jin, Jing Xu, Pu Chen, Xin Xie, Lei Zhang. (2023) Peptide-modified bioresponsive chondroitin sulfate micelles for targeted doxorubicin delivery in triple-negative breast cancer. COLLOIDS AND SURFACES B-BIOINTERFACES, 227 (113381). [PMID:37257299] |
21. Zheng Hua, Xuedi Zhang, Yannan Chen, Ronggang Liu, Yu Li, Jiaxuan Li, Donghong Liu, Mingqian Tan. (2023) A bifunctional hepatocyte-mitochondrion targeting nanosystem for effective astaxanthin delivery to the liver. FOOD CHEMISTRY, 424 (136439). [PMID:37245472] |
22. Rui Chang, Rongrong Fu, Yujiao Huang, Jibing Zhang, Changshun Feng, Rui Wang, Hui Yan, Guangyong Li, Xiaohong Chu, Fengjiao Yuan, Dianlong Jia, Jun Li. (2023) Codelivery of TRAIL and Mitomycin C via Liposomes Shows Improved Antitumor Effect on TRAIL-Resistant Tumors. MOLECULAR PHARMACEUTICS, [PMID:37134184] |
23. Yong Wang, Jia-Ying Ji, Kai Guo, Tao Zhang, Xin-Cao Zhong, Ze-Ming Zhuang, Yu-Fan Zhong, Xiao-Ying Lin, Yong-Zhong Du, Jian Chen, Wei Qiang Tan. (2023) Gene liposome nanocomplex-loaded dermal substitute promotes diabetic chronic wound healing and angiogenesis in rat. BIOMEDICINE & PHARMACOTHERAPY, 163 (114794). [PMID:37121150] |
24. Xuelian Wang, Hongye Cai, Xinyu Huang, Zhuhang Lu, Luxi Zhang, Junjie Hu, Daizhi Tian, Jiyu Fu, Guizhi Zhang, Yan Meng, Guohua Zheng, Cong Chang. (2023) Formulation and evaluation of a two-stage targeted liposome coated with hyaluronic acid for improving lung cancer chemotherapy and overcoming multidrug resistance. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 34 (14): (1928-1951). [PMID:37060335] |
25. Zhang Yufei, Cheng Qian, Xue Yuhao, Yao Kai, Syeda Madiha Zahra, Xu Jian, Wu Jianheng, Wang Zhenjie, Tang Longguang, Mu Qingchun. (2023) LAT1 targeted brain delivery of temozolomide and sorafenib for effective glioma therapy. Nano Research, (1-9). [PMID:] |
26. Yanan Li, Weikang Liang, Chenghua Li. (2023) Exogenous adenosine and/or guanosine enhances tetracycline sensitivity of persister cells. MICROBIOLOGICAL RESEARCH, 270 (127321). [PMID:36773473] |
27. Delong Hou, Yong Xu, Jun Yan, Qi Zeng, Zhonghui Wang, Yi Chen. (2023) Intracellularly Self-Assembled 2D Materials Induce Apoptotic Cell Death by Impeding Cytosolic Transport. ACS Nano, 17 (3): (3055–3063). [PMID:36688625] |
28. Jingmou Yu, Liangliang Wang, Xin Xie, Wenjing Zhu, Zhineng Lei, Linghui Lv, Hongling Yu, Jing Xu, Jin Ren. (2023) Multifunctional Nanoparticles Codelivering Doxorubicin and Amorphous Calcium Carbonate Preloaded with Indocyanine Green for Enhanced Chemo-Photothermal Cancer Therapy. International Journal of Nanomedicine, [PMID:36700147] |
29. Lu Lu, Hongyuan Chen, Longkun Wang, Lin Zhao, Yanna Cheng, Aijun Wang, Fengshan Wang, Xinke Zhang. (2023) A Dual Receptor Targeting- and BBB Penetrating- Peptide Functionalized Polyethyleneimine Nanocomplex for Secretory Endostatin Gene Delivery to Malignant Glioma. International Journal of Nanomedicine, [PMID:33209022] |
30. Hongyan Cui, Ming Zhang, Liuwei Zhang, Haidong Li, Yue Wang, Yan Zhao, Qixian Chen, Jingyun Wang. (2023) pH-responsive organic/inorganic hybrid nanocolloids for transcellular delivery of ribonucleolytic payloads toward targeted anti-glioma therapy. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 634 (388). [PMID:36542969] |
31. Ren Jin, Liang Liang, Yang Yongqing, Liu Xiang, Li Weidong, Liu Wenbo, Wang Yali, Yu Jingmou. (2023) Assembling drug-loaded-layered double hydroxide nanohybrids with poloxamer 188 for improved cellular uptake and in vitro efficacy. JOURNAL OF MATERIALS RESEARCH, 38 (2): (337-349). [PMID:] |
32. Zheng Hua, Xuedi Zhang, Xue Zhao, Bei-Wei Zhu, Donghong Liu, Mingqian Tan. (2023) Hepatic-targeted delivery of astaxanthin for enhanced scavenging free radical scavenge and preventing mitochondrial depolarization. FOOD CHEMISTRY, 406 (135036). [PMID:36459794] |
33. Xin Wang, Jinshuang Hu, Boxuan Yao, Hua Wei, Caiyun Zhang, Jiarui Zhou, Jian Liu, Shenghong Yang. (2023) Bridging environmental and biological monitoring: Constructing platform for hexavalent chromium detection and cancer-cells screening based on red fluorescent carbonized polymer dots. CHEMICAL ENGINEERING JOURNAL, 451 (138524). [PMID:] |
34. Hongyan Cui, Liuwei Zhang, Shuang Zeng, Yu Wang, Zhen Li, Jingyun Wang, Qixian Chen. (2022) Charge-Reversible Pro-Ribonuclease Enveloped in Virus-like Synthetic Nanocapsules for Systemic Treatment of Intractable Glioma. ACS Applied Materials & Interfaces, 14 (27): (30493–30506). [PMID:35657733] |
35. Huijuan Zhang, Qingqing He, Jingjing Wang, Yaping Wang, Xiangyang Xuan, Mingli Sui, Zhenzhong Zhang, Lin Hou. (2022) Biomimetic micelles to accurately regulate the inflammatory microenvironment for glomerulonephritis treatment. PHARMACOLOGICAL RESEARCH, 181 (106263). [PMID:35597383] |
36. Jianhua He, Xiaoju Zhou, Fengfei Xu, Hongliang He, Shuangyan Ma, Xinyue Liu, Mengyuan Zhang, Wenli Zhang, Jianping Liu. (2022) Anchoring β-CD on simvastatin-loaded rHDL for selective cholesterol crystals dissolution and enhanced anti-inflammatory effects in macrophage/foam cells. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 174 (144). [PMID:35447349] |
37. Jianhua He, Wenli Zhang, Xiaoju Zhou, Fengfei Xu, Jiahui Zou, Qiqi Zhang, Yi Zhao, Hongliang He, Hu Yang, Jianping Liu. (2023) Reactive oxygen species (ROS)-responsive size-reducible nanoassemblies for deeper atherosclerotic plaque penetration and enhanced macrophage-targeted drug delivery. Bioactive Materials, 19 (115). [PMID:35475030] |
38. Xiangrong Tian, Li Ruan, Shengwang Zhou, Lin Wu, Jin Cao, Xueyong Qi, Xin Zhang, Song Shen. (2022) Appropriate Size of Fe3O4 Nanoparticles for Cancer Therapy by Ferroptosis. ACS Applied Bio Materials, 5 (4): (1692–1699). [PMID:35297253] |
39. Xinming Zhang, Ruijuan Lv, Lixia Chen, Ruimeng Sun, Yang Zhang, Rongtian Sheng, Ting Du, Yuhan Li, Yanfei Qi. (2022) A Multifunctional Janus Electrospun Nanofiber Dressing with Biofluid Draining, Monitoring, and Antibacterial Properties for Wound Healing. ACS Applied Materials & Interfaces, 14 (11): (12984–13000). [PMID:35266385] |
40. Qing Hu, Jiayi Yao, Xiaoqin Wang, Yanfang Wang, Xiaoling Fu, Ju Ma, Han Lin, Jiaqi Xu, Longhua Shen, Xiangbin Yu. (2022) Combinational Chemoimmunotherapy for Breast Cancer by Codelivery of Doxorubicin and PD-L1 siRNA Using a PAMAM-Incorporated Liposomal Nanoplatform. ACS Applied Materials & Interfaces, 14 (7): (8782–8792). [PMID:35138103] |
41. Yang Zhang, Lixia Chen, Ruimeng Sun, Ruijuan Lv, Ting Du, Yuhan Li, Xinming Zhang, Rongtian Sheng, Yanfei Qi. (2022) Multienzymatic Antioxidant Activity of Manganese-Based Nanoparticles for Protection against Oxidative Cell Damage. ACS Biomaterials Science & Engineering, 8 (2): (638–648). [PMID:35076222] |
42. Duo Liang, Wentao Su, Xue Zhao, Jiaxuan Li, Zheng Hua, Song Miao, Mingqian Tan. (2022) Microfluidic Fabrication of pH-Responsive Nanoparticles for Encapsulation and Colon-Target Release of Fucoxanthin. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70 (1): (124–135). [PMID:34963047] |
43. Lixia Chen, Yang Zhang, Xinming Zhang, Ruijuan Lv, Rongtian Sheng, Ruimeng Sun, Ting Du, Yuhan Li, Yanfei Qi. (2022) A GdW10@PDA-CAT Sensitizer with High-Z Effect and Self-Supplied Oxygen for Hypoxic-Tumor Radiotherapy. MOLECULES, 27 (1): (128). [PMID:35011360] |
44. Cui Zixin, Zhang Miaomiao, Geng Songmei, Niu Xinwu, Wang Xiaopeng, Zhu Yanyan, Ye Feng, Liu Chengcheng. (2021) Antifungal Effect of Antimicrobial Photodynamic Therapy Mediated by Haematoporphyrin Monomethyl Ether and Aloe Emodin on Malassezia furfur. Frontiers in Microbiology, 12 [PMID:34867868] |
45. Qin Wang, Kai-Ni Wei, Shu-Zhen Huang, Qing Tang, Zhu Tao, Ying Huang. (2021) “Turn-Off” Supramolecular Fluorescence Array Sensor for Heavy Metal Ion Identification. ACS Omega, 6 (46): (31229–31235). [PMID:34841166] |
46. Guijie Wei, Jianhua Chen, Ziqi Jing, Yanyi Li, Zhihui Li, Wei Zheng, Xiurui Sun, Wenwen Zhao, Zhe Zhang, Xue Wang, Hongcui Han, Chu Li, Yujie Zhang, Pengkai Ma. (2022) Glucose transporter 1 (GLUT1)-targeting and hypoxia-activated mitochondria-specific chemo-thermal therapy via a glycosylated poly(amido amine)/celastrol (PAMAM/Cel) complex. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 608 (1355). [PMID:34742058] |