The store will not work correctly when cookies are disabled.
Bisindolylmaleimide IV - 10mM in DMSO, high purity , CAS No.119139-23-0
Potent cell-permeable PKC inhibitor
Basic Description
| Synonyms | bisindolylmaleimide iv|119139-23-0|3,4-di(1H-indol-3-yl)-1H-pyrrole-2,5-dione|Arcyriarubin A|3,4-Bis(3-indolyl)maleimide|3,4-bis(1H-indol-3-yl)pyrrole-2,5-dione|3,4-Di-1H-indol-3-yl-1H-pyrrole-2,5-dione|1H-Pyrrole-2,5-dione, 3,4-di-1H-indol-3-yl-|BIM IV|C |
|---|
| Specifications & Purity | Moligand™, 10mM in DMSO |
|---|
| Biochemical and Physiological Mechanisms | Potent cell-permeable PKC inhibitor (IC 50 values are 0.1 - 0.55 μM). Inhibits PKA (IC 50 values are 2 - 11.8 µM). Noncompetitive nAChR antagonist. Shows less potent antinicotinic effects than Bisindolylmaleimide II . |
|---|
| Storage Temp | Store at -80°C |
|---|
| Shipped In | Ice chest + Ice pads |
|---|
| Grade | Moligand™ |
|---|
Names and Identifiers
| IUPAC Name | 3,4-bis(1H-indol-3-yl)pyrrole-2,5-dione |
|---|
| INCHI | InChI=1S/C20H13N3O2/c24-19-17(13-9-21-15-7-3-1-5-11(13)15)18(20(25)23-19)14-10-22-16-8-4-2-6-12(14)16/h1-10,21-22H,(H,23,24,25) |
|---|
| InChi Key | DQYBRTASHMYDJG-UHFFFAOYSA-N |
|---|
| Canonical SMILES | C1=CC=C2C(=C1)C(=CN2)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54 |
|---|
| Isomeric SMILES | C1=CC=C2C(=C1)C(=CN2)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54 |
|---|
| WGK Germany | 3 |
|---|
| PubChem CID | 2399 |
|---|
| Molecular Weight | 327.34 |
|---|
Chemical and Physical Properties
| Sensitivity | Air Sensitive,Heat Sensitive |
|---|
| Melt Point(°C) | 254 °C |
|---|
Solution Calculators
Molarity Calculator
Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator
Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
