Basic Description

Synonyms	BM 15766 sulfate \| 86621-94-5 \| 4-[2-[4-[3-(4-Chlorophenyl)-2-propenyl]-1-piperazinyl]ethyl]benzoic acid sulfate \| CHEMBL2172263 \| BM 15.766 \| 4-[2-[4-[(E)-3-(4-chlorophenyl)prop-2-enyl]piperazin-1-yl]ethyl]benzoic acid;sulfuric acid
Specifications & Purity	≥98%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Product Description	BM 15766 sulfate is a DHCR7 (dehydrocholesterol reductase) inhibitor. 7-dehydrocholesterol reductase catalyzes the last step of cholesterol synthesis.

Associated Targets(Human)

DHCR7 Tchem 7-dehydrocholesterol reductase (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Dhcr7 7-dehydrocholesterol reductase (10 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

IUPAC Name	4-[2-[4-[(E)-3-(4-chlorophenyl)prop-2-enyl]piperazin-1-yl]ethyl]benzoic acid;sulfuric acid
INCHI	InChI=1S/C22H25ClN2O2.H2O4S/c23-21-9-5-18(6-10-21)2-1-12-24-14-16-25(17-15-24)13-11-19-3-7-20(8-4-19)22(26)27;1-5(2,3)4/h1-10H,11-17H2,(H,26,27);(H2,1,2,3,4)/b2-1+;
InChi Key	OVMQIVIYKXXEIT-TYYBGVCCSA-N
Canonical SMILES	C1CN(CCN1CCC2=CC=C(C=C2)C(=O)O)CC=CC3=CC=C(C=C3)Cl.OS(=O)(=O)O
Isomeric SMILES	C1CN(CCN1CCC2=CC=C(C=C2)C(=O)O)C/C=C/C3=CC=C(C=C3)Cl.OS(=O)(=O)O
WGK Germany	3
PubChem CID	71312050
Molecular Weight	483

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10 results found

Lot Number	Certificate Type	Date	Item
F2330458	Certificate of Analysis	May 16, 2023	B337166
F2330461	Certificate of Analysis	May 16, 2023	B337166
F2330463	Certificate of Analysis	May 16, 2023	B337166
F2330464	Certificate of Analysis	May 16, 2023	B337166
F2330470	Certificate of Analysis	May 16, 2023	B337166
F2330517	Certificate of Analysis	May 16, 2023	B337166
F2330520	Certificate of Analysis	May 16, 2023	B337166
F2330528	Certificate of Analysis	May 16, 2023	B337166
F2330532	Certificate of Analysis	May 16, 2023	B337166
F2330590	Certificate of Analysis	May 16, 2023	B337166

Solubility	Soluble in DMSO at 4 mg/mL. Insoluble in water.
Melt Point(°C)	>300° C

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RIDADR	NONHforallmodesoftransport

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Determine the dilution needed to prepare a stock solution.

SKU	Size	Availability	Price
B337166-1mg	1mg	In stock	$180.90
B337166-5mg	5mg	In stock	$679.90
B337166-10mg	10mg	In stock	$1,222.90
B337166-25mg	25mg	In stock	$2,750.90
B337166-50mg	50mg	In stock	$4,951.90