BML-210 - 95%, high purity , CAS No.537034-17-6

  • ≥95%
Item Number
B275173
Grouped product items
SKUSizeAvailabilityPrice Qty
B275173-5mg
5mg
In stock
$64.90
B275173-25mg
25mg
In stock
$168.90
B275173-50mg
50mg
In stock
$271.90
B275173-100mg
100mg
In stock
$489.90

HDAC inhibitor

Basic Description

SynonymsSAOA | BML-210, >=98% (HPLC), powder | SCHEMBL146858 | BRD-K17820047-001-01-0 | EC-000.2274 | FT-0700481 | CHEBI:61077 | N1-(2-aminophenyl)-N8-phenyloctanediamide | N1-(2-aminophenyl)-N8-phenyl-octanediamide | A923367 | BCP16850 | DTXSID8066505 | N-(2-ami
Specifications & Purity≥95%
Biochemical and Physiological MechanismsHistone deacetylase (HDAC) inhibitor (IC 50 = 87 μM). Induces changes in gene expression profile. Antiproliferative activity in vitro .
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

BML-210 is a novel HDAC inhibitor, IC50 value: 5 μM。

Associated Targets(Human)

HDAC8 Tclin Histone deacetylase 8 (4516 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC10 Tclin Histone deacetylase 10 (801 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC2 Tclin Histone deacetylase 2 (3971 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC3 Tclin Histone deacetylase 3 (3654 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC4 Tclin Histone deacetylase 4 (2328 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC9 Tclin Histone deacetylase 9 (708 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC11 Tclin Histone deacetylase 11 (967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC7 Tclin Histone deacetylase 7 (1047 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MV4-11 (7307 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GM15850 (303 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac1 Histone deacetylase 1 (93 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac5 Histone deacetylase 5 (5 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HD1 Histone deacetylase (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name N'-(2-aminophenyl)-N-phenyloctanediamide
INCHI InChI=1S/C20H25N3O2/c21-17-12-8-9-13-18(17)23-20(25)15-7-2-1-6-14-19(24)22-16-10-4-3-5-11-16/h3-5,8-13H,1-2,6-7,14-15,21H2,(H,22,24)(H,23,25)
InChi Key RFLHBLWLFUFFDZ-UHFFFAOYSA-N
Canonical SMILES C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NC2=CC=CC=C2N
Isomeric SMILES C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NC2=CC=CC=C2N
PubChem CID 9543540
Molecular Weight 339.43

Certificates

Certificate of Analysis(COA)

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4 results found

Lot NumberCertificate TypeDateItem
I2202416Certificate of AnalysisJun 12, 2023 B275173
I2202417Certificate of AnalysisJun 12, 2023 B275173
I2202418Certificate of AnalysisJun 12, 2023 B275173
I2202409Certificate of AnalysisJun 12, 2023 B275173

Chemical and Physical Properties

SolubilitySoluble in DMSO to 50 mM and in ethanol to 25 mM (with warming)

Related Documents

References

1. Li L et al..  (2016)  Activating frataxin expression by repeat-targeted nucleic acids..  Nat Commun,  (10606).  [PMID:26842135]

Solution Calculators