BMS 345541 - ≥99%, high purity , CAS No.445430-58-0

Specifications & Purity: ≥99%

Item Number

B275312

Grouped product items
SKU	Size	Availability	Price
B275312-5mg	5mg	In stock	$88.90
B275312-10mg	10mg	In stock	$137.90
B275312-25mg	25mg	In stock	$276.90
B275312-50mg	50mg	In stock	$444.90
B275312-100mg	100mg	In stock	$801.90

Highly selective cell permeable IKK-2 and IKK-1 inhibitor

Basic Description

Synonyms	445430-58-0\|BMS-345541\|BMS-345541 free base\|BMS345541\|N1-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)ethane-1,2-diamine\|IKK Inhibitor III, BMS-345541\|IKK Inhibitor III\|BMS-345541(free base)\|1,2-Ethanediamine, N-(1,8-dimethylimidazo(1,2-a)quinoxalin-4-yl)-\|
Specifications & Purity	≥99%
Storage Temp	Store at -20°C,Desiccated
Shipped In	Dry ice

Names and Identifiers

IUPAC Name	N'-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)ethane-1,2-diamine
INCHI	InChI=1S/C14H17N5/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15/h3-4,7-8H,5-6,15H2,1-2H3,(H,16,18)
InChi Key	PSPFQEBFYXJZEV-UHFFFAOYSA-N
Canonical SMILES	CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN
Isomeric SMILES	CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN
PubChem CID	9813758
Molecular Weight	255.32

Certificates

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5 results found

Lot Number	Certificate Type	Date	Item
G2208195	Certificate of Analysis	Jun 07, 2022	B275312
G2208204	Certificate of Analysis	Jun 07, 2022	B275312
G2208296	Certificate of Analysis	Jun 07, 2022	B275312
G2208297	Certificate of Analysis	Jun 07, 2022	B275312
G2208336	Certificate of Analysis	Jun 07, 2022	B275312

References

1. Mirzaei R et al.. (2021) PD-1 independent of PD-L1 ligation promotes glioblastoma growth through the NF?B pathway.. Sci Adv, 7 (45): (eabh2148). [PMID:34739319]
2. Hahn A et al.. (2020) Serum amyloid A1 mediates myotube atrophy via Toll-like receptors.. J Cachexia Sarcopenia Muscle, 11 (103-119). [PMID:31441598]
3. Zhang Y et al.. (2017) The Unknown Aspect of BAFF: Inducing IL-35 Production by a CD5+CD1dhiFc?RIIbhiRegulatory B-Cell Subset in Lupus.. J Invest Dermatol, 137 (12): (2532-2543). [PMID:28844943]

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Basic Description