Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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B276089-5mg | 5mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $117.90 | |
B276089-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $197.90 | |
B276089-25mg | 25mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $444.90 | |
B276089-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $711.90 | |
B276089-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,137.90 |
Potent, selective RARα agonist
Synonyms | BMS 753 | 215307-86-1 | BMS753 | BMS-753 | 4-[[(2,3-Dihydro-1,1,3,3-tetramethyl-2-oxo-1H-inden-5-yl)carbonyl]amino]-benzoic acid | 4-[(1,1,3,3-tetramethyl-2-oxoindene-5-carbonyl)amino]benzoic acid | GTPL2650 | SCHEMBL7212759 | CHEMBL4792252 | BDBM36810 | EX-A7954 | AKOS0244576 |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Potent, selective retinoic acid receptor α agonist (K i = 2 nM). Antitumor agent. Active in vitro . |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of Retinoic acid receptor-α |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
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IUPAC Name | 4-[(1,1,3,3-tetramethyl-2-oxoindene-5-carbonyl)amino]benzoic acid |
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INCHI | InChI=1S/C21H21NO4/c1-20(2)15-10-7-13(11-16(15)21(3,4)19(20)26)17(23)22-14-8-5-12(6-9-14)18(24)25/h5-11H,1-4H3,(H,22,23)(H,24,25) |
InChi Key | KFBPBWUZXBYJDG-UHFFFAOYSA-N |
Canonical SMILES | CC1(C2=C(C=C(C=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)C(C1=O)(C)C)C |
Isomeric SMILES | CC1(C2=C(C=C(C=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)C(C1=O)(C)C)C |
WGK Germany | 3 |
Alternate CAS | 215307-86-1 |
PubChem CID | 9884820 |
Molecular Weight | 351.4 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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D2311133 | Certificate of Analysis | Jan 15, 2024 | B276089 |
D2311134 | Certificate of Analysis | Jan 15, 2024 | B276089 |
D2311138 | Certificate of Analysis | Jan 15, 2024 | B276089 |
D2311201 | Certificate of Analysis | Jan 15, 2024 | B276089 |
D2311212 | Certificate of Analysis | Jan 15, 2024 | B276089 |
D2311135 | Certificate of Analysis | Mar 14, 2023 | B276089 |
Solubility | Soluble in ethanol to 100 mM and in DMSO to 100 mM |
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Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H302:Harmful if swallowed |
Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
WGK Germany | 3 |
RIDADR | NONHforallmodesoftransport |