1.Gathercole LL, Lavery GG, Morgan SA, Cooper MS, Sinclair AJ, Tomlinson JW, Stewart PM. (2013) 11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects.. Endocr Rev, 34 (4):(525-55). [PMID:23612224]
2.Cheng Y, Wang L, Iacono L, Zhang D, Chen W, Gong J, Humphreys WG, Gan J. (2018) Clinical significance of CYP2C19 polymorphisms on the metabolism and pharmacokinetics of 11β-hydroxysteroid dehydrogenase type-1 inhibitor BMS-823778.. Br J Clin Pharmacol, 84 (1):(130-141). [PMID:28850715]
3.Gong J, Iacono L, Iyer RA, Humphreys WG, Zheng M. (2018) Physiologically-based pharmacokinetic modelling of a CYP2C19 substrate, BMS-823778, utilizing pharmacogenetic data.. Br J Clin Pharmacol, 84 (6):(1335-1345). [PMID:29469197]
4.Gong J, Hansen L, Iacono L. (2018) Clinical Pharmacokinetics and the Impact of Genetic Polymorphism on a CYP2C19 Substrate, BMS-823778, in Healthy Subjects.. Drug Metab Dispos, 46 (3):(316-325). [PMID:29311135]
5.Li J, Kennedy LJ, Walker SJ, Wang H, Li JJ, Hong Z, O'Connor SP, Ye XY, Chen S, Wu S et al.. (2018) Discovery of Clinical Candidate BMS-823778 as an Inhibitor of Human 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD-1).. ACS Med Chem Lett, 9 (12):(1170-1174). [PMID:30613321]
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