BMS 961 - ≥97%(HPLC), high purity , CAS No.185629-22-5

Item Number

B287305

Grouped product items
SKU	Size	Availability	Price	Qty
B287305-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$205.90
B287305-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$821.90

Selective RARγ agonist

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Basic Description

Synonyms	BMS961 \| BMS-961 \| US9963439, BMS961 \| SCHEMBL165751 \| AKOS024457614 \| 3-Fluoro-4-[[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8,-tetrahydro-2-naphthalenyl)acetyl]amino]-benzoic acid \| 3-fluoro-4-[[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphtha
Specifications & Purity	≥97%(HPLC)
Biochemical and Physiological Mechanisms	Selective RARγagonist (EC50values are 30 and 1000 nM at RARγand RARβrespectively). Displays no activity at RARαreceptors.
Storage Temp	Store at 2-8°C
Shipped In	Wet ice

Associated Targets(Human)

RARG Tclin Retinoic acid receptor gamma (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RARA Tclin Retinoic acid receptor alpha (1324 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RARG Tclin Retinoic acid receptor gamma (1154 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RARB Tclin Retinoic acid receptor beta (1232 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	3-fluoro-4-[[2-hydroxy-2-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)acetyl]amino]benzoic acid
INCHI	InChI=1S/C23H26FNO4/c1-22(2)9-10-23(3,4)16-11-13(5-7-15(16)22)19(26)20(27)25-18-8-6-14(21(28)29)12-17(18)24/h5-8,11-12,19,26H,9-10H2,1-4H3,(H,25,27)(H,28,29)
InChi Key	AANFHDFOMFRLLR-UHFFFAOYSA-N
Canonical SMILES	CC1(CCC(C2=C1C=CC(=C2)C(C(=O)NC3=C(C=C(C=C3)C(=O)O)F)O)(C)C)C
Isomeric SMILES	CC1(CCC(C2=C1C=CC(=C2)C(C(=O)NC3=C(C=C(C=C3)C(=O)O)F)O)(C)C)C
PubChem CID	2418
Molecular Weight	399.46

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Basic Description