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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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B646419-2mg | 2mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $194.90 | |
B646419-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $420.90 | |
B646419-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $600.90 | |
B646419-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,800.90 | |
B646419-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,520.90 |
Specifications & Purity | ≥99% |
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Biochemical and Physiological Mechanisms | BMS-983970 is an oral pan- Notch inhibitor for the treatment of multiplecancers. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | BMS-983970 is an oral pan- Notch inhibitor for the treatment of multiplecancers In Vivo BMS-983970 demonstrates anti-tumor activity in T-cell acute lymphoblastic leukemia (T-ALL) and solid tumor xenograft models . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Notch |
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IUPAC Name | (2S,3R)-2-(cyclopropylmethyl)-N'-[(3S)-9-fluoro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepin-3-yl]-3-(3,3,3-trifluoropropyl)butanediamide |
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INCHI | InChI=1S/C26H26F4N4O3/c27-19-8-4-7-17-20(15-5-2-1-3-6-15)32-23(25(37)33-21(17)19)34-24(36)16(11-12-26(28,29)30)18(22(31)35)13-14-9-10-14/h1-8,14,16,18,23H,9-13H2,(H2,31,35)(H,33,37)(H,34,36)/t16-,18+,23-/m1/s1 |
InChi Key | RANYIWAZSQWERN-WLENULPWSA-N |
Canonical SMILES | C1CC1CC(C(CCC(F)(F)F)C(=O)NC2C(=O)NC3=C(C=CC=C3F)C(=N2)C4=CC=CC=C4)C(=O)N |
Isomeric SMILES | C1CC1C[C@@H]([C@@H](CCC(F)(F)F)C(=O)N[C@@H]2C(=O)NC3=C(C=CC=C3F)C(=N2)C4=CC=CC=C4)C(=O)N |
PubChem CID | 73388374 |
Molecular Weight | 518.50 |
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Solubility | DMSO : ≥ 50 mg/mL (96.43 mM) |
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