BMS-983970 - 99%, high purity , CAS No.1584713-87-0

  • ≥99%
Item Number
B646419
Grouped product items
SKUSizeAvailabilityPrice Qty
B646419-2mg
2mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$194.90
B646419-5mg
5mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$420.90
B646419-10mg
10mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$600.90
B646419-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,800.90
B646419-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,520.90

Basic Description

Specifications & Purity≥99%
Biochemical and Physiological MechanismsBMS-983970 is an oral pan- Notch inhibitor for the treatment of multiplecancers.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

BMS-983970 is an oral pan- Notch inhibitor for the treatment of multiplecancers

In Vivo

BMS-983970 demonstrates anti-tumor activity in T-cell acute lymphoblastic leukemia (T-ALL) and solid tumor xenograft models . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:Notch

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (2S,3R)-2-(cyclopropylmethyl)-N'-[(3S)-9-fluoro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepin-3-yl]-3-(3,3,3-trifluoropropyl)butanediamide
INCHI InChI=1S/C26H26F4N4O3/c27-19-8-4-7-17-20(15-5-2-1-3-6-15)32-23(25(37)33-21(17)19)34-24(36)16(11-12-26(28,29)30)18(22(31)35)13-14-9-10-14/h1-8,14,16,18,23H,9-13H2,(H2,31,35)(H,33,37)(H,34,36)/t16-,18+,23-/m1/s1
InChi Key RANYIWAZSQWERN-WLENULPWSA-N
Canonical SMILES C1CC1CC(C(CCC(F)(F)F)C(=O)NC2C(=O)NC3=C(C=CC=C3F)C(=N2)C4=CC=CC=C4)C(=O)N
Isomeric SMILES C1CC1C[C@@H]([C@@H](CCC(F)(F)F)C(=O)N[C@@H]2C(=O)NC3=C(C=CC=C3F)C(=N2)C4=CC=CC=C4)C(=O)N
PubChem CID 73388374
Molecular Weight 518.50

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : ≥ 50 mg/mL (96.43 mM)

Related Documents

Solution Calculators