Bortezomib (PS-341) - ≥98%, high purity , 26S proteosome inhibitor, CAS No.179324-69-7, 26S proteosome inhibitor

Item Number

B125789

• Synonyms: CS-1039 | LDP 341 | BORTEZOMIB [MART.] | N-((1S)-1-benzyl-2-(((1R)-1-(dihydroxyboranyl)-3-methylbutyl)amino)2-oxoethylpyrazinecarboxamide | N-[(1R)-1-(dihydroxyboranyl)-3-methylbutyl]-N(alpha)-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide | N-[(1R)-1-(DIHYDR
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Bortezomib, a first-in-class proteasome inhibitor, induces apoptosis and growth arrest and reverses chemoresistance in myeloma cells and has demonstrated no irreversible adverse effect on haematopoietic stem cells. Bortezomib has shown in vitro and in viv
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: 26S proteosome inhibitor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Bortezomib (PS-341) is a potent 20S proteasome inhibitor with Ki of 0.6 nM in a cell-free assay.
A selective and robust 26S proteasome inhibitor