BRACO 19 trihydrochloride - ≥95%(HPLC), high purity , CAS No.1177798-88-7

  • ≥95%(HPLC)
Item Number
B287457
Grouped product items
SKUSizeAvailabilityPrice Qty
B287457-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
B287457-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,049.90

Telomerase inhibitor

Basic Description

SynonymsN,N'-[9[[4-(Dimethylamino)phenyl]amino]-3,6-acridinediyl]bis-1-pyrrolidinepropanamide trihydrochloride
Specifications & Purity≥95%(HPLC)
Biochemical and Physiological MechanismsTelomerase inhibitor (IC50= 115 nM). Inhibits expression of human telomerase reverse transcriptase (hTERT), induces cellular senescence and inhibits growth of uterine cancer cellsin vitro. Inhibits growth of uterine tumor xenografts in mice.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

TERT Tchem Telomerase reverse transcriptase (2428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name N-[9-[4-(dimethylamino)anilino]-6-(3-pyrrolidin-1-ylpropanoylamino)acridin-3-yl]-3-pyrrolidin-1-ylpropanamide;trihydrochloride
INCHI InChI=1S/C35H43N7O2.3ClH/c1-40(2)28-11-7-25(8-12-28)38-35-29-13-9-26(36-33(43)15-21-41-17-3-4-18-41)23-31(29)39-32-24-27(10-14-30(32)35)37-34(44)16-22-42-19-5-6-20-42;;;/h7-14,23-24H,3-6,15-22H2,1-2H3,(H,36,43)(H,37,44)(H,38,39);3*1H
InChi Key MJAPNWJRLLDPAB-UHFFFAOYSA-N
Canonical SMILES CN(C)C1=CC=C(C=C1)NC2=C3C=CC(=CC3=NC4=C2C=CC(=C4)NC(=O)CCN5CCCC5)NC(=O)CCN6CCCC6.Cl.Cl.Cl
Isomeric SMILES CN(C)C1=CC=C(C=C1)NC2=C3C=CC(=CC3=NC4=C2C=CC(=C4)NC(=O)CCN5CCCC5)NC(=O)CCN6CCCC6.Cl.Cl.Cl
PubChem CID 10349800
Molecular Weight 703.14

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySolvent:water, Max Conc. mg/mL: 35.16, Max Conc. mM: 50; Solvent:DMSO, Max Conc. mg/mL: 35.16, Max Conc. mM: 50

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Solution Calculators