BRD-7389 - 98%, high purity , CAS No.376382-11-5

  • ≥98%
Item Number
B276067
Grouped product items
SKUSizeAvailabilityPrice Qty
B276067-1mg
1mg
In stock
$30.90
B276067-5mg
5mg
In stock
$119.90
B276067-10mg
10mg
In stock
$183.90
B276067-25mg
25mg
In stock
$412.90
B276067-50mg
50mg
In stock
$741.90

p90 ribosomal S6 kinase RSK inhibitor

Basic Description

SynonymsOprea1_487649 | 1-Phenethylamino-3H-naphtho[1,2,3-de]quinoline-2,7-dione | AKOS000594176 | IDI1_025137 | CCG-120899 | 1-[(2-phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione | NCGC00177846-03 | Q27165722 | BAS 05532738 | SCHEMBL21461689 | HMS1493
Specifications & Purity≥98%
Biochemical and Physiological Mechanismsp90 ribosomal S6 kinase RSK inhibitor (IC 50 values are 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2 respectively). Upregulates insulin expression in pancreatic α-cells. Shows reprogramming effects in terminally differentiated cells.
Storage TempProtected from light,Store at -20°C,Desiccated
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 16-(2-phenylethylamino)-14-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(16),2,4,6,9(17),10,12-heptaene-8,15-dione
INCHI InChI=1S/C24H18N2O2/c27-23-17-10-5-4-9-16(17)21-20-18(23)11-6-12-19(20)26-24(28)22(21)25-14-13-15-7-2-1-3-8-15/h1-12,25H,13-14H2,(H,26,28)
InChi Key XASCINRGTHLHGM-UHFFFAOYSA-N
Canonical SMILES C1=CC=C(C=C1)CCNC2=C3C4=CC=CC=C4C(=O)C5=C3C(=CC=C5)NC2=O
Isomeric SMILES C1=CC=C(C=C1)CCNC2=C3C4=CC=CC=C4C(=O)C5=C3C(=CC=C5)NC2=O
PubChem CID 1080352
Molecular Weight 366.41

Certificates

Certificate of Analysis(COA)

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5 results found

Lot NumberCertificate TypeDateItem
K2215415Certificate of AnalysisAug 21, 2023 B276067
K2215416Certificate of AnalysisAug 21, 2023 B276067
K2215417Certificate of AnalysisAug 21, 2023 B276067
K2215418Certificate of AnalysisAug 21, 2023 B276067
K2215419Certificate of AnalysisAug 21, 2023 B276067

Chemical and Physical Properties

SolubilitySoluble in DMSO to 100 mM
SensitivityLight sensitive

Related Documents

Solution Calculators