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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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B276067-1mg | 1mg | In stock | $30.90 | |
B276067-5mg | 5mg | In stock | $119.90 | |
B276067-10mg | 10mg | In stock | $183.90 | |
B276067-25mg | 25mg | In stock | $412.90 | |
B276067-50mg | 50mg | In stock | $741.90 |
p90 ribosomal S6 kinase RSK inhibitor
Synonyms | Oprea1_487649 | 1-Phenethylamino-3H-naphtho[1,2,3-de]quinoline-2,7-dione | AKOS000594176 | IDI1_025137 | CCG-120899 | 1-[(2-phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione | NCGC00177846-03 | Q27165722 | BAS 05532738 | SCHEMBL21461689 | HMS1493 |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | p90 ribosomal S6 kinase RSK inhibitor (IC 50 values are 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2 respectively). Upregulates insulin expression in pancreatic α-cells. Shows reprogramming effects in terminally differentiated cells. |
Storage Temp | Protected from light,Store at -20°C,Desiccated |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 16-(2-phenylethylamino)-14-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(16),2,4,6,9(17),10,12-heptaene-8,15-dione |
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INCHI | InChI=1S/C24H18N2O2/c27-23-17-10-5-4-9-16(17)21-20-18(23)11-6-12-19(20)26-24(28)22(21)25-14-13-15-7-2-1-3-8-15/h1-12,25H,13-14H2,(H,26,28) |
InChi Key | XASCINRGTHLHGM-UHFFFAOYSA-N |
Canonical SMILES | C1=CC=C(C=C1)CCNC2=C3C4=CC=CC=C4C(=O)C5=C3C(=CC=C5)NC2=O |
Isomeric SMILES | C1=CC=C(C=C1)CCNC2=C3C4=CC=CC=C4C(=O)C5=C3C(=CC=C5)NC2=O |
PubChem CID | 1080352 |
Molecular Weight | 366.41 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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K2215415 | Certificate of Analysis | Aug 21, 2023 | B276067 |
K2215416 | Certificate of Analysis | Aug 21, 2023 | B276067 |
K2215417 | Certificate of Analysis | Aug 21, 2023 | B276067 |
K2215418 | Certificate of Analysis | Aug 21, 2023 | B276067 |
K2215419 | Certificate of Analysis | Aug 21, 2023 | B276067 |
Solubility | Soluble in DMSO to 100 mM |
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Sensitivity | Light sensitive |