BRL-15572 - 98%, high purity , CAS No.193611-72-2, Agonist of 5-HT 1A receptor;Agonist of 5-HT 1B receptor;Agonist of 5-HT 1D receptor;Agonist of 5-ht 1e receptor;Agonist of 5-HT 1F receptor;Agonist of 5-HT 2A receptor;Agonist of 5-HT 2B receptor;Agonist of 5-HT 2C receptor;Agonist of 5-HT 6 receptor

Item Number
B129690
Grouped product items
SKUSizeAvailabilityPrice Qty
B129690-1mg
1mg
In stock
$11.90
B129690-5mg
5mg
In stock
$48.90
B129690-10mg
10mg
In stock
$78.90
B129690-50mg
50mg
In stock
$197.90

Basic Description

SynonymsDTXSID70872473 | BRL-15572dihydrochloride | BRL 15573 dihydrochloride | s2677 | CS-0423 | HY-13200 | 3-(4-(3-chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride | CCG-269542 | AKOS027420454 | BRL-15572 2HCl | BRL-15572 (dihydrochloride) |
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological Mechanisms

BRL-15572 is a selective h5-HT1D antagonist, BRL-15572 displays 60-fold selectivity over h5-HT1B, and exhibits little or no affinity for a range of other receptor types.

Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of 5-HT 1A receptor;Agonist of 5-HT 1B receptor;Agonist of 5-HT 1D receptor;Agonist of 5-ht 1e receptor;Agonist of 5-HT 1F receptor;Agonist of 5-HT 2A receptor;Agonist of 5-HT 2B receptor;Agonist of 5-HT 2C receptor;Agonist of 5-HT 6 receptor

Associated Targets(Human)

HTR1B Tclin 5-hydroxytryptamine receptor 1B (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2A Tclin 5-hydroxytryptamine receptor 2A (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR1E Tchem 5-hydroxytryptamine receptor 1E (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR1D Tclin 5-hydroxytryptamine receptor 1D (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR1F Tclin 5-hydroxytryptamine receptor 1F (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2C Tclin 5-hydroxytryptamine receptor 2C (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR1A Tclin 5-hydroxytryptamine receptor 1A (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR6 Tchem 5-hydroxytryptamine receptor 6 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2B Tclin 5-hydroxytryptamine receptor 2B (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol;dihydrochloride
INCHI InChI=1S/C25H27ClN2O.2ClH/c26-22-12-7-13-23(18-22)28-16-14-27(15-17-28)19-24(29)25(20-8-3-1-4-9-20)21-10-5-2-6-11-21;;/h1-13,18,24-25,29H,14-17,19H2;2*1H
InChi Key WPEXRXMQMPOHIO-UHFFFAOYSA-N
Canonical SMILES C1CN(CCN1CC(C(C2=CC=CC=C2)C3=CC=CC=C3)O)C4=CC(=CC=C4)Cl.Cl.Cl
Isomeric SMILES C1CN(CCN1CC(C(C2=CC=CC=C2)C3=CC=CC=C3)O)C4=CC(=CC=C4)Cl.Cl.Cl
Alternate CAS 734517-40-9
PubChem CID 9891303
Molecular Weight 479.87

Certificates

Certificate of Analysis(COA)

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4 results found

Lot NumberCertificate TypeDateItem
K2112218Certificate of AnalysisAug 17, 2023 B129690
K2112241Certificate of AnalysisAug 17, 2023 B129690
K2112242Certificate of AnalysisAug 17, 2023 B129690
K2112265Certificate of AnalysisAug 17, 2023 B129690

Chemical and Physical Properties

SolubilityDMSO 96 mg/mL Water <1 mg/mL Ethanol 40 mg/mL

Related Documents

Solution Calculators