BRL 37344, sodium salt - ≥98%(HPLC), high purity , CAS No.127299-93-8

  • ≥98%(HPLC)
Item Number
B288470
Grouped product items
SKUSizeAvailabilityPrice Qty
B288470-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$113.90
B288470-10mg
10mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$174.90
B288470-25mg
25mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$393.90
B288470-50mg
50mg
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$735.90

β3agonist

Basic Description

SynonymsAODBGHUVYYWBRL-KNVOCYPGSA-N | (+/-)-(R*,R*)-[4-[2-[[2-(3-CHLOROPHENYL)-2-HYDROXYETHYL] AMINO]PROPYL]PHENOXY]-ACETIC ACID SODIUM | BRL 37344, SODIUM SALT | FT-0651577 | (R*,R*)-(+/-)-4-[2-[(2-(3-Chlorophenyl)-2-hydroxyethyl)amino]propyl]phenoxyacetic acid,
Specifications & Purity≥98%(HPLC)
Biochemical and Physiological MechanismsPotent and selectiveβ3adrenoceptor agonist (Kivalues are 287, 1750 and 1120 nM forβ3,β1andβ2receptors respectively).
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads

Associated Targets(Human)

ADRB2 Tclin Beta-2 adrenergic receptor (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRB3 Tclin Beta-3 adrenergic receptor (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB3 Tclin Beta-3 adrenergic receptor (5850 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB1 Tclin Adrenergic receptor beta; ADRB1 & ADRB3 (200 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name sodium;2-[4-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy]acetate
INCHI InChI=1S/C19H22ClNO4.Na/c1-13(21-11-18(22)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(23)24;/h2-8,10,13,18,21-22H,9,11-12H2,1H3,(H,23,24);/q;+1/p-1/t13-,18+;/m1./s1
InChi Key SNJIJYKMYQRHRC-WJKBNZMCSA-M
Canonical SMILES CC(CC1=CC=C(C=C1)OCC(=O)[O-])NCC(C2=CC(=CC=C2)Cl)O.[Na+]
Isomeric SMILES C[C@H](CC1=CC=C(C=C1)OCC(=O)[O-])NC[C@@H](C2=CC(=CC=C2)Cl)O.[Na+]
PubChem CID 16219010
Molecular Weight 385.82

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySolvent:water, Max Conc. mg/mL: 38.58, Max Conc. mM: 100
Sensitivitymoisture sensitive

Related Documents

Solution Calculators