Brompheniramine hydrogen maleate - ≥98%, high purity , Histamine H1 receptor antagonist, CAS No.980-71-2, Histamine H1 receptor antagonist

  • ≥98%
Item Number
B129275
Grouped product items
SKUSizeAvailabilityPrice Qty
B129275-50mg
50mg
In stock
$90.90
B129275-250mg
250mg
In stock
$409.90
B129275-1g
1g
In stock
$1,474.90
B129275-5g
5g
In stock
$6,633.90
B129275-25g
25g
In stock
$29,852.90
B129275-100g
100g
In stock
$107,469.90
View related series
Histamine receptor antagonists

Basic Description

SynonymsBrompheniramine Maleate (1:1) | Dimotane | 2-Pyridinepropanamine, gamma-(4-bromophenyl)-N,N-dimethyl-, (Z)-butenedioate (1:1) | BROMPHENIRAMINE MALEATE (MART.) | Gammistin | NCGC00093676-01 | NCGC00093676-02 | 2-Pyridinepropanamine, gamma-(4-bromophenyl)-
Specifications & Purity≥98%
Biochemical and Physiological MechanismsBrompheniramine Maleate is a histamine H1 receptors antagonist. Brompheniramine Maleate also functions as a moderately effective anticholinergic agent, and is likely an antimuscarinic agent similar to other common antihistamines such as diphenhydramine. B
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Action TypeANTAGONIST
Mechanism of actionHistamine H1 receptor antagonist
Product Description

Brompheniramine hydrogen maleate is a histamine H1 receptors antagonist.
A histamine H1 receptors antagonist

Associated Targets(Human)

KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCC2 Tchem Canalicular multispecific organic anion transporter 1 (1191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCB11 Tchem Bile salt export pump (2311 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCC3 Tbio Canalicular multispecific organic anion transporter 2 (718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCC4 Tchem Multidrug resistance-associated protein 4 (785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

ampC Beta-lactamase AmpC (62480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
pfk 6-phospho-1-fructokinase (7870 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488195225
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488195225
IUPAC Name 3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine;(Z)-but-2-enedioic acid
INCHI InChI=1S/C16H19BrN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChi Key SRGKFVAASLQVBO-BTJKTKAUSA-N
Canonical SMILES CN(C)CCC(C1=CC=C(C=C1)Br)C2=CC=CC=N2.C(=CC(=O)O)C(=O)O
Isomeric SMILES CN(C)CCC(C1=CC=C(C=C1)Br)C2=CC=CC=N2.C(=C\C(=O)O)\C(=O)O
WGK Germany 1
PubChem CID 5281067
Molecular Weight 435.31

Certificates

Certificate of Analysis(COA)

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13 results found

Lot NumberCertificate TypeDateItem
E23121062Certificate of AnalysisMar 03, 2023 B129275
E23121220Certificate of AnalysisMar 03, 2023 B129275
E23121221Certificate of AnalysisMar 03, 2023 B129275
E23121226Certificate of AnalysisMar 03, 2023 B129275
E23121227Certificate of AnalysisMar 03, 2023 B129275
E23121228Certificate of AnalysisMar 03, 2023 B129275
E23121231Certificate of AnalysisMar 03, 2023 B129275
E23121234Certificate of AnalysisMar 03, 2023 B129275
E2312735Certificate of AnalysisMar 03, 2023 B129275
E2312862Certificate of AnalysisMar 03, 2023 B129275
E1908013Certificate of AnalysisJan 19, 2023 B129275
E1520117Certificate of AnalysisDec 07, 2022 B129275
H2215258Certificate of AnalysisAug 17, 2022 B129275

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Chemical and Physical Properties

SolubilityDMSO mg/mL Water mg/mL Ethanol mg/mL
Melt Point(°C)136 °C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

Precautionary Statements

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P312+P330:IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. Rinse mouth.

WGK Germany 1
Merck Index 1443

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Solution Calculators