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Brr2 Inhibitor C9 - 98%, high purity , CAS No.2104030-82-0

  • ≥98%
Item Number
B412565
Grouped product items
SKUSizeAvailabilityPrice Qty
B412565-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$29.90
B412565-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$121.90
B412565-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
B412565-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$399.90
B412565-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$629.90
B412565-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$999.90

DNA/RNA Synthesis Inhibitors

View related series
DNA/RNA synthesis inhibitor

Basic Description

Specifications & Purity≥98%
Biochemical and Physiological MechanismsBrr2 inhibitor C9 (Brr2 Inhibitor 9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa a group of progressive retinal degenerative disorders.
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads

Associated Targets

DHX29 Tbio ATP-dependent RNA helicase DHX29 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SNRNP200 Tchem U5 small nuclear ribonucleoprotein 200 kDa helicase 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

EIF4A1 Tchem Eukaryotic initiation factor 4A-I 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

EIF4A3 Tchem Eukaryotic initiation factor 4A-III 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 6-benzyl-3-[3-(1,3-thiazol-5-ylmethoxy)phenyl]-1,4-dihydropyrido[4,3-d]pyrimidine-2,7-dione
INCHI InChI=1S/C24H20N4O3S/c29-23-10-22-18(13-27(23)12-17-5-2-1-3-6-17)14-28(24(30)26-22)19-7-4-8-20(9-19)31-15-21-11-25-16-32-21/h1-11,13,16H,12,14-15H2,(H,26,30)
InChi Key GAWVULNDIBAUHU-UHFFFAOYSA-N
Canonical SMILES C1C2=CN(C(=O)C=C2NC(=O)N1C3=CC(=CC=C3)OCC4=CN=CS4)CC5=CC=CC=C5
Isomeric SMILES C1C2=CN(C(=O)C=C2NC(=O)N1C3=CC(=CC=C3)OCC4=CN=CS4)CC5=CC=CC=C5
PubChem CID 132585219
Molecular Weight 444.51

Certificates

Certificate of Analysis(COA)

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12 results found

Lot NumberCertificate TypeDateItem
B2402101Certificate of AnalysisDec 29, 2023 B412565
B2402102Certificate of AnalysisDec 29, 2023 B412565
B2402103Certificate of AnalysisDec 29, 2023 B412565
B2402104Certificate of AnalysisDec 29, 2023 B412565
B2402105Certificate of AnalysisDec 29, 2023 B412565
B2402106Certificate of AnalysisDec 29, 2023 B412565
B2402107Certificate of AnalysisDec 29, 2023 B412565
B2402108Certificate of AnalysisDec 29, 2023 B412565
B2402109Certificate of AnalysisDec 29, 2023 B412565
B2402110Certificate of AnalysisDec 29, 2023 B412565
B2402111Certificate of AnalysisDec 29, 2023 B412565
B2402112Certificate of AnalysisDec 29, 2023 B412565

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Chemical and Physical Properties

SolubilitySolubility (25°C) In vitro DMSO: 89 mg/mL (200.22 mM); Ethanol: 2 mg/mL (4.49 mM); Water: Insoluble;
SensitivityLight sensitive

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