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Brr2 Inhibitor C9 - 98%, high purity , CAS No.2104030-82-0

≥98%

CAS#: 2104030-82-0
Formula: C₂₄H₂₀N₄O₃S
Molecular Weight: 444.51
PubChem CID: 132585219

Item Number

B412565

Grouped product items
SKU	Size	Availability	Price
B412565-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$29.90
B412565-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$121.90
B412565-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$199.90
B412565-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$399.90
B412565-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$629.90
B412565-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$999.90

DNA/RNA Synthesis Inhibitors

View related series

DNA/RNA synthesis inhibitor

Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Brr2 inhibitor C9 (Brr2 Inhibitor 9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa a group of progressive retinal degenerative disorders.
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads

Associated Targets(Human)

SNRNP200 Tchem U5 small nuclear ribonucleoprotein 200 kDa helicase (1 Activities)

Discover Target: SNRNP200

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

EIF4A1 Tchem Eukaryotic initiation factor 4A-I (286 Activities)

Discover Target: EIF4A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DHX29 Tbio ATP-dependent RNA helicase DHX29 (17 Activities)

Discover Target: DHX29

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	6-benzyl-3-[3-(1,3-thiazol-5-ylmethoxy)phenyl]-1,4-dihydropyrido[4,3-d]pyrimidine-2,7-dione
INCHI	InChI=1S/C24H20N4O3S/c29-23-10-22-18(13-27(23)12-17-5-2-1-3-6-17)14-28(24(30)26-22)19-7-4-8-20(9-19)31-15-21-11-25-16-32-21/h1-11,13,16H,12,14-15H2,(H,26,30)
InChi Key	GAWVULNDIBAUHU-UHFFFAOYSA-N
Canonical SMILES	C1C2=CN(C(=O)C=C2NC(=O)N1C3=CC(=CC=C3)OCC4=CN=CS4)CC5=CC=CC=C5
Isomeric SMILES	C1C2=CN(C(=O)C=C2NC(=O)N1C3=CC(=CC=C3)OCC4=CN=CS4)CC5=CC=CC=C5
PubChem CID	132585219
Molecular Weight	444.51

Certificates

Certificate of Analysis(COA)

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12 results found

Lot Number	Certificate Type	Date	Item
B2402101	Certificate of Analysis	Dec 29, 2023	B412565
B2402102	Certificate of Analysis	Dec 29, 2023	B412565
B2402103	Certificate of Analysis	Dec 29, 2023	B412565
B2402104	Certificate of Analysis	Dec 29, 2023	B412565
B2402105	Certificate of Analysis	Dec 29, 2023	B412565
B2402106	Certificate of Analysis	Dec 29, 2023	B412565
B2402107	Certificate of Analysis	Dec 29, 2023	B412565
B2402108	Certificate of Analysis	Dec 29, 2023	B412565
B2402109	Certificate of Analysis	Dec 29, 2023	B412565
B2402110	Certificate of Analysis	Dec 29, 2023	B412565
B2402111	Certificate of Analysis	Dec 29, 2023	B412565
B2402112	Certificate of Analysis	Dec 29, 2023	B412565

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Solubility

Solubility (25°C) In vitro DMSO: 89 mg/mL (200.22 mM); Ethanol: 2 mg/mL (4.49 mM); Water: Insoluble;

Sensitivity

Light sensitive

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Brr2 Inhibitor C9 - 98%, high purity , CAS No.2104030-82-0

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action