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Bruceine B - 99%, high purity , CAS No.25514-29-8
Ketones, Aldehydes, Acids
Basic Description Synonyms AKOS030573658 | Picras-3-en-21-oic acid, 15-(acetyloxy)-13,20-epoxy-3,11,12-trihydroxy-2,16-dioxo-, methyl ester, (11beta,12alpha,15beta)- | MS-28937 | Q27105981 | HY-N3013 | BRUCEIN B | methyl (1R,2S,3R,6R,8R,13S,14R,15R,16S,17S)-3-acetyloxy-10,15,16-tri Specifications & Purity ≥99% Biochemical and Physiological Mechanisms Bruceine B inhibits protein synthesis and nucleic acid synthesis. Storage Temp Protected from light,Store at -80°C Shipped In Ice chest + Ice pads Product Description Bruceine B inhibits protein synthesis and nucleic acid synthesis.
In Vitro
Bruceine B exhibits an IC 50 of 10 nM for antimalarial activity. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name methyl (1R,2S,3R,6R,8R,13S,14R,15R,16S,17S)-3-acetyloxy-10,15,16-trihydroxy-9,13-dimethyl-4,11-dioxo-5,18-dioxapentacyclo[12.5.0.01,6.02,17.08,13]nonadec-9-ene-17-carboxylate INCHI InChI=1S/C23H28O11/c1-8-10-5-12-22-7-32-23(20(30)31-4,17(22)15(19(29)34-12)33-9(2)24)18(28)14(27)16(22)21(10,3)6-11(25)13(8)26/h10,12,14-18,26-28H,5-7H2,1-4H3/t10-,12+,14+,15+,16+,17+,18-,21-,22+,23-/m0/s1 InChi Key YDWODLQEUPYKGJ-LZFWDZGBSA-N Canonical SMILES CC1=C(C(=O)CC2(C1CC3C45C2C(C(C(C4C(C(=O)O3)OC(=O)C)(OC5)C(=O)OC)O)O)C)O Isomeric SMILES CC1=C(C(=O)C[C@]2([C@H]1C[C@@H]3[C@]45[C@@H]2[C@H]([C@@H]([C@]([C@@H]4[C@H](C(=O)O3)OC(=O)C)(OC5)C(=O)OC)O)O)C)O Alternate CAS 25514-29-8 PubChem CID 161496 MeSH Entry Terms bruceine B Molecular Weight 480.46
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