Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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B129941-50mg | 50mg | In stock | $33.90 | |
B129941-100mg | 100mg | In stock | $46.90 | |
B129941-250mg | 250mg | In stock | $79.90 | |
B129941-1g | 1g | In stock | $259.90 | |
B129941-5g | 5g | In stock | $899.90 |
Synthetic glucocorticoid; anti-inflammatory and chemopreventive
Synonyms | BUDESONIDE COMPONENT OF SYMBICORT | Entocort EC | Pulmaxan turbohaler | Pulmicort Topinasal | Budesonide; 16?,17-[(1RS)-butylidenebis(oxy)]-11?,21-dihydroxypregna-1,4-diene-3,20-dione | 16-alpha,17-alpha-Butylidenedioxy-11-beta,21-dihydroxy-1,4-pregnadien |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Synthetic anti-inflammatory glucocorticoid that displays chemopreventive activity. Prevents formation of lung adenomas and adenocarcinomas in mice following inhalation or oral administration. Reverses DNA hypomethylation and modulates expression of cancer |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor;Agonist of Progesterone receptor |
Product Description |
Roquinimex is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF alpha.
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ALogP | 2.5 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 488195221 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488195221 |
IUPAC Name | (1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one |
INCHI | InChI=1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1 |
InChi Key | VOVIALXJUBGFJZ-KWVAZRHASA-N |
Canonical SMILES | CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C |
Isomeric SMILES | CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@@]5([C@H]4[C@H](C[C@@]3([C@@]2(O1)C(=O)CO)C)O)C |
WGK Germany | 3 |
RTECS | TU3723000 |
PubChem CID | 5281004 |
Molecular Weight | 430.53 |
PubChem CID | 5281004 |
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ChEMBL Ligand | CHEMBL1370 |
Wikipedia | Budesonide |
DrugBank Ligand | DB01222 |
CAS Registry No. | 51333-22-3 |
ChEBI | CHEBI:3207 |
PEP | budesonide |
Reactome Reaction | R-HSA-9678925 |
Reactome Drug | R-ALL-9660774 |
DrugCentral Ligand | 419 |
PubChem SID | 488195221 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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A2404040 | Certificate of Analysis | Dec 27, 2023 | B129941 |
F2427059 | Certificate of Analysis | Dec 27, 2023 | B129941 |
A2404465 | Certificate of Analysis | Dec 27, 2023 | B129941 |
A2404462 | Certificate of Analysis | Dec 27, 2023 | B129941 |
A2404461 | Certificate of Analysis | Dec 27, 2023 | B129941 |
A2404066 | Certificate of Analysis | Dec 27, 2023 | B129941 |
A2404058 | Certificate of Analysis | Dec 27, 2023 | B129941 |
A2404057 | Certificate of Analysis | Dec 27, 2023 | B129941 |
A2404056 | Certificate of Analysis | Dec 27, 2023 | B129941 |
A2404055 | Certificate of Analysis | Dec 27, 2023 | B129941 |
A2404039 | Certificate of Analysis | Dec 27, 2023 | B129941 |
C2321381 | Certificate of Analysis | Jan 11, 2023 | B129941 |
C2321406 | Certificate of Analysis | Jan 11, 2023 | B129941 |
C2321411 | Certificate of Analysis | Jan 11, 2023 | B129941 |
C2321415 | Certificate of Analysis | Jan 11, 2023 | B129941 |
C2321421 | Certificate of Analysis | Jan 11, 2023 | B129941 |
C2321450 | Certificate of Analysis | Jan 11, 2023 | B129941 |
C2321459 | Certificate of Analysis | Jan 11, 2023 | B129941 |
C2321472 | Certificate of Analysis | Jan 11, 2023 | B129941 |
C2321510 | Certificate of Analysis | Jan 11, 2023 | B129941 |
C2321566 | Certificate of Analysis | Jan 11, 2023 | B129941 |
Solubility | Solvent:DMSO, Max Conc. mg/mL: 43.05, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 21.52, Max Conc. mM: 50 |
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Pictogram(s) | GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H412:Harmful to aquatic life with long lasting effects H302:Harmful if swallowed H317:May cause an allergic skin reaction H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled H312:Harmful in contact with skin H332:Harmful if inhaled H372:Causes damage to organs through prolonged or repeated exposure H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P319:Get medical help if you feel unwell. P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately. |
WGK Germany | 3 |
RTECS | TU3723000 |
Starting at $640.90
1. Pengfei Li, Ruiming Yin, Yunfei Bai, Yanhong Ding, Xiaofeng Zeng, Yongquan Li. (2023) Enhanced thermal conductivity of Si3N4 ceramics through pyrolytic carbon prepared by gel casting using DMAA. Journal of Materials Research and Technology-JMR&T, 25 (1179). [PMID:] [10.1016/j.jmrt.2023.05.251] |
2. Shuang Yin, Dongliang Mao, Limei Pan, Xia Fang, Yang Wang, Tai Qiu, Jian Yang. (2021) Porous SiC–Si3N4 composite ceramics with excellent EMW absorption property prepared by gelcasting using DMAA. CERAMICS INTERNATIONAL, 47 (27058). [PMID:] [10.1016/j.ceramint.2021.06.119] |
3. An Kai, Guan Lianxiong, Kang Huiting, Tian Dating. (2021) Zipper-like thermosensitive molecularly imprinted polymers based on konjac glucomannan for metformin hydrochloride. IRANIAN POLYMER JOURNAL, 30 (4): (331-342). [PMID:] [10.1007/s13726-020-00892-8] |
4. Jing Li, Jindi Huang, Ruiming Yin. (2019) Multistage kinetic analysis of DMAA/MBAM polymer removal from gelcast ceramic parts using a multi-stage parallel reaction model and model-free method. RSC Advances, 9 (47): (27305-27317). [PMID:35529202] [10.1039/C9RA04489B] |
5. Jing Li, Chuanfu Zhang, Ruiming Yin, Wenhai Zhang. (2019) DAEM kinetics analysis and finite element simulation of thermal debinding process for a gelcast SiAlON green body. CERAMICS INTERNATIONAL, 45 (8166). [PMID:] [10.1016/j.ceramint.2019.01.118] |
1. Lichtenstein GR, Hanauer SB, Sandborn WJ, Practice Parameters Committee of American College of Gastroenterology. (2009) Management of Crohn's disease in adults.. Am J Gastroenterol, 104 (2): (465-83; quiz 464, 484). [PMID:19174807] [10.1021/op500134e] |
2. Habal FM, Huang VW. (2012) Review article: a decision-making algorithm for the management of pregnancy in the inflammatory bowel disease patient.. Aliment Pharmacol Ther, 35 (5): (501-15). [PMID:22221203] [10.1021/op500134e] |
3. Ramakrishnan S, Nicolau Jr DV, Langford B, Mahdi M, Jeffers H, Mwasuku C, Krassowska K, Fox R, Binnian I, Glover V et al.. (2021) Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial.. Lancet Respir Med, 71 (13): (1755-70). [PMID:33844996] [10.1016/S2213-2600(21)00160-0] |
4. Pengfei Li, Ruiming Yin, Yunfei Bai, Yanhong Ding, Xiaofeng Zeng, Yongquan Li. (2023) Enhanced thermal conductivity of Si3N4 ceramics through pyrolytic carbon prepared by gel casting using DMAA. Journal of Materials Research and Technology-JMR&T, 25 (1179). [PMID:] [10.1016/j.jmrt.2023.05.251] |
5. Shuang Yin, Dongliang Mao, Limei Pan, Xia Fang, Yang Wang, Tai Qiu, Jian Yang. (2021) Porous SiC–Si3N4 composite ceramics with excellent EMW absorption property prepared by gelcasting using DMAA. CERAMICS INTERNATIONAL, 47 (27058). [PMID:] [10.1016/j.ceramint.2021.06.119] |
6. An Kai, Guan Lianxiong, Kang Huiting, Tian Dating. (2021) Zipper-like thermosensitive molecularly imprinted polymers based on konjac glucomannan for metformin hydrochloride. IRANIAN POLYMER JOURNAL, 30 (4): (331-342). [PMID:] [10.1007/s13726-020-00892-8] |
7. Jing Li, Jindi Huang, Ruiming Yin. (2019) Multistage kinetic analysis of DMAA/MBAM polymer removal from gelcast ceramic parts using a multi-stage parallel reaction model and model-free method. RSC Advances, 9 (47): (27305-27317). [PMID:35529202] [10.1039/C9RA04489B] |
8. Jing Li, Chuanfu Zhang, Ruiming Yin, Wenhai Zhang. (2019) DAEM kinetics analysis and finite element simulation of thermal debinding process for a gelcast SiAlON green body. CERAMICS INTERNATIONAL, 45 (8166). [PMID:] [10.1016/j.ceramint.2019.01.118] |