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Budesonide - 98%, high purity , CAS No.51333-22-3, Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor;Agonist of Progesterone receptor

  • Moligand™
  • ≥98%
Item Number
B129941
Grouped product items
SKUSizeAvailabilityPrice Qty
B129941-50mg
50mg
In stock
$33.90
B129941-100mg
100mg
In stock
$46.90
B129941-250mg
250mg
In stock
$79.90
B129941-1g
1g
In stock
$259.90
B129941-5g
5g
In stock
$899.90
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Bulk Order  SDS  DATASHEET

Synthetic glucocorticoid; anti-inflammatory and chemopreventive

View related series
Glucocorticoid receptor Agonist Mineralocorticoid receptor Agonist Progesterone receptor Agonist

Basic Description

Synonymsbudesonide|Pulmicort|Entocort|51333-22-3|Rhinocort|Preferid|Budeson|Rhinocort Aqua|Entocort EC|Cortivent|Micronyl|Respules|Spirocort|Bidien|Uceris|Pulmicort Respules|Budesonidum|Rhinocort alpha|Pulmicort Flexhaler|Budesonido|Budecort Inhaler|Fvolir|Rhinoc
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsSynthetic anti-inflammatory glucocorticoid that displays chemopreventive activity. Prevents formation of lung adenomas and adenocarcinomas in mice following inhalation or oral administration. Reverses DNA hypomethylation and modulates expression of cancer
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor;Agonist of Progesterone receptor
Product Description

Roquinimex is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF alpha.

Product Properties

ALogP2.5

Names and Identifiers

Pubchem Sid488195221
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488195221
IUPAC Name (1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
INCHI InChI=1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1
InChi Key VOVIALXJUBGFJZ-KWVAZRHASA-N
Canonical SMILES CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C
Isomeric SMILES CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@@]5([C@H]4[C@H](C[C@@]3([C@@]2(O1)C(=O)CO)C)O)C
WGK Germany 3
RTECS TU3723000
PubChem CID 5281004
Molecular Weight 430.53

Certificates

Certificate of Analysis(COA)

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21 results found

Lot NumberCertificate TypeDateItem
A2404040Certificate of AnalysisDec 27, 2023 B129941
F2427059Certificate of AnalysisDec 27, 2023 B129941
A2404465Certificate of AnalysisDec 27, 2023 B129941
A2404462Certificate of AnalysisDec 27, 2023 B129941
A2404461Certificate of AnalysisDec 27, 2023 B129941
A2404066Certificate of AnalysisDec 27, 2023 B129941
A2404058Certificate of AnalysisDec 27, 2023 B129941
A2404057Certificate of AnalysisDec 27, 2023 B129941
A2404056Certificate of AnalysisDec 27, 2023 B129941
A2404055Certificate of AnalysisDec 27, 2023 B129941
A2404039Certificate of AnalysisDec 27, 2023 B129941
C2321381Certificate of AnalysisJan 11, 2023 B129941
C2321406Certificate of AnalysisJan 11, 2023 B129941
C2321411Certificate of AnalysisJan 11, 2023 B129941
C2321415Certificate of AnalysisJan 11, 2023 B129941
C2321421Certificate of AnalysisJan 11, 2023 B129941
C2321450Certificate of AnalysisJan 11, 2023 B129941
C2321459Certificate of AnalysisJan 11, 2023 B129941
C2321472Certificate of AnalysisJan 11, 2023 B129941
C2321510Certificate of AnalysisJan 11, 2023 B129941
C2321566Certificate of AnalysisJan 11, 2023 B129941

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Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 43.05, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 21.52, Max Conc. mM: 50

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Danger
Hazard Statements

H412:Harmful to aquatic life with long lasting effects

H302:Harmful if swallowed

H317:May cause an allergic skin reaction

H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled

H312:Harmful in contact with skin

H332:Harmful if inhaled

H372:Causes damage to organs through prolonged or repeated exposure

H361:Suspected of damaging fertility or the unborn child

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P284:[In case of inadequate ventilation] Wear respiratory protection.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P301+P317:IF SWALLOWED: Get medical help.

P318:if exposed or concerned, get medical advice.

P317:Get emergency medical help.

P319:Get medical help if you feel unwell.

P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately.

WGK Germany 3
RTECS TU3723000

Related Documents

 SDS

 Specification Sheet

Alternative Products

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    Budesonide-d8

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  2. Necrox-5 methanesulfonate
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    Starting at $49.90

  3. 6β-Hydroxy 21-Acetyloxy Budesonide
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    Starting at $285.90

  4. Budesonide-d6
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    Starting at $697.90

  5. 23-Hydroxybudesonide
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  6. 6β-Hydroxy Budesonide - , used for , CAS No. 88411-77-2, by Aladdin Scientific
    6β-Hydroxy Budesonide

    Starting at $712.90

  7. 9,11-Anhydrobudesonide
    9,11-Anhydrobudesonide

    Starting at $285.90

  8. 9α-Bromobudesonide
    9α-Bromobudesonide

    Starting at $285.90

  9. 21-Acetyloxy Budesonide-d8
    21-Acetyloxy Budesonide-d8

    Starting at $285.90

  10. (22R)-Budesonide - 98% (R, S mixture), used for , CAS No. 51372-29-3, by Aladdin Scientific
    (22R)-Budesonide

    Starting at $640.90

  11. 14,15-Dehydro Budesonide
    14,15-Dehydro Budesonide

    Starting at $697.90

  12. 6β-Hydroxy budesonide-d8
    6β-Hydroxy budesonide-d8

    Starting at $570.90

  13. Budesonide - 10mM in DMSO, used for , CAS No. 51333-22-3(DMSO), by Aladdin Scientific
    Budesonide, Glucocorticoid receptor agonist

    Starting at $47.90

References

1. Lichtenstein GR, Hanauer SB, Sandborn WJ, Practice Parameters Committee of American College of Gastroenterology.  (2009)  Management of Crohn's disease in adults..  Am J Gastroenterol,  104  (2): (465-83; quiz 464, 484).  [PMID:19174807]
2. Habal FM, Huang VW.  (2012)  Review article: a decision-making algorithm for the management of pregnancy in the inflammatory bowel disease patient..  Aliment Pharmacol Ther,  35  (5): (501-15).  [PMID:22221203]
3. Ramakrishnan S, Nicolau Jr DV, Langford B, Mahdi M, Jeffers H, Mwasuku C, Krassowska K, Fox R, Binnian I, Glover V et al..  (2021)  Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial..  Lancet Respir Med,  129  (3): (589-97).  [PMID:33844996]

Solution Calculators

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