Budesonide - 10mM in DMSO, high purity , Glucocorticoid receptor agonist, CAS No.51333-22-3(DMSO), Glucocorticoid receptor agonist

Item Number

B580318

Grouped product items
SKU	Size	Availability	Price	Qty
B580318-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$47.90

Synthetic glucocorticoid; anti-inflammatory and chemopreventive

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Basic Description

Synonyms	budesonide\|Pulmicort\|Entocort\|51333-22-3\|Rhinocort\|Preferid\|Budeson\|Rhinocort Aqua\|Entocort EC\|Cortivent\|Micronyl\|Respules\|Spirocort\|Bidien\|Uceris\|Pulmicort Respules\|Budesonidum\|Rhinocort alpha\|Pulmicort Flexhaler\|Budesonido\|Budecort Inhaler\|Fvolir\|Rhinoc
Specifications & Purity	Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms	Synthetic anti-inflammatory glucocorticoid that displays chemopreventive activity. Prevents formation of lung adenomas and adenocarcinomas in mice following inhalation or oral administration. Reverses DNA hypomethylation and modulates expression of cancer
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Glucocorticoid receptor agonist
Product Description	Budesonide, an inhaled glucocortical steroid, is a glucocorticoid receptor agonist. Budesonide decreases the size of lung tumors, reverses DNA hypomethylation and modulates mRNA expression of genes. Budesonide is an anti-inflammatory agent used for asthma。

Names and Identifiers

IUPAC Name	(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
INCHI	InChI=1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1
InChi Key	VOVIALXJUBGFJZ-KWVAZRHASA-N
Canonical SMILES	CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C
Isomeric SMILES	CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@@]5([C@H]4[C@H](C[C@@]3([C@@]2(O1)C(=O)CO)C)O)C
WGK Germany	3
RTECS	TU3723000
PubChem CID	5281004
Molecular Weight	430.53

WGK Germany

RTECS

TU3723000

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Basic Description