Bufexamac - ≥98.0%(HPLC), high purity , CAS No.2438-72-4, Inhibitor of histone deacetylase 10;Inhibitor of histone deacetylase 6

Item Number

B129286

• Synonyms: Spectrum_001754 | BDBM50015144 | BRN 2646848 | Bufexamac,(S) | HMS2095B08 | p-Butoxyphenylacetohydroxamic acid | BUFEXAMAC [JAN] | KBioGR_001593 | Prestwick1_000243 | EINECS 219-451-1 | KBioSS_002234 | Spectrum2_001457 | Flogocid N plastigel | Prestwick3_
• Specifications & Purity: Moligand™, ≥98%(HPLC)
• Biochemical and Physiological Mechanisms: Bufexamac is a specific inhibitor of HDAC6 and HDAC10. Treatment of peripheral blood mononuclear cells with bufexamac inhibits the secretion of IFN-α. Bufexamac is a frequent and relevant contact sensitizer.HDAC6 and HDAC10 inhibitor. NSAID. COX inhibitor
• Shipped In: Normal
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Inhibitor of histone deacetylase 10;Inhibitor of histone deacetylase 6
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Bufexamac is a COX inhibitor for IFN-α release with EC50 of 8.9 μM.
A HDAC6 and HDAC10 inhibitor.