Butein - ≥98.0%(HPLC), high purity , CAS No.487-52-5

Item Number

B135922

• Synonyms: butein | 487-52-5 | 2',3,4,4'-Tetrahydroxychalcone | 2',4',3,4-Tetrahydroxychalcone | 3,4,2',4'-Tetrahydroxychalcone | (E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one | AC1NQY7L | UNII-4WVS5M0LGF | 4WVS5M0LGF | EINECS 207-659-5 | CHEBI:3237 | NSC-652892 | (2E)
• Specifications & Purity: ≥98%(HPLC)
• Biochemical and Physiological Mechanisms: Dual c-Met and EGFR tyrosine kinase inhibitor. Inhibits MMP-9 expression and activity. Suppresses tumor cell invasion. Induces apoptosis. Shows anti-adipogenic effects. Shows antimetastatic and antitumor effects in vivo.
• Storage Temp: Store at -20°C,Argon charged
• Shipped In: Ice chest + Ice pads
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Butein, a plant polyphenol isolated from Rhus verniciflua, is able to inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, also inhibits EGFR.